General Catalog www.metrohm.com Herisau CH-9101 G, A ohm Metr by atalog 2014 witzerland S al C in Subject to modifications Printed 8.000.5112EN Gener Metrohm – precision measurement systems for chemical analysis made in Switzerland Metrohm AG, founded in 1943, is a worldwide leading manufacturer of precision instruments for chemical analysis. Our measurement instruments are found not only in the laboratories of practically every industry, but also in research institutes and government agencies. At our headquarters in Herisau in eastern Switzerland, we develop and produce measurement instruments for titration, ion chromatography, pH and conductivity measurement, voltammetry and stability measurement. Our product program is supplemented with dosing and Liquid Handling systems, solutions for the automation of sample preparation and analysis and sensors, columns and extensive accessories. In addition, we have been distributing a newly introduced program of systems for near-infrared analyses in the laboratory and process under the brand name Metrohm NIRSystems since 2013. Metrohm instruments are sold worldwide through a network of around 40 company-owned subsidiaries and through around 40 additional exclusive representatives. These also provide exclusive worldwide service and support under the name Metrohm. We see ourselves as problem solvers – both in the laboratory and in the industrial process. It is for that reason that we offer our customers tailored overall solutions that, in addition to the respective analysis instruments, also comprise the necessary application expertise. At our applications laboratories, our chemists are continuously developing new applications and methods, publishing them in specialist journals and thereby opening up new fields of application for our customers. Not at least, we distinguish ourselves from most of our – to some extent considerably larger – competitors by the fact that Metrohm AG has been wholly owned by the non-profit Metrohm Foundation since 1982. Table of contents pH/Conductivity measurement 1 Potentiometric and thermometric titration 11 Karl Fischer titration 33 Dosing devices 51 Automation in titration 59 Polarography, voltammetry and CVS 87 Stability measuring instruments 105 Near-infrared spectroscopy 113 Ion chromatography 129 Metrohm Quality Service 221 2 Kapiteltitel Kategorie pH/Conductivity measurement pH/Conductivity measurement 1 2 pH/conductivity measurement pH/Conductivity measurement pH and Ion meters 4 pH meter overview 4 826 pH mobile 5 827 pH lab 6 780 pH Meter 7 781 pH/Ion Meter 8 867 pH Module 9 Conductometer 10 856 Conductivity Module 10 pH/Conductivity measurement 3 pH and Ion meters pH meter overview 826 827 780 781 867 Measuring range pH 0 ...14 (-13 ... +20) 0 ...14 (±20) 0 ...14 (-13 ... +20) mV ±1200 ±2200 ±1200 Temperature Pt 1000 [°C] -150 ... +250 -150 ... +250 -150 ... +250 Temperature NTC [°C] -5 ... +250 -20 ... +250 -5 ... +250 Concentration − − 10-38... 10+38 10-21... 10+20 Resolution: pH 0.001 0.001 0.001 Resolution: U [mV] 0.1 0.1 0.1 Resolution: T [°C] 0.1 0.1 0.1 pH-calibration (number of buffers) 3 9 5 (Touch Control) / 9 ( tiamoTM) Stability control (drift display) x x x Plot function pH/mV/T versus time − x x Automatic buffer recognition x x x Saving of calibration data incl. graph only data graph and data graph and data Automatic temperature compensation x x x Automatic electrode test − x with Touch Control / tiamoTM Remote stirrer control − x x Handling of intelligent dosing elements − − x Automatic standard addition − − Dosimat Dosino/Dosimat Touch Control with color display or tiamo TM − − x Method memory − x x Result memory x x x Print out according to GLP/ISO x x x GLP/GMP and FDA compliance (21 CFR Part11) − − Touch Control / tiamo TM full Additional input for intelligent electrodes − − x Ipol or Upol integrated polarizer − − x Printer connection IrDA RS232 USB 2 USB connections for sample processor, printer, ... − − x MSB connection − 1 (stirrer) 4 (stirrer, Dosino) Sample processor (optional) − remote USB Line operation with 100 ... 240 V, 50/60 Hz Battery only x x x Lablink − − x Language English German, English, Spanish, German, English, French Spanish, French, Chinese, Portuguese, Russian, Polish, Italian, Japanese; Touch Control additionally in Korean; tiamo TM additionally in Slovak and Traditional Chinese 4 pH/Conductivity measurement 826 pH mobile The 826 pH mobile is a handy and very easy-to-operate pH meter with wireless Infrared interface for data trans- fer to a printer or PC. Numerous functions, e.g., input options for user and/or sample identification, three-point calibration with automatic buffer recognition and various monitoring functions make it possible to work in confor- mance with GLP anywhere. The measured value memory contains up to 200 measured values, including date, time and sample identification, and can be called up and/or sent to a printer or PC at any time. When the 6.0228.020 Primatrode is used, the 826 pH mobile fulfills protection class IP 67, i.e. even a brief immersion in water will not harm the instrument. Power supply is provided by means of four LR6, UM3 or AA batteries; approx. 750 hours operating time is possible in normal operations. Ordering Information 2.826.0010 826 pH mobile 2.826.0020 826 pH mobile with Primatrode 826 pH mobile 2.826.0110 826 pH mobile with carrying case pH/Conductivity measurement 5 827 pH lab The 827 pH lab is a handy and very easy to operate pH meter with wireless Infrared interface for daily routine work in the laboratory. Numerous functions, e.g., input options for user and/or sample identification, three-point calibration with automatic buffer recognition, automatic measured value acceptance and various monitoring func- tions make working in conformance with GLP child‘s play. The measured value memory contains up to 200 measured values, including date, time and sample identi- fication, and can be called up and/or sent to a printer or PC at any time. Ordering Information 2.827.0114 827 pH lab; 230 V, EU with Primatrode 2.827.0115 827 pH lab; 120 V, US with Primatrode 2.827.0117 827 pH lab; 240 V, AUS with Primatrode 2.827.0119 827 pH lab; 230 V, UK with Primatrode 2.827.0214 827 pH lab; 230 V, EU with Unitrode 2.827.0215 827 pH lab; 120 V, US with Unitrode 2.827.0217 827 pH lab; 240 V, AUS with Unitrode 827 pH lab 2.827.0219 827 pH lab; 230 V, UK with Unitrode 6 pH/Conductivity measurement 780 pH Meter Precision pH meter The 780 pH Meter offers a multitude of opportunities for pH measurements that meet the highest standards. In addition to the general functions of pH, voltage and temperature measurement, the 780 pH Meter is equipped with an automatic stirrer control, a multi-point calibration with up to nine buffers, a method memory and various monitoring functions for calibration and servicing. The automatic electrode test in conformance with GLP permits objective assessment of the electrode and leaves nothing more to chance. Reliable and reproducible results are thus guaranteed. The large backlit multi-line display provides an overview and makes the individual settings easy. The bidirectional RS-232 interface enables data transfer to a printer or PC. A sample changer can be connected through the optional 6.2148.010 Remote Box. Ordering Information 780 pH Meter 2.780.0010 780 pH Meter pH/Conductivity measurement 7 781 pH/Ion Meter Combined pH/ion meter Three different modes are available for ion measurement: direct measurement, standard or sample addition. In the The 781 pH/Ion Meter offers a multitude of possibilities case of fully automated standard addition with an op-for pH and ion measurements that meet the highest tional Dosimat, only the concentration of the standard standards. In addition to the general functions of pH, and the desired quantity of addition steps need to be ion, voltage and temperature measurement, the 781 pH entered, the pH/ion meter takes care of the rest. Up to Meter is equipped with an automatic stirrer control, a 19 standards can be used for the calibration for direct multi-point calibration with up to 9 buffers (pH mode), a measurement. methods memory and various monitoring functions for calibration and servicing. The automatic electrode test for pH glass electrodes in conformance with GLP permits objective assessment of the electrode and leaves nothing more to chance. Reliable and reproducible results are thus guaranteed. The large backlit multi-line display provides an overview and makes the individual settings easy. The bidirectional RS-232 interface enables data transfer to a printer or PC. A sample changer can be connected through the optional 6.2148.010 Remote Box. Ordering Information 781 pH/Ion Meter 2.781.0010 781 pH/Ion Meter 8 pH/Conductivity measurement 867 pH Module pH and ion measurement at the highest level is possible The instrument is equipped with 2 USB interfaces for with the 867 pH Module. It can be used as stand-alone connecting USB printers, Autosamplers or barcode read-instrument in conjunction with a 900 Touch Control or as ers and 4 MSB interfaces for connecting stirrers or dosing a supplement to a Titrando system. devices of the 800 Dosino type (for the controlled adding of auxiliary solutions or for the automated feed-through In addition to measurements of pH, temperature, mV, I , of the standard addition). pol U and concentration, standard additions (manual, dos, pol autodos) can also be carried out. In addition to conven- Both in combination with the Touch Control as stand-tional sensors, intelligent electrodes – „iTrodes“ – can alone pH meter and also integrated in tiamo TM full sys-also be used for measurement with the 867 pH Module. tems (from Version 2.0), it is in compliance with GLP and A polarized measuring input is available in addition. FDA requirements. The 867 pH Module is a modern pH/ion meter with auto- matic stirrer control and the option of operating intelli- gent dosing elements. Ordering Information 2.867.0010 867 pH Module 2.867.0110 867 pH Module with Touch Control 2.867.0210 867 pH Module with tiamo™ light Options 2.800.0010 800 Dosino 2.801.0010 801 Stirrer 2.802.0040 802 Stirrer (propeller stirrer) for 804 Ti Stand 2.804.0010 804 Ti Stand without stand rod 867 pH Module with 840 Touch Control 6.2151.000 Cable USB A – mini-DIN 8-pin pH/Conductivity measurement 9 Conductometer 856 Conductivity Module The 856 Conductivity Module can be used as stand-alone Thanks to the galvanically separated measuring input, pH instrument in combination with a 900 Touch Control or value and conductivity can be determined in the same as a supplement to a Titrando system. beaker without interference in conjunction with the 867 pH Module. The 856 Conductivity Module can perform measure- ments with the latest in conductivity measuring technol- The instrument is equipped with 2 USB interfaces for ogy, the 5-ring conductivity measuring cells. They reach connecting USB printers, Autosamplers or barcode read-a very high linearity without platinization of the cells. This ers and 4 MSB interfaces for connecting stirrers or dosing guarantees highest accuracy, and the cell constant, once devices of the 800 Dosino type (e.g., for adding auxiliary determined, remains constant over a wide measuring solutions). range. In contrast to the 4-ring cells, the electrode can be immersed completely into the beaker. This means not Both in conjunction with the 900 Touch Control as stand-only that beakers with different fill levels are no problem, alone conductivity measurement instrument and as an but also that rapid mixing within the measuring cell can integrated component in tiamo TM full (from Version 2.0), take place, even in stirred measuring solutions. Last but the 856 Conductivity Module is in compliance with GLP not least, the 5-ring conductivity measuring cell is very and FDA requirements. easy to clean, thanks to the removable cap. With the help of the optional 6.2103.160 Adapter box, the classical Metrohm conductivity measuring cells can also continue to be used with the instrument. Ordering Information 2.856.0010 856 Conductivity Module 2.856.0110 856 Conductivity Module with Touch Control, including 5-ring conductivity measuring cell 2.856.0120 856 Conductivity Module with Touch Control, including conductivity measuring cell (stainless steel) 2.856.0210 856 Conductivity Module with tiamo™ light, including 5-ring conductivity measuring cell 2.856.0220 856 Conductivity Module with tiamo™ light, including conductivity measuring cell (stainless steel) Options 2.801.0010 801 Stirrer 6.0915.100 5-ring conductivity measuring cell c = 0.7 cm-1 with Pt1000 6.0915.130 5-ring conductivity measuring cell c = 1.0 cm-1 with Pt1000 6.0916.040 Conductivity measuring cell made of stainless steel, c = 0.1 cm-1, with Pt1000 (St.N) 6.2103.160 Adapter 4 x socket B – plug N 856 Conductivity Module with tiamo™ 6.2151.000 Cable USB A – mini-DIN 8-pin 10 pH/Conductivity measurement Potentiometric and thermometric titration Potentiometric and thermometric titration 11 12 Potentiometric and thermometric titration Potentiometric and thermometric titration Potentiometric titrators – Overview 14 Potentiometric titrators – Titrino plus 26 Titrino plus – Introduction 26 Potentiometric titrators – Titrando 15 Titrino plus 27 Titrando family 15 848 Titrino plus 27 Titrando 16 877 Titrino plus 27 888 Titrando with Touch Control 16 Titrino plus packages 28 888 Titrando with tiamo TM light 16 Food/Beverage Titrino plus 28 902 