815 Robotic Soliprep • automated, reproducible sample preparation at the highest level • saves space and is easy to operate • filtrates and homogenizes a large variety of samples Robotic Soliprep – your reliable partner in sample preparation 02 The Metrohm solution for your sample preparation For a long time now, Metrohm’s automation program The 815 Robotic Soliprep can be controlled by the proven has enabled the transfer of your titrimetric applications tiamo TM titration and control software or MagIC Net to a fully automatic system. The 815 Robotic Soliprep is software. Both permit the flexible programming of your a new version of the proven 815 Robotic USB Sample sample changer, include a powerful database and comply Processor that will enhance your daily routine work. The with all the relevant regulations such as 21 CFR Part 11. main application area of the Robotic Soliprep systems is professional sample preparation. The Robotic Soliprep family comprises four packages that cover different standard sample preparation steps. The core of the system is the 815 Robotic USB Sample Processor, which has established itself due to its flexibility and robustness. Depending on the sample preparation task it is equipped with the accessories needed to meet your requirements. You get exactly what you need – a com-pact, economical automation system for the preparation of your samples. The advantages of the Robotic Soliprep • Proven technology based on the Robotic USB Sample Processor 03 • Versatile, fully automatic sample preparation – kept simple • Saves time by automating routine tasks • Intelligent liquid handling – pipetting, dilution and more • Homogenization with one of the leading instruments on the market • Improved results thanks to the standardization of the sample preparation procedure • Reliable, robust and safe • Efficient sample preparation in a minimum of space • Attractive price • The control software leaves no wish unfulfilled Typical manual sample preparation steps Homogenizing 04 Homogenizing is a very important step in the preparation of samples that cannot be dissolved. Crushing with mor-tar and pistil is not only arduous and time-consuming but also produces inconsistent results. Filtering To avoid problems in the subsequent analysis due to particles that remain after the homogenization procedure, these particles must be filtered off, a step that is manda-tory before any chromatographic or photometric sample analysis. Liquid Handling Once the clear sample solution is obtained, it is metered with a glass pipette and, if necessary, mixed with reagents in preparation for the analysis. Analysis Depending on the substance to be determined, the analysis can be carried out directly in the homogenized sample or in the clear, exactly metered filtrate. Your sample preparation with the Robotic Soliprep – each step fully automatic Homogenizing 05 The Polytron® 1300D made by Kinematica ensures that each sample is treated in exactly the same way. Different dispersing aggregates are available and enable optimal matching of the homogenization procedure to your application. The duration of the homogenization procedure and the homogenizer speed are controlled by the software. Filtering With filtration using a syringe and disposable filters, the greatest challenge is to keep the pressure constant during sample introduction. The connected Dosino guarantees a steady addition of the sample solution. Commercially available syringe filters with standard Luer connector can be used directly with the Robotic Soliprep. Liquid handling The term liquid handling includes a lot more than just pipetting an exactly defined amount of sample. From dilution series to sample transfer into a sealed vessel, liquid handling nowadays knows almost no limits. Analysis Depending on the version, the system can be used ex clu sively for sample preparation or can be combined with a titrator or an ion chromatograph. This provides for complete documentation and traceability of the analysis and sample preparation. «Robotic Titration Soliprep» 06 «Robotic Titration Soliprep» is the complete package for tion. Because the sample frequently contains insoluble the titrimetric determination of samples that first have to auxiliary components, the dispersing aggregate of the be homogenized. It contains all the components for the homogenizer must be thoroughly cleaned after each use. fully automatic sample preparation and determination. This thorough cleaning of the aggregate is carried out fully automatically in the external rinsing station while the Cleanliness is all-important sample on the rack is being titrated. If required a further The Polytron® 1300D minimizes sample loss and saves cleaning agent can be added to the solution in the rins-time as it homogenizes the sample directly in the solu-ing station. The height-adjustable pivoting arm allows optimal position-ing of the Polytron. It also allows the exact addition of solvent immediately before the start of the homogenization Pivoting arm for Polytron. Together with the rinsing station, the tried-and-tested 772 07 Pump Unit constitutes the optimal cleaning unit. It’s up to you to decide whether the dispersing aggregate is to be cleaned by immersion in a cleaning solution or by spray nozzles. The powerful peristaltic pump leaves nothing to be desired. 