Titrando 16 Food/Beverage Titrino plus with printer 28 904 Titrando 16 Salt Titrino plus 28 904 Titrando 17 Salt Titrino plus with printer 28 905 Titrando 17 Oil Titrino plus 29 905 Titrando 17 Oil Titrino plus with printer 29 906 Titrando 17 Optional accessories 30 906 Titrando 18 USB Thermal printer Neo‘s 30 907 Titrando 18 801 Stirrer with stand 30 907 Titrando 18 802 Stirrer (propeller stirrer) for 804 Ti Stand 30 Titrando packages 19 804 Ti Stand without stand rod 30 Surf Titrando Ionic 19 804 Ti Stand with stand 31 Surf Titrando Two Phase 19 869 Compact Sample Changer 31 Surf Titrando NIO 19 Plate Titrando 19 Thermometric titration 32 Oil Titrando 20 859 Titrotherm complete with tiamo™ 32 Food Titrando 20 Pharm Titrando 20 Input instruments and software 21 900 Touch Control 21 tiamo™ 2.4 Light CD: 1 license 21 tiamo™ 2.4 Full CD: 1 license 21 tiamo™ 2.4 Multi CD: 3 licenses 21 Optional accessories 22 800 Dosino 22 800 Dosino 22 801 Stirrer with stand 22 802 Stirrer (propeller stirrer) for 804 Ti Stand 22 804 Ti Stand without stand rod 23 804 Ti Stand with stand 23 805 Dosimat 23 846 Dosing Interface 23 856 Conductivity Module 24 867 pH Module 24 Potentiometric titrators – Ti-Touch 25 916 Salt Ti-Touch 25 916 Oil Ti-Touch 25 916 Food Ti-Touch 25 Potentiometric and thermometric titration 13 Potentiometric titrators – Overview Potentiometric Titrators Titrino plus Ti-Touch Titrando 870 877 848 915 916 888 890 901 902 904 905 906 907 Optional 2nd measuring interface − − − − − − − yes yes yes yes yes yes Intelligent Sensor «iTrodes» − − − − yes yes − yes yes yes yes yes yes Volumetric Karl Fischer Titration yes − − yes − − yes yes − − − yes yes Ion Measurement / Standardaddition − − − − − − − − − yes yes yes yes pH Measurement − yes yes − yes yes − yes yes yes yes yes yes Endpoint Titration − yes yes − yes yes − yes yes yes yes yes yes Dynamic Equivalence Point Titration − − yes − yes yes − − − yes yes yes yes Monotonic Equivalence Point Titration − yes yes − yes yes − − − yes yes yes yes Liquid Handling − − − yes − − − yes yes yes yes yes yes STAT Titration − − − − − − − − yes − − yes yes Dosino Technology − − − yes yes − − yes yes − yes − yes Software Control − − − − − yes yes yes yes yes yes yes yes Touch Control − − − yes yes yes yes yes yes yes yes yes yes Live Display yes yes yes yes yes yes yes yes yes yes yes yes yes Report Printing / LIMS yes yes yes yes yes yes yes yes yes yes yes yes yes PDF report without PC − − − yes yes yes yes yes yes yes yes yes yes Balance Connection via RS232 yes yes yes yes yes yes yes yes yes yes yes yes yes 14 Potentiometric and thermometric titration Potentiometric titrators – Titrando Titrando family Depending on the model, the Titrando supports the titra- The Dosino – space-saving modernity tion modes DET (dynamic equivalence point titration), With the Titrando, dosing is accomplished with Dosino MET (monotonic equivalence point titration) and SET and intelligent dosing unit, which are screwed directly (titration to one or two specified endpoints), KFT (volu-onto the reagent bottle. All of the data about the metric Karl Fischer titration) and pH-STAT. reagent and the dosing unit required for the titration is stored in the integrated data chip. Each dosing unit is Ion meter marked with a serial number and a cylinder number and Not only pH, voltage and temperature can be measured is shipped with an individual certificate. with the MEAS pH and MEAS CONC measuring modes. Direct concentration determination and standard addi- Intelligent electrodes „iTrodes“ tion with ion-selective electrodes are also possible. The integrated memory chip enables the saving of impor- tant sensor data such as article and serial numbers, cali- Comprehensive Liquid Handling bration data, calibration history, duration of use and Basic operations of everyday laboratory work such as calibration validity. All of the sensor data is uploaded pipetting, transferring, dosing, dispensing and diluting automatically when a connection is made with the become child‘s play, thanks to the Liquid Handling func-Titrando. This means that the possibility of mix-ups or tionality of the Titrando. Maximum accuracy and preci-editing errors is eliminated. The user is informed if the sion are guaranteed in the range of 10 µL to 100 mL. electrode type does not match the one defined in the method. Monitoring functions allow the exclusion of Measuring input electrodes whose calibration data lies outside the limit The measuring interface of the Titrando is comprised of values or whose calibration period has already expired. a connector for the intelligent „iTrodes“ electrodes, a high-ohm measuring input and a measuring input for Operation – The choice is up to you polarizable electrodes, in addition to one separate refer-The Touch Control is an ergonomic and up-to-date oper- ence input and one temperature input for Pt1000 or NTC ating element with direct network connection. Thanks to temperature sensors. The resolution of the inputs is at the new „Favorites“, you now have direct access to the 0.1 mV or 0.001 pH. Up to two galvanically isolated methods you use most frequently. measuring interfaces can be installed. The titration software tiamo™ offers, in addition to the MSB connector standard functions for controlling a Titrando via PC, Up to 4 Dosinos or Dosimats, 4 magnetic stirrers or rod numerous additional functionalities, e.g., a client/server stirrers and 4 Remote Boxes can be connected for auto-database or true parallel titration. mation with its four installed Metrohm Serial Buses (MSB connectors). This makes the modular Titrando system the Unlimited automation most flexible titration system on the market. The „Plug-Increasing numbers of samples, complicated sample pre- and-play“ functionality makes the manual configuration paration steps and unattended overnight operation soon of peripheral devices superfluous; the Titrando recog-justify the use of a sample changer. The Titrando is nizes the connected instrument automatically. equipped with the necessary intelligence for controlling sample changers. Whether it be large or small sample USB connector capacity, one or two workstations, sample measuring, Two USB ports are available for communication with sample preparation, Liquid Handling, or rinsing and cali-balances, printers or other USB-capable instruments. brating the electrodes – the USB Sample Processors offer Laboratory balances can be connected with the aid of an a high degree of automation with low investment costs. RS-232 converter. Potentiometric and thermometric titration 15 Titrando 888 Titrando with Touch Control (2.888.0110) High-end titrator with built-in buret drive • including 900 Touch Control, 801 Stirrer magnetic stirrer, exchange unit (20 mL) and combined „Ecotrode 888 plus“ Titr pH ando glass electrode • dynamic (DET), monotonic with (MET) and Touch endpoint titration Contr (SET) ol • four MSB connectors • one galvanically isolated measuring interface (also for intelligent „iTrodes“ electrodes) • USB connector 888 Titrando with tiamoTM light (2.888.0210) High-end titrator with built-in buret drive • including titration software tiamo TM light, 801 Stirrer magnetic stirrer, exchange unit (20 mL) and combined 888 „Ecotr Titr ode ando plus“ pH glass with electrode • dynamic (DET), monotonic (MET) and endpoint titration tiamo (SET) TM light • four MSB connectors • one galvanically isolated measuring interface (also for intelligent „iTrodes“ electrodes) • USB connector 902 Titrando (2.902.0010) High-end titrator for use with intelligent electrodes – iTrodes – with • up to four dosing systems of the 800 Dosino type 902 • Titr Endpoint titr ando ation (SET) • enzymatic and pH-STAT titrations (STAT) • Dosing functions with monitoring (DOS), Liquid Handling • four MSB connectors • one galvanically isolated measuring interface • USB connector 904 Titrando (2.904.0010) High-end titrator for use with intelligent electrodes – iTrodes – with • built-in buret drive 904 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET) • Measurement with ion-selective electrodes (MEAS CONC) • Dosing functions with monitoring, Liquid Handling • four MSB connectors • one galvanically isolated measuring interface • USB connector 16 Potentiometric and thermometric titration 904 Titrando (2.904.0020) High-end titrator for use with intelligent electrodes – iTrodes – with • built-in buret drive 904 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET) • Measurement with ion-selective electrodes • Dosing functions with monitoring, Liquid Handling • four MSB connectors • two galvanically isolated measuring interfaces • USB connector 905 Titrando (2.905.0010) High-end titrator for use with intelligent electrodes – iTrodes – with • up to four dosing systems of the 800 Dosino type 905 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET) • Measurement with ion-selective electrodes • Dosing functions (DOS), Liquid Handling • four MSB connectors • one galvanically isolated measuring interface • USB connector 905 Titrando (2.905.0020) High-end titrator for use with intelligent electrodes – iTrodes – with • up to four dosing systems of the 800 Dosino type 905 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET) • Measurement with ion-selective electrodes • Dosing functions (DOS), Liquid Handling • four MSB connectors • two galvanically isolated measuring interfaces • USB connector 906 Titrando (2.906.0010) High-end titrator for use with intelligent electrodes – iTrodes – with • built-in buret drive 906 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT) • Measurement with ion-selective electrodes • Dosing functions with monitoring, Liquid Handling • four MSB connectors and USB connector • one galvanically isolated measuring interface Potentiometric and thermometric titration 17 906 Titrando (2.906.0020) High-end titrator for use with intelligent electrodes – iTrodes – with • built-in buret drive 906 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT) • Measurement with ion-selective electrodes • Dosing functions with monitoring, Liquid Handling • four MSB connectors and USB connector • two galvanically isolated measuring interfaces 907 Titrando (2.907.0010) High-end titrator for use with intelligent electrodes – iTrodes – with • up to four dosing systems of the 800 Dosino type 907 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT) • Measurement with ion-selective electrodes • Dosing functions with monitoring, Liquid Handling • four MSB connectors and USB connector • one galvanically isolated measuring interface 907 Titrando (2.907.0020) High-end titrator for use with intelligent electrodes – iTrodes – with • up to four dosing systems of the 800 Dosino type 907 • Titr dynamic ando (DET), monotonic (MET) and endpoint titration (SET), enzymatic and pH-STAT titrations (STAT), Karl Fischer titration (KFT) • Measurement with ion-selective electrodes • Dosing functions with monitoring, Liquid Handling • four MSB connectors and USB connector • two galvanically isolated measuring interfaces 18 Potentiometric and thermometric titration Titrando packages Surf Titrando Ionic (2.905.1010) The Surf Titrando Ionic is based on the 905 Titrando and offers a complete package for the most common analyses of ionic surfactants. Apart from the titration Surf software Titr tiamo TM ando light an Ionic d determination methods described in detail, you will also receive comprehensive accessories for your titrations. Surf Titrando Two Phase (2.905.1020) The Surf Titrando Two Phase is based on the 905 Titrando and offers a complete package for the most common analyses of ionic surfactants. Apart from the titration Surf software Titr tiamo TM ando light an Td wo determi Phase nation methods described in detail, you will also receive comprehensive accessories for your titrations. Surf Titrando NIO (2.905.2010) The Surf Titrando NIO is based on the 905 Titrando and offers a complete package for the most common analyses of non-ionic surfactants. Apart from the Surf titration Titr softwa ando re tiamo TM NIO light and determination methods described in detail, you wil also receive comprehensive accessories for your titrations. Plate Titrando (2.905.2020) The Plate Titrando is based on the 905 Titrando and offers a complete package for the most common analyses of plating baths. Apart from the titration Plate software ti Titr amo TM ando light and determination methods described in detail, you will also receive comprehensive accessories for your titrations. Potentiometric and thermometric titration 19 Oil Titrando (2.905.3010) The Oil Titrando is based on the 905 Titrando and offers a complete package for the most common analyses of petrochemical products. Apart from the titration soft-Oil ware Titr tiamo TM ando light and determination methods described in detail, you will also receive comprehensive accessories for your titrations. Food Titrando (2.905.4010) The Food Titrando is based on the 905 Titrando and offers a complete package for the most common analyses of foodstuffs. Apart from the titration soft-Food ware tiamo TM Titr light ando and determination methods described in detail, you will also receive comprehensive accessories for your titrations. Pharm Titrando (2.907.1020) The Pharm Titrando is based on the 907 Titrando and offers a complete package for the most common analyses of pharmaceutical products. Apart from Pharm the titration Titr software ando tiamo TM full and determination methods described in detail, you will also receive comprehensive accessories for your titrations. 20 Potentiometric and thermometric titration Input instruments and software 900 Touch Control (2.900.0010) Operating unit for the Titrandos, USB Sample Processors, 856 Conductivity Module, 867 pH Module and 846 Dosing Interface. Touch-sensitive, high-resolution color 900 display, Touch simple and Contr intuitive oper ol ation, thanks to favorites for direct method access. With integrated Ethernet inter- face for direct connection to the Internet and USB inter- face for connecting USB printers or a USB memory stick. tiamo™ 2.4 Light CD: 1 license (6.6056.241) Computer program for controlling a titration system. • Up to two Metrohm instruments can be connected • Graphical method editor with numerous templates tiamo • Layout ™ manager 2.4 for Light individual CD: monitor 1 interface • Database with reevaluation and report generator license • No parallel titration, no data export • Languages: German, English, French, Italian, Spanish, Portuguese, Polish, Russian, Slovak, Japanese, Chinese, Traditional Chinese tiamo™ 2.4 Full CD: 1 license (6.6056.242) Computer program for controlling titration systems. • Graphical method editor with numerous templates • Layout manager for individual monitor interface tiamo • Database ™ with r 2.4 F eevaluation ull and r CD: eport 1 generator • Export to LIMS, NuGenesis, Cyberlab, etc. license • In compliance with the directives according to FDA 21 CFR Part 11 • Parallel titration • Languages: German, English, French, Italian, Spanish, Portuguese, Polish, Russian, Slovak, Japanese, Chinese, Traditional Chinese tiamo™ 2.4 Multi CD: 3 licenses (6.6056.243) Computer program for controlling titration systems. • Client/server version for network operation • Graphical method editor with numerous templates tiamo • Layout ™ manager 2.4 for Multi individual CD: monitor 3 interface • Database with reevaluation and report generator licenses • Export to LIMS, NuGenesis, Cyberlab, etc. • In compliance with the directives according to FDA 21 CFR Part 11 • Parallel titration • Languages: German, English, French, Italian, Spanish, Portuguese, Polish, Russian, Slovak, Japanese, Chinese, Traditional Chinese Potentiometric and thermometric titration 21 Optional accessories 800 Dosino (2.800.0010) Drive with write/read hardware for intelligent Dosing Units. With fixed cable (length 150 cm). 800 Dosino 800 Dosino (2.800.0020) Drive with write/read hardware for intelligent dosing units. With permanently attached cable (length 65 cm). 800 Dosino 801 Stirrer with stand (2.801.0040) Magnetic stirrer including base plate, support rod and electrode holder for supplementing the Titrino plus, Dosimat plus, Titrandos, Sample Processors, 805 Dosimat 801 and Stirr 780/781 pH er with meters as well stand as the 856 and 867 measuring modules. With permanently attached cable for MSB (Metrohm Serial Bus). 802 Stirrer (propeller stirrer) for 804 Ti Stand (2.802.0040) Rod stirrer with 6.1909.010 Propeller stirrer. 802 Stirrer (propeller stir- rer) for 804 Ti Stand 22 Potentiometric and thermometric titration 804 Ti Stand without stand rod (2.804.0010) Titration stand and controller for 802 Stirrer. The 804 Ti Stand together with the optional 802 Stirrer provides an alternative to the magnetic stirrer. Without stand. 804 Ti Stand without stand rod 804 Ti Stand with stand (2.804.0040) Titration stand and controller for 802 Rod Stirrer. The 804 Ti Stand together with the optional 802 Rod Stirrer pro- vides an alternative to the magnetic stirrer. Ti Stand with 804 base Ti plate, Stand support rod and with electrode stand holder. 805 Dosimat (2.805.0010) Dosing device for the Titrando and Sample Processors with read/write hardware for intelligent Exchange Units. With permanently attached cable. Without Exchange 805 Unit. Dosimat 846 Dosing Interface (2.846.0010) USB-capable control unit for connecting a maximum of four 800 Dosinos or 805 Dosimats for dosing and Liquid Handling tasks. A Touch Control or the connection to a 846 PC with Dosing tiamo™, MagIC Interface Net, viva or 797 VA Computrace is required for operation. Potentiometric and thermometric titration 23 856 Conductivity Module (2.856.0010) Conductivity measurement module as supplement to a Titrando or „stand-alone“ in combination with a 900 Touch Control. 856 Conductivity Module 867 pH Module (2.867.0010) Module for pH/ion measurement as supplement to a Titrando or „stand-alone“ in combination with a 900 Touch Control. 867 pH Module 24 Potentiometric and thermometric titration Potentiometric titrators – Ti-Touch 916 Salt Ti-Touch (2.916.2010) „Reduce to the max“ – this is the 916 Ti-Touch‘s concept. The new compact Titrator from Metrohm offers the maximum in the class of stand-alone systems for routine 916 analysis. The „916 Salt Salt Ti-T Ti- ouch“ Touch contains the complete accessories for chloride titration. 916 Oil Ti-Touch (2.916.3010) „Reduce to the max“ – this is the 916 Ti-Touch‘s concept. The new compact Titrator from Metrohm offers the maximum in the class of stand-alone systems for routine 916 analysis. The Oil „916 Oil Ti-T Ti-T ouch“ ouch contains the complete accessories for non-aqueous titration (acid number / base number). 916 Food Ti-Touch (2.916.4010) „Reduce to the max“ – this is the 916 Ti-Touch‘s concept. The new compact Titrator from Metrohm offers the maximum in the class of stand-alone systems for routine 916 analysis. The „91 F 6 ood Food Ti Ti- -Touc T h“ouch contains the complete accessories for the most important aqueous acid/base titrations – not only in the area of food analysis. Potentiometric and thermometric titration 25 Potentiometric titrators – Titrino plus Titrino plus – Introduction The Titrino plus, Metrohm‘s entry class in the area of measuring input that guarantees results with the greatest potentiometric titration, is particularly attractive due to of precision. its practically unbelievable price-performance ratio. A large live display with titration curve, „Plug & Play“ func-Maximum ease of installation tionality of exchange unit, stirrer and USB printer, a high-The installation of a Titrino plus is designed to be ex-precision measuring input, operation with keyboard – ceptionally simple. Exchange unit, stirrer and USB com-the Titrino plus offers considerably more than you would pact printer are detected and configured automatically as ever expect in this price segment. Their robustness also soon as they are connected. makes them the ideal titrators for routine determinations in everyday laboratory operations. Mouse or keys – select your favorite! The Titrino plus can be controlled either per mouseclick Potentiometric titration or keyboard. A USB port is available for communication The 877 Titrino plus supports the titration modes MET with balances or printers. The optional 6.2148.030 USB/ (monotonic equivalence point titration) and SET (titration RS-232 adapter box enables the connection of laboratory to one or two specified endpoints). The 848 Titrino plus balances and operation with a computer. supports in addition the titration mode DET (dynamic equivalence point titration). Intelligent exchange unit for more convenience The chip for the intelligent Metrohm exchange unit auto- The live curve brings it to light matically provides the titrator with the data (cylinder Every Titrino plus is equipped with a live curve display. volume, type of reagent, date of expiration for the titer, This means that you are always informed of the progress etc.) that it requires to accomplish the titrations error-of the titration. free. This means that you will always titer under optimum conditions and that you will not need, for example, to Maximum precision thanks to the new measuring repeat any measurements because of an expired titer. input The Titrino plus is equipped with a high-resolution 26 Potentiometric and thermometric titration Titrino plus 848 Titrino plus (2.848.0010) Compact titrator for • dynamic (DET) titrations with automatic equivalence point finding 848 • Titrino monotonic (MET) titr plus ations with automatic equiva- lence point finding • endpoint titrations (SET) 877 Titrino plus (2.877.0010) Compact titrator for • potentiometric endpoint titrations (SET) • monotonic titrations with automatic equivalence point 877 Titrino finding (MET) plus Potentiometric and thermometric titration 27 Titrino plus packages Food/Beverage Titrino plus (2.848.1010) The Food/Beverage Titrino plus offers you the complete package for all conventional analyses in food analysis. In addition to the more than 100 determination methods Food/Bever described in detail, age you also r Titrino eceive the accessories for your titrations. plus Food/Beverage Titrino plus with printer (2.848.1020) The Food/Beverage Titrino plus offers you the complete package for all conventional analyses in food analysis. In addition to the more than 100 determination methods Food/Bever described in detail, age you also r Titrino eceive the accessories for your titrations. Including USB thermal printer Neo‘s. plus with printer Salt Titrino plus (2.848.2010) The Salt Titrino plus offers you the complete package for the analysis of chloride in a wide variety of samples. In addition to the determination methods described in Salt detail, Titrino you also receive plus the complete accessories for your titrations. Salt Titrino plus with printer (2.848.2020) The Salt Titrino plus offers you the complete package for the analysis of chloride in a wide variety of samples. In addition to the determination methods described in Salt detail, Titrino you also receive plus the with complete prin accessories for - your titrations. Including USB thermal printer Neo‘s. ter 28 Potentiometric and thermometric titration Oil Titrino plus (2.848.3010) The Oil Titrino plus offers you the complete package for the determination of the acid and base numbers of oil products. In addition to the determination methods Oil describTitrino ed in detail, plus you also receive the complete accessories for your titrations. Oil Titrino plus with printer (2.848.3020) The Oil Titrino plus offers you the complete package for the determination of the acid and base numbers of oil products. In addition to the determination methods Oil describTitrino ed in detail, plus you also with receive t prin he com -plete accessories for your titrations. Including USB thermal ter printer Neo‘s. Potentiometric and thermometric titration 29 Optional accessories USB Thermal printer Neo‘s (2.141.0100) Compact printer with USB interface for the Titrino plus and Dosimat plus. Paper width 60 mm (40 characters). Including 6.2151.120 USB USB Thermal cable. printer Neo‘s 801 Stirrer with stand (2.801.0040) Magnetic stirrer including base plate, support rod and electrode holder for supplementing the Titrino plus, Dosimat plus, Titrandos, Sample Processors, 805 Dosimat 801 and Stirr 780/781 pH er with meters as well stand as the 856 and 867 measuring modules. With permanently attached cable for MSB (Metrohm Serial Bus). 802 Stirrer (propeller stirrer) for 804 Ti Stand (2.802.0040) Rod stirrer with 6.1909.010 Propeller stirrer. 802 Stirrer (propeller stir- rer) for 804 Ti Stand 804 Ti Stand without stand rod (2.804.0010) Titration stand and controller for 802 Stirrer. The 804 Ti Stand together with the optional 802 Stirrer provides an alternative to the magnetic stirrer. Without stand. 804 Ti Stand without stand rod 30 Potentiometric and thermometric titration 804 Ti Stand with stand (2.804.0040) Titration stand and controller for 802 Rod Stirrer. The 804 Ti Stand together with the optional 802 Rod Stirrer provides an alternative to the magnetic stirrer. Ti Stand 804 with Ti base S plate, tand support r with od and electr stand ode holder. 869 Compact Sample Changer (2.869.0010) The 869 Compact Sample Changer offers automation in a minimum amount of space. 