772 Pump Unit. Robotic Titration Soliprep – homogenization and titration in one run. «Robotic Filtration Soliprep» 08 Analysis This fully automatic sample preparation system enables Everything clear? fast and efficient homogenization and filtration of your Fillers contained in the sample, to mention just one ex-samples. ample, interfere with the subsequent chromatographic or photometric determination. When manual filtration Solidly based on sample preparation with syringe and disposable filters is used for separation, It is widely known that meaningful and exact analyti-the required uniform filtration speed is difficult to achieve cal results are only possible with a sample preparation and the filtration requires lots of time and patience if re-that meets the highest demands. Thanks to the proven producible results are to be obtained. combination of Dosino and Polytron, the Robotic Soliprep performs this task reproducibly also at high sample throughputs. Right on target! The sophisticated mechanism for grabbing and dropping of tools such as one­way filters and syringes works without any user intervention. The used tools are collected in a bin that can be sealed and disposed of simply and safely. Collection bin for used tools. Forget bulky dosing devices that clutter your lab bench 09 – the Dosino is integrated in your Robotic Soliprep and mounted on the reagent bottle, which makes it an unri-valed space saver. Thanks to the proven Dosino technology it is possible to introduce sample solutions through the syringe filter under strictly uniform conditions. Analysis 800 Dosino with different Dosing Units. Robotic Filtration Soliprep – homogenization and filtration in one run. «Robotic Flexible Soliprep» 10 Analysis Make the Robotic Flexible Soliprep your sample prepa-with one push of a button while taking care of other ration station and experience the following advantages: work at the same time? The Robotic Flexible Soliprep makes this possible. Enjoy the freedom Work in today’s quality assurance laboratories is highly More than just homogenizing and filtering varied as each product requires specific preparation Thanks to its high flexibility this instrument can be adapt-procedures. The samples have to be homogenized, fil-ed to your wishes and requirements. It can, for example, tered, diluted and, possibly, dispensed into sealed vials fill the same sample into different vessels for additional using procedures that are tailor-made for each product. analyses and add auxiliary or stabilizing reagents com-Wouldn’t it be nice to carry out all these different steps pletely automatically. Flexible and still very safe Encoding enables each insert to be taken out for filling and reinserted correctly so that mix­ups are ruled out. Sample rack with code. The Metrohm Robotic Sample Processors excel by their 11 accuracy and robustness. The specially designed rein-forced pivoting arm handles any mechanical challenge with ease. Your Metrohm Robotic Soliprep works very precisely. Robotic Flexible Soliprep – your sample preparation station. 815 Robotic Soliprep for LC – automation for solid samples The old cliché, according to which ion chromatography The 815 Robotic Soliprep for LC is a version of the 815 12 is only suitable for analyzing liquid samples, is no longer Robotic USB Sample Processor XL. With this system all valid. Modern sample preparation and automation tech-manual steps can be automated in full. niques also allow gases and solids to be analyzed. With the 815 Robotic Soliprep for LC, Metrohm offers a modern automation solution for solid samples. Automatic sample preparation of various steps. In the first step, solvent is added, the sample comminuted and then homogenized. After that, sample is as-pirated with a metal­free needle, filtered and finally transferred directly to an LC system by way of a connection port. 13 In the Soliprep system the sample rack can be adapted individually to the particular application. Different inserts provide the highest degree of flexibility. 14 The 815 Robotic Soliprep for LC – more than a sample changer The 815 Robotic Soliprep for LC enables users to homog-the «Polytron»), for Liquid Handling (800 Dosinos and enize, extract, dilute and filter solid or liquid samples. 772 Pump Unit) and for transferring the prepared sample Sub se quently, the sample is transferred directly to an IC to an LC system (connector with capillary). 24 solid or HPLC system by way of a connector. Depending on samples in 120 mL vessels can be placed on the standard the requirements of the application, the 815 Robotic sample rack of the 815 Robotic Soliprep for LC. In addi-Soliprep offers enormous flexibility in the configuration tion, 30 sample vials (11 mL), 24 metal­free sample of the system and integrates all sample preparation steps needles and 24 syringe filters are available there. into a single, continuous and fully automated analytical se quence. To this end there is a selection of sample racks Applications from a variety of industrial sectors available, which can be equipped with various inserts. With the 815 Robotic Soliprep for LC the scope of use of ion chromatography can also be extended to solid The equipment of the 815 Robotic Soliprep for LC samples. Typical samples come from the pharmaceutical The 815 Robotic Soliprep for LC comprises not only an in dustry. However, this system is also ideally suited to the 815 Robotic USB Sample Processor XL with two work analysis of foods, feedstuffs and environmentally relevant stations, but also the equipment for homogenizing the samples such as sediments. sample («Polytron» homogenizer and washing station for The 815 Robotic Soliprep for LC for Inline Sample Preparation of solid samples. The worked-up sample is transferred directly to an IC or HPLC system. This fully automatic analytical system minimizes manual steps and guarantees complete traceability. 15 Ordering information 815 Robotic Soliprep 2.815.1110 815 Robotic Soliprep «Robotic Titration Soliprep»* 2.815.2110 815 Robotic Soliprep «Robotic Flexible Soliprep» 2.815.3110 815 Robotic Soliprep «Robotic Filtration Soliprep» 2.815.4110 815 Robotic Soliprep for LC Aggregates and electrodes have to be ordered separately Accessories Aggregates 6.9012.000 Dispersing aggregate for Polytron 115 mm 6.9012.010 Dispersing aggregate for Polytron 157 mm Sample beakers 6.1432.320 Sample beaker 250 mL made of glass 6.1453.250 Sample beaker 250 mL made of PP 6.1459.300 One­way sample beaker 120 mL made of PP (100 pieces) 6.2743.050 One­way sample beaker 11 mL made of PP (2000 pieces) * The titrator has to be ordered separately. www.metrohm.com ­9100 Herisau G, CH ohm A witzerland by Metr , printed in S SW ­08 Subject to change without notice Layout by Ecknauer+Schoch A 8.815.5002EN – 2015