869 Compact Sample Changer Potentiometric and thermometric titration 31 Thermometric titration 859 Titrotherm complete with tiamo™ Computer-controlled titrator for thermometric titration. The Titrotherm 859 – state-of-the-art USB tech-Including complete accessories for the titration (10 mL nology buret, titration stand with rod stirrer, Thermoprobe, titra-Thanks to state-of-the-art USB technology, the instrument tion vessel and tiamo™ light). is detected and configured automatically by the tiamo™ titration software at the time of connection to the com- Benefits of thermometric titration puter. The same applies to all the dosing units, stirrers • Rapid and robust method for routine operation and sensors connected to the Titrotherm. • One sensor for all applications – no interacting with the sample or the solvent The proven tiamo™ software enables a rapid, goal- • Maintenance-free sensor – no calibration necessary oriented method development, in addition to a simple • Suitable for aggressive media generation of results. The endpoints are determined • No membrane or diaphragm problems automatically; reproducibility can be enhanced even more when additional optimization parameters are used. Thermometric titration is a highly versatile determination The generation of reports is accomplished using method-method. In principle, it is suitable for every reaction that specific form sheets that can be designed to suit. causes a sufficiently large temperature change in the sample solution. It is therefore particularly suitable for Thermoprobe – rapid, precise and robust applications The temperature sensor (thermistor) based on semicon- • for which no suitable potentiometric sensor or refer-ductor technology has impressive properties: Its response ence electrolyte is available time is only 0.3 s and its resolution is 10-5 K, thus ena- • for which the sample disrupts the electrode bling it to follow every temperature change both rapidly • for which no solvent suitable for potentiometry is and precisely. The glass shaft lends the sensor an out-available standing resistance to many organic solvents and aggres- sive media. The Dosino technology The Dosino technology from Metrohm has set a new standard in volumetric titration. The dosing unit is mounted together with the motor drive and the reagent bottle, thus guaranteeing maximum precision with mini- mum space requirements. Catalyzed thermometric titration In the event of very low sample concentrations or with low molar reaction enthalpy, the temperature change during the titration is often not sufficient for unambig- uous determination of the endpoint, as for example with the determination of very small quantities of organic acids with the titrant c(KOH) = 0.1 mol/L in isopropanol. Here the addition of a small amount of paraformaldehyde facilitates the finding of the endpoint, because immedi- ately after the endpoint is reached (i.e. as soon as excess hydroxide ions are present), the base-catalyzed hydrolysis of the paraformaldehyde starts. This strongly endother-mic reaction now provides a sharp endpoint. Ordering Information 859 Titrotherm 2.859.1010 859 Titrotherm complete with tiamo™ 32 Potentiometric and thermometric titration Karl Fischer titration Karl Fischer titration 33 34 Karl Fischer titration Karl Fischer titration Introduction to Karl Fischer titration 36 Volumetric KF titrators 37 Volumetric KF titrators – Overview 37 890/901 Titrando 38 915 KF Ti-Touch 39 870 KF Titrino plus 40 KF Coulometer 41 Coulometric KF titrators – Overview 41 851/852 Titrando 42 756/831 KF Coulometer 43 899 Coulometer 44 Manual KF Sample Preparation 45 Polytron PT 1300 D 45 KF Evaporator 45 860 KF Thermoprep 45 Automated KF Sample Preparation 46 874 USB Oven Sample Processor 46 885 Compact Oven Sample Changer 47 KF Automation 48 Automated coulometric KF titrations 48 Automated volumetric KF titrations 48 Automated volumetric KF titration including sample preparation 48 KF Gas Analyzer 49 875 KF Gas Analyzer 49 Karl Fischer titration 35 Introduction to Karl Fischer titration Karl Fischer water determination is one of the world‘s For difficult samples, we offer you intelligent solutions most frequently applied laboratory methods. In contrast for sample preparation, e.g., the KF oven technique or to other water determinations, it is specific, rapid and sample pulverization with a homogenizer integrated in requires very little apparatus. the system. With an application range of 0.1% to 100% water, The use of automated systems pays off very quickly with volumetric Karl Fischer titration is used in a wide high numbers of samples. Metrohm KF Automation variety of industries. Volumetry has the advantage that offers you sophisticated techniques, not only for volu-not only liquid but also solid and pasty samples can be metric but also for coulometric KF titration. added directly to the titration vessel. No matter whether you would like to determine water in foods, cosmetics or pharmaceutical products, you can never go wrong with the Metrohm KF titrators. Coulometry is the optimum method for water determina- tion in liquids, solids and gases for water contents in the trace range (10 µg to 10 mg absolute water). In addition, coulometry is an absolute method and thus no titer determination is required. 36 Karl Fischer titration Volumetric KF titrators Volumetric KF titrators – Overview Technical specifications 870 KF 890 901 915 Ti-Touch Titrino plus Titrando Titrando Titration to preset pH/mV endpoints (SET) − − − yes pH calibration and pH measurements (CAL, MEAS) − − − yes Real-time curve display yes yes yes yes Predefined methods yes yes yes yes Parallel titration − − − yes (tiamoTM) Dosing Unit Dosing Unit Dosing drive for titration Exchange Unit (optional Exchange Exchange Unit (optional Exchange Unit) Unit) Inputs, interfaces Second, galvanically separated measuring interface − − − option Automated reagent exchange with Dosino (option) − yes − yes MSB-port for connection of further Dosinos (addition − 2 3 4 of auxiliary solution, …) MSB-port for connection of further Dosinos (Titration) − 2 − 4 Attachment of stirrer yes yes yes yes Internal stirrer and pump − yes − − Sample changer connection − yes yes yes Attachment of printer, balance, ... USB (1) USB (1) USB (2) USB (2) optional optional optional Optional interfaces Ethernet (RJ-45) RS 232C RS 232C RS 232C Software tiamo TM − − yes yes tiBase TM yes yes yes yes Touch Control − integrated Touch yes yes Control Karl Fischer titration 37 890/901 Titrando The KF titrators for the modern titration labora- 901 Titrando tory In addition to the Karl Fischer mode (KFT), the 901 Thanks to their simple and intuitive operation the KF Titrando is also equipped with the SET mode and can Titrandos are the optimum instruments not only for rou-thus perform titrations at a predefined endpoint. As a tine work but also for sophisticated applications in result of the high-resolution, galvanically isolated meas-the development laboratory. With the KF Titrando, uring interface with additional digital measuring input for you have a titration system that can adapt to all imagina-the intelligent „iTrodes“ electrodes, it is additionally pos-ble requirements and demands no compromises. sible to perform pH measurements with a maximum of precision. Thanks to the four MSB connectors, up to four An electrode test and the specially created „safety stop“ 800 Dosino dosing systems can be connected to the 901 parameter prevent cell overflows during conditioning, Titrando. These can be used not only for titration, but i.e. conditioning is stopped after a given time or after a also for the automated addition of sample, standard and given volume of KF reagent has been added (laboratory auxiliary solutions such as solubility promoters. Further-safety). The sophisticated control algorithm of the more, al Liquid Handling commands are available. Titrando is tailored to the characteristics of the Karl Thanks to its „Empty“ command, the Dosino may be Fischer reaction and guarantees maximum-precision completely emptied; this makes it possible to dispense results. with the tasks of opening and cleaning the dosing unit. The choice is up to you! Both the 901 Titrando and the 890 Titrando 890 Titrando can be optionally controlled either as stand-The 890 Titrando offers the same high-end features as alone systems with Touch Control or through the PC with the 901 Titrando (except for the digital measuring input), tiamo TM. but is restricted to the KF mode and titrates exclusively with the proven exchange unit. In addition, up to three 800 Dosino dosing systems can be connected and used for the automatic addition of sample, standard and aux- iliary solutions. Ordering Information 2.890.0110 890 Titrando with Touch Control 2.890.0210 890 Titrando with tiamo™ light 2.901.0010 901 Titrando Options 2.800.0010 800 Dosino 2.803.0010 803 TI Stand with stirrer and pump 2.900.0010 900 Touch Control 6.2061.010 Bottle holder for Dosinos 6.3026.150 Exchange Unit 5 mL 6.3026.210 Exchange Unit 10 mL 6.3026.220 Exchange Unit 20 mL 6.3032.120 Dosing Unit 2 mL 6.3032.150 Dosing Unit 5 mL 6.3032.210 Dosing Unit 10 mL 6.3032.220 Dosing Unit 20 mL 6.6056.241 tiamo™ 2.4 Light CD: 1 license 6.6056.242 tiamo™ 2.4 Full CD: 1 license 901 Titrando with 900 Touch Control 6.6056.243 tiamo™ 2.4 Multi CD: 3 licenses 38 Karl Fischer titration 915 KF Ti-Touch • Buret, stirrer, dosing unit, membrane pump and Touch Different reagents require different parameters. The 915 Control in a single compact unit KF Ti-Touch allows for the pertinent method to be select- • Contact-free reagent replacement ed for the different reagents. • Intranet and LIMS access – without PC • Generating PDF reports – without a PC Due to its simple and intuitive operation, it is the optimal • USB port for USB flash drive, printer, barcode reader, instrument for routine work. etc. • One-touch titration For example, the KF icons show you at a glance whether the instrument still needs to be conditioned or whether „Reduce to the max“ – that is the concept behind the you can start the water determination. The electrode test 915 KF Ti-Touch. The new compact titrator for Karl and the „safety stop“ parameter prevent cell run-over Fischer titration from Metrohm offers the maximum in during conditioning. If, for example, the electrode is not the class of stand-alone systems for routine analysis. connected correctly or the titration cell is very humid, conditioning is stopped automatically after a given time The sophisticated control algorithm of the 915 KF or after a given volume of KF reagent has been added. Ti-Touch is tailored to the characteristics of the Karl This function increases work safety in your laboratory. Fischer reaction and guarantees maximum-precision results. In addition, you can select a polarized alternating Automatic, contact-free reagent replacement current (Ipol) or a defined voltage (Upol) to be applied to Replacing the used KF reagent in the titration cell may be the electrode. Both working methods ensure fast, true carried out manually using the integrated membrane results. pump. Automated replacement is even more convenient. You determine the moment and the instrument performs the replacement automatically together with a Dosino. In both cases, contact with harmful reagents is avoided. The Dosino – the optimum KF dosing system Thanks to its „Empty“ command, the Dosino may be completely emptied; this makes it possible to eliminate the task of opening and cleaning the dosing unit, which is particularly annoying with KF reagents. Once the reagent is used up, the remaining content in the cylinder may be directly returned to the bottle or the titration vessel. Then the empty reagent bottle is replaced, the „preparing“ routine may be carried out via 915 KF Ti-Touch and the titer determination of the new reagent is ready to be started. In contrast to the exchange unit, repeated rinsing prior to titer determination is not necessary; this means you save on both time and reagents. Ordering Information 915 KF Ti-Touch 2.915.0110 915 KF Ti-Touch Karl Fischer titration 39 870 KF Titrino plus • Maximum ease of installation Maximum ease of installation • Uncomplicated operation thanks to predefined The installation of the 870 Titrino plus is designed to be methods and formulas exceptionally simple. Exchange unit, stirrer and USB com- • Maximum precision thanks to high-resolution measur- pact printer are detected and configured automatically as ing input soon as they are connected. • Live curve for detecting side reactions • Overflow protection for enhanced work safety Ready-to-use methods make work easier • USB interface for compact printer You need only decide whether you wish to carry out a titer, blank value or water content determination and The inexpensive 870 Titrino plus is a KF titrator for volu-then start the titration with the single press of a key. metric water content determination. With it, water con- Parameters need to be adjusted only in exceptional tents from a few ppm to 100% can be determined relia- cases. bly and precisely in solid, liquid and gaseous samples. With its new user interface, which is tailored to routine Mouse or keys – select your favorite! users, the 870 Titrino plus is so simple to operate that The 870 Titrino plus is the first titrator that can be con-only brief orientation periods are required. It is the ideal trolled either per mouseclick or keyboard. titrator for routine determinations, also because of its robustness. Titration vessel and electrode are included in Maximum precision the scope of delivery. Just as is the case with the high-end Titrando titrator, the 870 KF Titrino plus is equipped with a high-resolution measuring input that guarantees results with the greatest of precision. The live curve brings side reactions to light Metrohm KF titrators are standard-equipped with a live curve display. Side reactions can thus be recognized and suppressed in time. Great importance is placed on work safety in the handling of the harmful KF reagents. The overflow of iodine solution from the titration vessel is prevented by the „Conditioning options“ safety parameter. Optional: The 803 KF Titration Stand The 803 KF Titration Stand is used for stirring and for the replacement of the exhausted working medium. With the integrated pump it is possible to aspirate the titrated solution and to add new solvent without opening the cell. Ordering Information 2.870.0010 870 KF Titrino plus 2.870.1010 870 KF Titrino plus complete 2.870.1020 870 KF Titrino plus with printer 2.870.2010 870 KF Titrino plus and 860 KF 870 KF Titrino plus with 803 Ti Stand Thermoprep 40 Karl Fischer titration KF Coulometer Coulometric KF titrators – Overview Technical specifications 756 KF Coulometer 831 KF Coulometer 851 Titrando 852 Titrando 899 Coulometer Coulometric Karl Fischer titration (KFC) yes yes yes yes yes Volumetric Karl Fischer titration (KFT) − − − yes − Bromine index (BRC) − − yes yes − Titration to preset mV endpoints − − − yes − (MET Ipol, SET Upol) Monotonic equivalence point titration − − − yes − (MET Ipol, MET Upol) Water/time real-time curve display yes yes yes yes yes Predefined methods yes yes − − yes yes Parallel titration − − yes − (with tiamoTM) (with tiamoTM) Automatic reagent exchange with Dosino yes yes yes yes − (option) Automatic titration start for coulometry − − yes yes yes Inputs, interfaces MSB-port for connection of further Dosinos − − − 3 − (titration) MSB-port for connection of further Dosinos − − yes yes − (dosing) Attachment of stirrer yes yes yes yes yes Sample changer connection yes yes yes yes yes Attachment of printer and balance RS 232C RS 232C USB USB USB Optional interfaces RS 232C RS 232C RS 232C RS 232C RS 232C Software tiamo yes yes TM yes yes − (2.1 or higher) (2.1 or higher) tiBase TM − − yes yes yes Touch Control − − yes yes − Karl Fischer titration 41 851/852 Titrando Coulometry is the ideal method for water determination sample will be conditioned away and the measurement in liquids, solids and gases when it comes to water deter-will need to be repeated. This will no longer be a prob- mination in the trace range (10 µg to 10 mg absolute lem for you with the 851 Titrando or the 852 water). In addition, coulometry is an absolute method Titrando. The instrument starts the titration automati-and thus no titer determination is necessary. cally, as soon as the sample is added. This way, you save on reagents, sample and above all on precious time. Coulometric titrations are carried out easily and quickly with the 851 Titrando. The 852 Titrando controls not Coulometric and volumetric titrations only coulometric, but also volumetric Karl Fischer titra-Should the water content of the samples be too high for tion. coulometric determination, this will not be a problem for the 852 Titrando. This instrument can determine sam-Bromine index ples with water contents ranging from a few micrograms It is now possible to determine bromine indexes with the to contents of 100% without difficulty. 851 Titrando and the 852 Titrando. No additional accessory parts are required for the measurements. The conventional coulometric titration cell and the generator Ordering Information electrode with diaphragm can also be used for bromine 2.851.0010 851 Titrando with generator electrode index determination. Only the anolyte and catholyte with diaphragm need to be adapted. 2.851.0020 851 Titrando with Touch Control and generator electrode with diaphragm Automatic titration start 2.851.0110 851 Titrando with generator electrode It can readily happen that the sample is injected into the without diaphragm titration vessel without the titration having been started 2.851.0120 851 Titrando with Touch Control and beforehand. If this is the case, then the water in the generator electrode without diaphragm 2.852.0050 852 Titrando with generator electrode with diaphragm 2.852.0060 852 Titrando with Touch Control and generator electrode with diaphragm 2.852.0150 852 Titrando with generator electrode without diaphragm 2.852.0160 852 Titrando with Touch Control and generator electrode without diaphragm Options 2.800.0010 800 Dosino 2.801.0010 801 Stirrer 2.803.0010 803 TI Stand with stirrer and pump 2.900.0010 900 Touch Control 6.3032.120 Dosing Unit 2 mL 6.3032.150 Dosing Unit 5 mL 6.3032.210 Dosing Unit 10 mL 6.3032.220 Dosing Unit 20 mL 6.3032.250 Dosing Unit 50 mL 6.6056.241 tiamo™ 2.4 Light CD: 1 license 6.6056.242 tiamo™ 2.4 Full CD: 1 license 852 Titrando with 900 Touch Control 6.6056.243 tiamo™ 2.4 Multi CD: 3 licenses 42 Karl Fischer titration 756/831 KF Coulometer The Metrohm KF coulometers are suitable for precise Arguments that convince: water determination in the trace range (1 ppm to 10%). • Live curve for early detection of possible side reactions They come supplied with a selection of two different • Simple operation thanks to dialog in German, English, types of generator electrodes. The generator electrode French, Spanish, Italian, Portuguese and Swedish. without diaphragm requires only one reagent and is • Selection of Expert or Routine mode practically maintenance-free. The utilization of the gen- • Internal memory for up to 100 methods erator electrode with diaphragm is preferred for the fol- • With two RS-232C (DB9) data interfaces for connect- lowing applications: extremely low water content ing balance, printer and PC (<100 µg absolute water), utilization of ketone reagents • Optional connection for PC keyboard and barcode or of a high proportion of solubility promoter (>10%). reader • Optional: Automatic reagent replacement via dosing With or without a printer – The choice is up to you! The unit and Dosino 756 KF Coulometer comes equipped with a built-in ther- mal printer. You can, however, also connect an external printer or connect the instrument with a PC, just as you would with the 831 KF Coulometer. You receive a complete titration cell and extensive acces- sories with all KF coulometers. The 728 Stirrer (magnetic stirrer) is included in the accessories of the KF coulome- ters with generator electrodes with diaphragm. Ordering Information 2.756.0010 756 KF Coulometer with generator electrode with diaphragm 2.756.0110 756 KF Coulometer with generator electrode without diaphragm 2.831.0010 831 KF Coulometer with generator electrode with diaphragm 2.831.0110 831 KF Coulometer with generator electrode without diaphragm 2.831.2110 831 KF Coulometer and 860 KF Thermoprep Options 2.140.0200 Impact printer CUSTOM DP40-S4N 2.700.0020 700 Dosino 2.703.0010 703 Ti Stand with stirrer and pump 2.728.0010 728 Stirrer without stand 6.5617.000 Equipment for reagent replacement 756 KF Coulometer with 728 Stirrer Karl Fischer titration 43 899 Coulometer Small and compact Flexible, thanks to accumulator The 899 Coulometer is the smallest Metrohm coulome- A Power Box can be obtained as an optional accessory ter. The magnetic stirrer is already built-in and a support for the 899 Coulometer. This ensures impressive flexibility. rod can be dispensed with, thanks to the titration cell Determine the water content of your samples wherever holder. The titration cell stands securely attached on the you like. 899 Coulometer. Automatic titration start It can readily happen that the sample is added to the titration vessel without the titration having been started beforehand. In such cases, the conditioning continues to run until the reagent is once again titrated until it is dry. Recalculations are not possible and the determination must be repeated. This costs sample and valuable time. The 899 Coulometer offers an automatic titration start. The titration starts automatically, as soon as sample is added to the titration vessel. Ordering Information 2.899.0010 899 Coulometer with generator electrode with diaphragm 2.899.0110 899 Coulometer with generator electrode without diaphragm 2.899.1010 899 Coulometer with generator electrode with diaphragm and Neo‘s USB thermal printer 2.899.1110 899 Coulometer with generator electrode without diaphragm and Neo‘s USB thermal printer 2.899.2110 899 Coulometer with generator electrode without diaphragm and 860 KF Thermoprep 2.899.3110 899 Coulometer with generator electrode without diaphragm and 885 Compact Oven SC Options 2.141.0100 USB Thermal printer Neo‘s 6.2164.500 Power Box for 899 6.5406.000 Coulometric KF equipment, including generator electrode with diaphragm 6.5406.010 Coulometric KF equipment, including generator electrode without diaphragm 899 Coulometer 44 Karl Fischer titration Manual KF Sample Preparation Polytron PT 1300 D (2.136.0100) Polytron PT 1300 D - Metrohm version Homogenizer that can be controlled directly by tiamo™ or Touch Control. Polytron PT 1300 D KF Evaporator (2.136.0200) The KF Evaporator is used for sample preparation in Karl Fischer titration by means of azeotropic distillation. As with the oven method, the water is separated from KF the Evapor sample matrix. ator Because the sample itself remains in the evaporation chamber, the titration vessel and the electrodes are not contaminated. Furthermore, unwanted side reactions and matrix effects are avoided. 860 KF Thermoprep (2.860.0010) The 860 KF Thermoprep is designed for thermal sample preparation in Karl Fischer titration. Numerous substances cannot be analysed by direct Karl 860 Fischer KF titration Thermopr as they are not ep soluble, react with the Karl Fischer reagent or release their water only very slowly or not until heated to high temperatures. Using tightly sealed sample vials, the sample is inserted in the oven. The samples can be subsequently analysed by any volumetric or coulometric KF titrator. Karl Fischer titration 45 Automated KF Sample Preparation 874 USB Oven Sample Processor The 874 Oven Sample Processor opens up new possibili- Area of application ties for water content determinations in samples that The oven method is suitable for liquid and solid samples either are insoluble, cause side reactions or cannot be and can be used with both volumetric and coulometric introduced directly into the titration vessel for other rea-KF titrators. sons. These problems are avoided with the use of the oven method, because the water is separated from the The advantages of the oven method at a glance difficult sample matrix. • Reproducible analysis conditions for all samples, reflected in a markedly improved precision in the results Mode of operation of the oven technique • Reduction of manual sample preparation to a mini-Each of the samples is introduced into the oven in tightly mum sealed sample vials. The water is released by the heating • Considerable time savings up of the sample and transferred into the KF cell with a • No contamination of the oven or of the KF cell by the flow of carrier gas. It is there that the Karl Fischer titration sample, thus precluding any carry-over or memory then takes place. effects • Improved release of water from the sample, because Sample preparation the carrier gas is not channeled over the sample, but Sample preparation for the oven technique is as simple rather directly through it as possible and consists solely of weighing the sample • Lower reagent consumption, as the titration solution into the vial and then sealing it. In addition, the hermetic needs to be replaced only rarely sealing of the vessels with septa reliably prevents the absorption of humidity from the ambient air. 874 USB Oven Sample Processor • USB device – the 874 USB Oven Sample Processor is simply connected to a PC via USB port and recognized automatically. • Optimum heating-up temperature – with the help of the temperature ramp, the optimum oven temperature can be determined for each sample. • Reagent replacement – a 800 Dosino can be connect- ed directly to an MSB connector of the changer and used together with a dosing unit for automatic re- placement of the reagent. Including tiamo TM full and extensive accessories, comprising 100 sample vessels, 100 septum caps, 1 pair of sealing pliers. Ordering Information 2.874.0010 874 USB Oven Sample Processor with tiamo™ full 2.874.0020 874 USB Oven Sample Processor customized with tiamo™ full Options 6.1448.050 Aluminum septum caps 874 USB Oven Sample Processor with 851 Titrando 6.2419.000 Sample glass, 6 mL, 1,000 pcs. 46 Karl Fischer titration 885 Compact Oven Sample Changer • Small space requirements – The instrument offers The substance to be analyzed is placed in a tightly sealed automation in the smallest possible space. sample vessel on the sample rack and heated up in the • Flexibility – The 885 Compact Oven Sample Changer oven. A double needle pierces the septum and a dry flow can be operated with a coulometric or volumetric of carrier gas transports the released water into the titra-titrator. tion cell. • Simple operation – Only the oven temperature, the gas flow and the number of samples must be defined. The advantage of the oven method lies in the fact that • Reusable sample vessels – After the analysis, sample the sample itself does not enter the titration cell. This vessels can be opened, cleaned and reused. avoids the contamination of both the oven and titration cell, thus excluding both carry-over and memory effects The 885 Compact Oven Sample Changer is used for that could falsify the results of the analysis. thermal sample preparation in Karl Fischer titration. The samples are heated in the oven to a temperature of up Small space requirements to 250 °C. This causes the water to vaporize and be The name of the 885 Compact Oven Sample Changer transported with a dry carrier gas into a titration cell in explains its purpose: The instrument offers automation in which the analysis takes place. a minimum amount of space. Area of application and principle of the oven Great flexibility method Depending on the sample, Karl Fischer titration can be The oven method is recommended for samples that either coulometric or volumetric. No matter which release their water only at higher temperatures, for poor-method is used – the 885 Compact Oven Sample ly soluble substances and those that react with the KF Changer can be operated with all stand-alone KF titrators reagent. with sample table. Simple operation The instrument is controlled using the integrated keypad. Only the oven temperature and the gas flow must be defined and the number of the samples to be determined must be established. Reusable sample vessels Screw-cap vials are used with the 885 Compact Oven Sample Changer. After the measurement, these sample vessels can be opened, cleaned and subsequently reused without difficulty. Only the septum must be replaced after it has been pierced. Ordering Information 2.885.0010 885 Compact Oven Sample Changer Options 6.1448.077 Septum 6.2141.340 Remote cable 885 - Remote Box MSB 885 Compact Oven Sample Changer 6.2148.010 Remote Box MSB Karl Fischer titration 47 KF Automation Automated coulometric KF titrations (MATi 04) MATi 4 is a fully automated system for coulometric Karl Fischer titrations with high sample throughput. Up to 160 samples in 6 mL vials can be placed on the sample Automated rack of the Sample Pr coulometric ocessor. The sample is pipetted into an external coulometric cell and then titrated there. The KF titr system is ations controlled by means of the tiamo™ titration software. Automated volumetric KF titrations (MATi 10) Fully automated system for volumetric Karl Fischer water content determination in up to 24 samples. The system is controlled with tiamo™ and consists of an 814 USB Automated Sample Processor, a 901 volumetric Titrando and extensive KF accesso- ries. The samples are weighed out into the beakers, titrations sealed to protect against humidity and placed on the rack. Before the actual titration, they are dissolved in a KF working medium, after which the water content is titrated. Automated volumetric KF titration including sample preparation (MATi 11) Fully automated system for volumetric Karl Fischer water content determination in up to 53 samples. This system Automated is controlled with volumetric tiamo™ and consists of KF an 815 Robotic USB Sample Processor XL, a 901 Titrando and titration extensive including accessories. The samples ar sample e pulverized in a short time with the Polytron and the water they contain pr is r epar eleased. ation Even samples of poor solubility, e.g., tablets, can be analyzed without difficulty with this method. The use of solubility promoters can be avoided in this way. 48 Karl Fischer titration KF Gas Analyzer 875 KF Gas Analyzer • Complete system with durable components for high The system was designed for water content determination flexibility and for pressures up to 40 bar in gases in accordance with Karl Fischer and is also suita- • Separation of the gas-carrying system from the elec-ble for very low water content determinations. tronics and the power supply • Input filter for avoiding the introduction of particles by Application examples the sample Water content determination in various liquefied gases • Integrated vaporizer for liquefied gases • Propane, propene, LPG, butane, butene, butadiene • Oil filter for removing oil residue • Dimethyl ether • Precise gas measurement with mass flow measure- • Methyl chloride, ethyl chloride, vinyl chloride ment instrument • CFC, HFC, CHC, fresh and used refrigerants with chiller • Automated analysis process oil contents • Predefined analysis methods • All components are integrated in a single housing Water content determination in permanent gases such as natural gas The KF Gas Analyzer is a robustly constructed analysis system for routine water content determination in liquefied and permanent gases. The system is controlled with tiamo™ and is comprised of one operating unit (TFT monitor) and an analysis module. The analysis module is fitted with the gas path, a titration vessel and a coulometer. This makes it possible to perform all analysis steps fully automatically. Ordering Information 2.875.9020 KF Gas Analyzer with TFT monitor 2.875.9050 KF Gas Analyzer without TFT monitor Options 6.7209.000 KF Gas Analyzer equipment for reagent replacement and adding methanol 6.7209.010 KF Gas Analyzer equipment for rinsing 875 KF Gas Analyzer with solvent Karl Fischer titration 49 Dosing devices Dosing devices 51 52 Dosing devices Dosing devices Dosing, pipetting and manual titration 54 The Dosimats at a glance 54 865 Dosimat plus 55 876 Dosimat plus – 876 Manual Titrator 56 Intelligent Liquid Handling 57 846 Dosing Interface 57 Dosing devices 53 Dosing, pipetting and manual titration The Dosimats at a glance 876 Dosimat plus 876 Manual Titrator plus 865 Dosimat plus Steps per cylinder volume 10 000 Pulses 10 000 Pulses 10 000 Pulses Printer connection (USB) yes yes yes Remote Interface yes yes yes Balance Connection via RS232 yes (6.2148.030) yes (6.2148.030) yes (6.2148.030) Intelligent Exchange unit yes yes yes Push Button Cable yes yes yes Manual Dosing (DOS) yes yes yes Manual Titration yes yes yes Extended Dosing (XDOS) yes yes yes Content Dosing (CNT D) − − yes Liquid Transfer (LQT) − − yes Tandem Dosing (with 805 Dosimat) yes yes yes Including 801 Magnetic Stirrer and Stand optional yes optional Remote Control via PC yes yes yes 54 Dosing devices 865 Dosimat plus Universal dispensing unit for titration and dosing tasks in XDOS (Extended Dosing) the laboratory. Including push-button cable for manual Fixed volume dosing: The volume and the dosing rate are dispensing control and 6.3026.220 exchange unit specified. (20 mL). Time-controlled dosing: The volume and the time are A multitude of instruments can be connected at the USB specified. interface of the Dosimat plus, even a number of them simultaneously when a USB hub is used (keyboard, Dosing according to dosing rate: The dosing rate and the mouse, USB compact printer or USB DIN A4 printer, USB time are specified. Memory Stick for methods and data backup). The op- tional 6.2148.030 USB/RS-232 adapter box enables the If continuous dosing without interruption is required, connection of laboratory balances and operation with a then the 865 Dosimat plus can be operated together computer. with an 805 Dosimat in tandem mode. With its four dosing modes, the Dosimat plus offers a CNT D (Content dosing) multitude of applications: This mode is suitable for the preparation of standard and other solutions. The 865 Dosimat plus automatically DOS (Dosing) determines the volume of the solvent to be dosed on the Dosing at the press of a button, particularly suitable for basis of the sample size of the starting substance (solid performing manual titrations with indicator. A result can or stock solution) and the specified target concentration. be calculated automatically from the dosed volume and A report containing all of the relevant data concerning a result report can be printed out. Different calculation the solution that was prepared can be printed out after variables can be defined in advance as parameters. the dosing. LQT (Liquid transfer) This mode is suitable for the pipetting and diluting of liquids. Ordering Information 865 Dosimat plus with 801 Magnetic Stirrer (optional) 2.865.0010 865 Dosimat plus Dosing devices 55 876 Dosimat plus – 876 Manual Titrator Metrohm Dosimats make routine Liquid Handling easier. for methods and data backup). The optional 6.2148.030 They are used to accomplish a wide variety of dosing and USB/RS-232 adapter box enables the connection of labo-Liquid Handling tasks in laboratories around the world. ratory balances and remote control with a PC. With its The new Dosimats can be used as autonomous, manu-two dosing modes, the Dosimat plus and the Manual ally operated instruments or they are used as automatic Titrator are outstandingly suitable for classic laboratory dosing devices for Titrino/Titrino plus titrators. dosing tasks. The 876 Dosimat plus is suitable for hand titrations and DOS (Dosing) dosings. A push-button cable for manual dispensing Dosing at the press of a button, particularly suitable for control and a 20 mL exchange unit are supplied with the performing manual titrations with indicator. A result can Dosimat plus. be calculated automatically from the dosed volume and a result report can be printed out. Different calculation The 876 Manual Titrator with flat stopcock switching and variables can be defined in advance as parameters. refilling is used for result calculations for titration with color indicator. The instrument is also supplied with a XDOS (Extended Dosing) push-button cable for manual dispensing control, a Fixed volume dosing: The volume and the dosing rate are 20 mL exchange unit and a magnetic stirrer. specified. A multitude of instruments can be connected at the USB Time-controlled dosing: The volume and the time are interface of the Dosimat plus and Manual Titrator, even specified. a number of them simultaneously when a USB hub is used (keyboard, mouse, USB compact printer or com-Dosing according to dosing rate: The dosing rate and the mercially available USB DIN A4 printer, USB Memory Stick time are specified. If continuous dosing without interruption is required, then the 876 Dosimat plus can be operated together with an 805 Dosimat in tandem mode. Ordering Information 2.876.0010 876 Dosimat plus 2.876.0110 876 Manual Titrator plus Options 2.801.0040 801 Stirrer with stand 2.802.0040 802 Stirrer (propeller stirrer) for 804 Ti Stand 2.804.0010 804 Ti Stand without stand rod 2.804.0040 804 Ti Stand with stand 2.805.0010 805 Dosimat 6.3026.110 Exchange Unit 1 mL 6.3026.150 Exchange Unit 5 mL 6.3026.210 Exchange Unit 10 mL 6.3026.220 Exchange Unit 20 mL 876 Manual Titrator 6.3026.250 Exchange unit 50 mL 56 Dosing devices Intelligent Liquid Handling 846 Dosing Interface The 846 Dosing Interface can be seamlessly incorporated The control device has four MSB connectors (MSB = as a system component and control instrument into a Metrohm Serial Bus) at which auxiliary and peripheral Metrohm Titrando system. The interface is operated with devices can be operated. Numbered among these are a Touch Control or from a PC with tiamo™. one dosing drive each (800 Dosino or 805 Dosimat), one stirrer or titration stand, one Remote Box, etc. Two USB Comprehensive Liquid Handling connectors continue to be available through which such Basic operations of everyday laboratory work such as instruments as printer, balances, keyboard, barcode pipetting, transferring, dosing, dispensing and diluting reader, a USB Sample Processor or other control devices become child‘s play thanks to the innovative Liquid can be connected. Handling functionality of the Dosing Interface in connec- tion with the 800 Dosino. The system guarantees maxi- mum accuracy and precision in the range of 10 µL to 100 mL, i.e. across no fewer than four orders of magnitude. Ordering Information 2.846.0010 846 Dosing Interface 2.800.0010 800 Dosino Options 2.801.0040 801 Stirrer with stand 6.2061.010 Bottle holder for Dosinos 6.2065.000 Stacking frame for 846 Dosing Interface, 856 Conductivity Module, 867 pH Module 6.3032.120 Dosing Unit 2 mL 6.3032.150 Dosing Unit 5 mL 6.3032.210 Dosing Unit 10 mL 6.3032.220 Dosing Unit 20 mL 846 Dosing Interface with 900 Touch Control 6.3032.250 Dosing Unit 50 mL Dosing devices 57 Automation in titration Automation in titration 59 60 Automation in titration Automation in titration Introduction to automation 62 Automation peripheral devices 80 Automation in titration 62 Membrane pumps 80 Overview of sample changers 63 Peristaltic pumps 81 849 Level Control 82 Sample Changer 64 731 Relay Box 83 869 Compact Sample Changer 64 786 Swing Head 84 898 XYZ Sample Changer 65 741 Magnetic Stirrer 85 802 Stirrer 85 USB Sample Processors 66 814 USB Sample Processor 66 815 Robotic USB Sample Processor XL 67 864 Robotic Balance Sample Processor TAN/TBN 68 Titrosampler 69 862 Compact Titrosampler 69 855 Robotic Titrosampler 70 Titration systems 71 Introduction – Automated systems 71 848 Titropackage plus 72 MATi systems 73 Fully automatic water analysis 73 Automated TAN/TBN analysis 73 Nonaqueous titrations 73 Automatic titration of acids and bases for up to 12 samples 73 Automated titration system for up to 28 samples 74 Automated pipetting and titration system for up to 100 samples 74 Automated COD determination 74 Fully automated determination of the permanganate index, according to DIN EN ISO 8467 74 862 Compact Titrosampler 75 Robotic Analyzer packages 76 Robotic Chloride Analyzer 76 Robotic Acid-Base Analyzer 76 Robotic TAN/TBN Analyzer 76 Robotic Fluoride Analyzer 76 Robotic Transfer Analyzer 77 Sample preparation systems 78 An overview of sample preparation 78 Robotic Soliprep 79 Automation in titration 61 Introduction to automation Automation in titration The automation of potentiometric measurement methods has gained enormously in importance as it becomes ever less frequently the case that simple deter- minations are sufficient. In contrast to purely manual determination, the fully automatic alternative is very precise, safe and time-saving. With large numbers of samples, the thought of auto- mation of the analysis that is always the same quickly presents itself, particularly since qualified personnel can be utilized more efficiently when the routine is taken over by a completely automated system. Even in the case of smaller series or with many different analyses, automation can help achieve more rapid and more reproducible results. A uniform sample preparation that can be guaranteed only with a completely automated system ensures that the results will continue to be identical – independent of the user – even over long periods of time. Typical preparatory steps from everyday lab work such as Liquid Hand- ling (pipetting, transferring), dilution, addition, temper-ing, degassing, pulverization, filtration, filling and much more can proceed just as automatically as the subsequent analytical determination. One aspect not to be neglected is that of safety in the laboratory. The frequent handling of typical laboratory equipment (pipettes, burets, etc.) and the exposure to aggressive chemicals requires the complete concentration of the laboratory employee. When automated systems are used with sample preparation, the contact with hazardous substances and solvents is minimized, thus massively enhancing occupational safety. Metrohm offers a large selection of instruments for the automation of your analysis, including sample preparation. On the following pages, you will learn more about the various sample changers and the completely preconfigured analysis systems. 62 Automation in titration Overview of sample changers 862 869 814 815 Robotic 855 864 Compact Compact USB Sample USB Sample Robotic Robotic Balance Titrosampler Sample Changer Processor Processor XL Titrosampler Sample Processor Integrated measuring input yes − − − yes − Integrated balance − − − − − yes Work stations 1 1 1 / 2 1 / 2 1 2 Automatic rack recognition yes yes yes yes yes yes Exchangeable racks − − yes yes yes yes Titration / measurement directly on the rack yes yes yes yes yes yes 28 x 250 mL 28 x 250 mL 12 x 250 mL 28 x 200 mL 28 x 200 mL 34 x 150 mL 34 x 150 mL Standard racks 11 x 120 mL 11 x 120 mL 14 x 200 mL 16 x 150 mL 59 x 120 mL 59 x 120 mL 20 x 120 mL 22 x 120 mL 100 x 75 mL 100 x 75 mL 24 x 075 mL 160 x 6 mL 160 x 11 mL 228 x 11 mL 228 x 11 mL Thermostated racks − − − yes yes − Beaker sensor − − yes yes yes yes Splash protection yes yes yes yes yes yes Drip pan − − yes yes yes yes Max. number internal pumps − − 2 / 4 2 / 4 2 − Max. number external pumps 2 2 2 / 4 2 / 4 1 4 Connector Swing Head − − 1 / 2 1 / 2 1 2 External positions − − 4 / 8 4 / 8 4 8 Pipetting / Sample transfer − − yes yes yes yes Stirrer connector 1 1 1 / 2 1 / 2 1 2 Connector MSB − − 3 3 3 3 Connector Remote yes yes optional optional optional optional Connector USB − − 2 2 2 2 Connector Mini-USB yes yes − − − − Stand-alone yes yes optional optional optional − tiamo™ − − yes yes yes yes Automation in titration 63 Sample Changer 869 Compact Sample Changer • Inexpensive automation Thanks to the large and clearly organized live display, • Space-saving the current status of the sample series can be recognized • Various method templates directly and important samples can be given preferential • Simple operation analysis at any time. In light of the fact that laboratory • A total of 12 positions space is expensive and rare, the compact sample changer • Live display requires no more support surface than that of a commer- cially available laboratory balance. The 869 Compact Sample Changer offers automation in a minimum amount of space. Various method templates can be used as the basis for creating and storing application-specific methods. Only The 869 Compact Sample Changer offers the rapid and four parameters need to be set on the 869 Compact simple automation of Titrino and Titrino plus applica-Sample Changer for this purpose. In addition, the tions. For multiple determinations and small sample methods can also be printed out or saved electronically series, this sample changer is just the right choice. A via USB (OTG) connector. Communication between Com-wide variety of titrations can be performed fully auto-pact Sample Changer and Titrino / Titrino plus takes place matically in a total of 12 positions and the electrode can via remote signals with an additional control box or PC be cleaned and/or conditioned between the determina- being required. tions. In order to keep the consumption of titrant and solvents as low as possible, slender sample beakers are The titration head of the sample changer offers space for used as standard equipment that enable low-waste and an 802 Stirrer propel er stirrer and two additional rapid titration with even small volumes. electrodes. The propeller stirrer can be connected directly to the instrument and is also monitored by it. Titrant and auxiliary reagent can be added with the buret tips that have already been inserted. The 869 Compact Sample Changer can be equipped with rinsing and aspiration pumps upon request. Despite its inexpensive price, no corners were cut with respect to safety with the 869 Compact Sample Changer. The safety shield protects the user against inadvertent contact with chemicals. Ordering Information 869 Compact Sample Changer 2.869.0010 869 Compact Sample Changer 64 Automation in titration 898 XYZ Sample Changer • Simple automation for high numbers of samples The 898 XYZ Sample Changer convinces with its speed • Time savings thanks to high speed and the number of samples that can be processed • Measuring and titration directly in the sample beaker without supervision. Two sample racks with 41 x 120 mL • Precise and reproducible results beakers or 24 x 250 mL beakers each can be fitted on the 898 XYZ SC and processed continuously there. As soon XYZ Sample Changer with one workstation, one mem- as the processing of the first sample rack has been com- brane pump and rinsing station for the automatic proc- pleted, it can be replaced while operations are running. essing of routine samples in large numbers. The control takes place via computer operation using the tiamo™ Whereas beakers, sample racks, titration head and titration software. tubing are already included in the package, stirrers, pro- peller stirrers and Ti Stand (if needed) must be ordered Time savings and improved operating sequences separately in accordance with the titrator. The advantages of a sample changer lie not only in the time savings for the laboratory personnel: Automatic systems control operating sequences, prevent errors and thus improve reproducibility and accuracy. Independent of the time of day, the system works through the prepared samples (automatic sample preparation, Liquid Handling or sample processing) and guarantees thereby the complete traceability of the individual steps. Ordering Information 2.898.0110 898 XYZ Sample Changer 82 x 120 mL 898 XYZ Sample Changer 2.898.0210 898 XYZ Sample Changer 48 x 250 mL Automation in titration 65 USB Sample Processors 814 USB Sample Processor In today‘s world, single determinations are simply no Thanks to its compact design, even complex tasks can be longer enough! carried out reliably on the smallest possible footprint. Depending on the sample matrix, the titrated sample In modern-day laboratories single determinations no solution is aspirated and the titration equipment is longer meet the requirements. Each and every result has rinsed using membrane or peristaltic pumps. These to be confirmed by multiple determinations in order to are either mounted already inside the instrument or meet the tough quality standards. An „automatic“ available as peripheral devices. titrator without sample changer is therefore basically just a semiautomatic titrator because it is not able to carry Depending on the user‘s preference, the 814 USB out a double or threefold determination by itself: each Sample Processor can be controlled by Touch Control, titration requires the user to take action, which is both the tiamo TM titration or the MagIC Net chromatography tedious and time-consuming. software. The method examples provided make creating your own methods perfectly easy. The benefits of a sample changer are not just found in the time saved by lab personnel: automated systems control operation sequences and thus improve reproducibility and accuracy. Errors can be reduced to a minimum. The system processes the prepared samples irrespective of the time of day. No matter whether auto- matic sample preparation, liquid handling or sample processing - the 814 USB Sample Processor masters eve- rything that used to be the exclusive domain of laboratory robots. Ordering Information 2.814.0010 814 USB Sample Processor (1T/1P) 2.814.0020 814 USB Sample Processor (1T/2P) 2.814.0030 814 USB Sample Processor (1T/0P) 2.814.0110 814 USB Sample Processor (2T/2P) 2.814.0120 814 USB Sample Processor (2T/4P) 814 USB Sample Processor with sample rack for 12 x 250 mL 2.814.0130 814 USB Sample Processor (2T/0P) 66 Automation in titration 815 Robotic USB Sample Processor XL Minimum effort with maximum sample throughput! tioned on the rack, so that series as large as possible can be processed. Depending on the application and the In view of the large number of samples and ever more vessel size used, this maximum is between 28 and 228 elaborate preparation steps, the use of robots is becom- positions (standard racks). ing ever more important, even in analytical laboratories. The larger the number of steps per sample that must be Thanks to the compact design, even more complex tasks completed, the more their professional automation pays can be managed reliably. Parallel processing of the off. It has been a long time since this merely involved samples is accomplished easily and conveniently with the switching from one beaker to the next in order to Robotic Sample Processor XL. While the pipetted sample analyze the sample – more and more it is the simplifi-volume is titrated at an external workstation (optional), cation of the entire sample processing, from the the pH of the prepared samples can also be determined, preparation to the multiple determination, that is de-for example, or the next sample can already undergo manded. preparation. This means the time per analysis is reduced to a minimum. Reproducibility and accuracy are the alpha and omega in analysis and are thus numbered among the main require- Depending on the requirements, the 815 Robotic USB ments of automation. Robotic Sample Processors make Sample Processor XL can be operated using Touch child‘s play of the basic operations of modern automation, Control, the tiamo TM titration software or the MagIC e.g., pipetting, transferring, aliquoting, dosing and Net chromatography software. Method development is dispensing. child‘s play with the example methods supplied. The use of the 786 Swing Head ensures that a maximum number of sample vessels can always be posi- Ordering Information 2.815.0010 815 Robotic USB Sample Processor XL (1T/1P) 2.815.0020 815 Robotic USB Sample Processor XL (1T/2P) 2.815.0030 815 Robotic USB Sample Processor XL (1T/0P) 2.815.0110 815 Robotic USB Sample Processor XL (2T/2P) 2.815.0120 815 Robotic USB Sample Processor XL (2T/4P) 2.815.0130 815 Robotic USB Sample Processor XL 815 Robotic USB Sample Processor XL (2T/0P) Automation in titration 67 864 Robotic Balance Sample Processor TAN/TBN • Fully automatic weighing of the sample The 864 Robotic Balance Sample Processor TAN/TBN • High-end analyzer with a minimum footprint offers fast and convenient sample preparation combined • Robotic USB Sample Processor - proven technology with the analysis of petrochemical products in one • Sample preparation and analysis in one system system. • Saves time by taking over routine tasks • Intelligent liquid handling - transferring, diluting and The sample is placed in a beaker on the sample rack and more an aliquote of it is pipetted and weighed into the titration • Reliable, robust and safe beaker ful y automatical y. After sample transfer • Attractive price and weighing, the sample is diluted with solvent. The • Control software that leaves nothing to be desired TAN or TBN value is then determined by titration. After the analysis the titration beaker is emptied and the titra-System for the fully automatic preparation and analysis of tion equipment is cleaned directly inside the beaker. petrochemical products that need to be weighed in, diluted and titrated. The sample rack can accommodate 20 sample and titra- tion beakers (6.1459.300) each as well as 20 pipetting System includes the following instruments: tips (6.1562.240) for sample transfer. These 10 mL tips are picked up, filled and stripped off after weighing so 1 x 864 Robotic Balance Sample Processor XL that cross-contamination-free sample transfer is 1 x 905 Titrando absolutely guaranteed. Time and amount of work per 3 x 800 Dosino sample is minimized. The only thing that needs to be 1 x 786 Swing Head ensured is that enough sample is in the beaker. 1 x 786 Swing Head strengthened 1 x 802 Stirrer The combined automation of sample preparation and 1 x 843 Pump Station (Peristaltic) analysis in a single system increases reproducibility and accuracy of results as the sample is weighed in where it will be analysed. If necessary, the equipment can be cleaned more intensely by using an additional external rinsing station combined with a second 843 Pump Station. The complete preparation and analysis system is controlled by the approved titration software tiamo™. Each preparation step (including the sample amount weighed in) is documented in a database as are the titration results for each single sample. Ordering Information 864 Robotic Balance Sample Processor TAN/TBN 2.864.1130 864 Robotic Balance Sample Processor TAN/TBN 68 Automation in titration Titrosampler 862 Compact Titrosampler The 862 Compact Titrosampler – titrator and sample tude of instruments can be connected to the USB inter-changer in one – is a completely automated titration face of the Compact Titrosampler, even a number of station with the support surface of a commercially availa-them at once when a USB hub is used: ble analytical balance. • Numerical keypad A wide variety of analyses can be performed fully auto- • USB compact printer matically in a total of 12 positions and the electrodes can • Commercially available USB DIN A4 printer be cleaned and/or conditioned between the determina- • USB Memory Stick for methods and data backup tions. The titration curve is directly in view thanks to the large, clearly organized Live Display and the current status of the sample series is recognizable at once. Pressing samples can be given priority analysis at any time. „Plug & Play“ functionality of intelligent dosing unit, stirrer and USB printer, a high-precision measuring input, operation per mouse click and a variety of dialog options – this combination device leaves nothing to be wished for. Highest degree of precision thanks to the new measuring input: Just as is the case with the high-end Titrando titrator, the new Compact Titrosampler is also equipped with a high-resolution measuring input which guarantees results with the greatest of precision. A multi-Ordering Information 2.862.0010 862 Compact Titrosampler 862 Compact Titrosampler with printer 2.862.0110 862 Compact Titrosampler with printer Automation in titration 69 855 Robotic Titrosampler The most discrete titrator in the world – invisible and yet A high-performance titrator based on the proven so flexible. Titrando technology is already integrated in the Robotic Titrosampler. With the accuracy and precision The 855 Robotic Titrosampler opens up a new dimension of the Titrando, the Robotic Titrosampler is also equipped in automation. The successful combination of high-with the STAT mode in addition to the usual titration performance titrator and perfect laboratory automation modes. Dynamic (DET) and monotonic (MET) titration, at the robot level covers an extensive spectrum of appli-endpoint titration (SET), enzymatic and pH-Stat titration cations. Thanks to this combination of automation and (STAT), measurement with ion-selective electrodes (MEAS titration, up to 40% of the space usually required can be CONC) and Liquid Handling (LQH, DOS) are child‘s play dispensed with – and this with identical functionality and with the Robotic Titrosampler. unchanging flexibility. With the multitude of combination options and in view The more demanding the application, the more work of the many different applications that are processed steps there are that are required prior to the actual deter-nowadays in laboratories, it is imperative that the mination. The time-consuming sample preparation retraceability of each individual sample be guaranteed. can be left to the Robotic Titrosampler. Whether it be With its connectors for intelligent dosing units, the 855 pipetting, transferring or simply diluting with solvent – Robotic Titrosampler offers complete documentation there is practically no limit to what is possible. With up to of your analysis. three buret connections integrated in the instrument, the Robotic Titrosampler offers sufficient latitude for Liquid The control can be accomplished either using the handy Handling tasks. Touch Control or with the state-of-the-art tiamo TM titration software. Ordering Information 2.855.0010 855 Robotic Titrosampler „Basic“ (1T/1P) 2.855.0020 855 Robotic Titrosampler „Basic“ 855 Robotic Titrosampler „Basic“ (1T/2P) 70 Automation in titration Titration systems Introduction – Automated systems Profit from more than 60 years of experience! Metrohm offers much more than only a wide variety of different individual instruments out of which you can select according to your requirements. Complete systems have been assembled on the basis of the application experiences of the last 60 years that are targeted to fulfil various requirements. Select your automated Metrohm laboratory instruments quickly and easily – with the assurance that we have already thought of everything. 848 Titropackage plus The compact and inexpensive system for the automation of potentiometric analyses in the smallest possible space! The combination of routine titrator and very compact sample changer requires exceptionally little space and can be put into operation in a very small amount of time. MATi systems These systems (MATi = Metrohm Automated Titration) are tailored to various standard applications and offer a maximum of convenience and flexibility. More than ten different, fully automated systems offer the perfect basis for the determination of your samples. Compact Titrosampler packages The Compact Titrosampler packages each covers one standard application – and that with minimum space requirements. The „Food/Beverage“ and „Salt“ packages are furnished with the accessories required for the appli- cation, so that you can begin working immediately. Just install and go. Robotic Analyzers The Robotic Analyzer family is comprised of various packages, each of which covers a standard application. Each of these packages offers you the perfect framework for the solution of your application. The centerpiece is always the unique 855 Robotic Titrosampler, the space-saving combination of a titrator installed in the sample changer. Depending on the application, this titrating analyzer is equipped with the accessories tailored to your application. You receive exactly what you need, no more and no less. Because of the great flexibility of Metrohm automation, the systems can be adapted and expanded according to customer specifications upon request. Automation in titration 71 848 Titropackage plus Compact and inexpensive system for the automation of dialog, which is tailored to routine users, the Titrino plus potentiometric determinations in the smallest possible instruments are so simple to operate that only brief space. Comprised of: orientation periods are required. Their robustness also makes them the ideal titrators for routine determinations • 1 x 848 Titrino plus in everyday laboratory operations. • 1 x 802 Stirrer • 1 x 869 Compact Sample Changer Compact Sample Changer For multiple determinations and small sample series, this The 848 Titropackage plus contains everything required sample changer is just the right choice. A wide variety of to enable rapid installation and direct entry into working titrations can be performed fully automatically in a total with the system. A large number of pre-defined titration of 12 positions and the electrode can be cleaned and/or methods, combined with very simple operation, permits conditioned between the determinations. In order to immediate use. keep the consumption of titrant and solvents as low as possible, slender sample beakers are used as standard Titrino plus equipment that enable low-waste and rapid titration The Titrino plus, Metrohm‘s new entry class in the area with even small volumes. Thanks to the large and clearly of potentiometric titration, is particularly attractive due organized live display, the current status of the sample to its practically unbelievable price-performance ratio. A series can be recognized directly and important samples large live display with titration curve, „Plug & Play“ func-can be given preferential analysis at any time. In light of tionality of exchange unit, stirrer and USB printer, a high-the fact that laboratory space is expensive and rare, the precision measuring input, operation per mouseclick – compact sample changer requires no more support sur-the Titrino plus offers considerably more than you would face than that of a commercially available laboratory ever expect in this price segment. With its operating balance. Ordering Information 2.848.0110 848 Titropackage plus 848 Titropackage plus 2.848.0120 Titropackage plus with printer 72 Automation in titration MATi systems Fully automatic water analysis (MATi 01) PC-controlled, fully automatic water analysis system with a rapid measurement system for the precise sample transfer of 100 mL samples. After the conductivity meas- Furully ement, automatic pH value, alkalinity water and Ca/Mg content are determined in an external cell. Up to 59 samples can be analysis placed on the rack. The control of this system is handled by the proven tiamo™ titration software. Automated TAN/TBN analysis (MATi 02) PC-controlled, fully automatic analysis system for the direct determination of TAN or TBN values in mineral oil products in series of up to 59 samples. The analysis is Automated carried out in accor T dance AN/TBN with ASTM ana standards - D664 and D2896. The system is noteworthy for its special resis- lysis tance to the solvents used in these applications. The data acquisition and the complete control of the system takes place via the proven tiamo™ titration software. Nonaqueous titrations (MATi 03) Direct nonaqueous titration of pharmaceutical active ingredients and other substances in series of up to 59 samples. The system is noteworthy for its special resis-Nonaqueous tance to organic solvents. titr The ations control of this system is handled by the proven tiamo™ titration software, that can also be provided in an FDA-compliant version upon request. Automatic titration of acids and bases for up to 12 samples (MATi 06) Fully automatic system for potentiometric titration of acids and bases in series of up to 12 samples. The titra-Automatic tion is carried out dir titr ectly ation in the of beaker on the rack. Afterwards, the electrode is cleaned automatically using acids the membr and ane bases pumps built into for the up sample to changer and the titration beaker is emptied. The control of this system 12 is samples handled by the user-friendly tiamo™ titration software. Automation in titration 73 Automated titration system for up to 28 samples (MATi 07) Fully automated system for the performance of potenti- ometric titrations such as acid/base, Redox and classic Automated halogenide titration in titr series ation of up to 28 sys- samples. The system is controlled with the tiamo™ titration software. tem At the for end of up the to 28 determination, the samples electrode and buret tips are cleaned automatically using the Pump Station and the beaker is emptied. Automated pipetting and titration system for up to 100 samples (MATi 08) Automated system for the performance of potentiome- tric titrations on acids and bases in up to 100 samples. Automated The sample is pipetted pipetting out of the beaker into and the external titration vessel, after which a completely automatic titration determination is system carried out. After for the titr up ation, to the exter- nal vessel is cleaned thoroughly using the membrane 100 pumps samples built into the Sample Processor. The control of this completely automatic analysis system takes place using the proven tiamo™ titration software. Automated COD determination (MATi 12) Automatic system for potentiometric titration of COD samples in series up to 21 samples. The titration is carried out directly in the reaction vessel on the rack. After-Automated wards, the electrode is COD cleaned determi automatically by - means of the membrane pump built into the sample changer nation and the reaction vessel is emptied. The control of this system is handled by the user-friendly tiamo™ titration software. Fully automated determination of the permanga- nate index, according to DIN EN ISO 8467 (MATi 13) Automated system for the determination of the perman- Fully ganate automated index in accordance with determi DIN EN ISO 8467. - Up to 24 samples can be placed on the rack and processed nation within one of series. the The permanga sample is pipetted from - the sam- ple beaker into the external titration cell and analyzed nate index, completely automatically accor in accor ding dance with to the require- DIN ments EN of the ISO DIN 8467 standard. The system is controlled by the tiamo™ titration software. 74 Automation in titration 862 Compact Titrosampler • Compact and inexpensive automated titration instru-time. „Plug & Play“ functionality of intelligent dosing ment unit, stirrer and USB printer, a high-precision measuring • Simple installation and operation input, operation per mouse click and a variety of dialog • Intelligent dosing unit and monitoring of the titrant options – this combination device leaves nothing to be • Ready for immediate use wished for. • Maximum precision thanks to high-resolution meas- uring input Maximum precision thanks to the new measuring • Live curve input • USB compact printer as option Just as is the case with the high-end titrator Titrando, the Compact Titrosampler is also equipped with a high-The 862 Compact Titrosampler is an instrument for the resolution measuring input which guarantees results with determination of dynamic (DET) and monotonic (MET) the greatest of precision. titrations with automatic equivalence point finding and endpoint titrations (SET) in a very small space. The com-USB interface bination of titrator and sample changer in a single instru-A multitude of instruments can be connected to the USB ment requires no more support surface than that of a interface of the Compact Titrosampler, even a number of commercially available analytical balance. Thanks to the them at once when a USB hub is used: USB printer, the results can be documented directly and • Keyboard or mouse clearly. • USB compact printer or commercially available USB A wide variety of analyses can be performed fully auto- DIN A4 printer matically in a total of 12 positions and the electrodes can • USB Memory Stick for methods and data backup be cleaned and/or conditioned between the determinations. The titration curve is directly in view thanks to the 862 Food/Beverage Compact Titrosampler large, clearly organized Live Display and the current The 862 Food/Beverage Compact Titrosampler is a com-status of the sample series is recognizable at once. pact and inexpensive instrument for the automatic per-Pressing samples can be given priority analysis at any formance of most potentiometric analyses required in the food industry. Equipped with extensive accessories, the 862 Food/Beverage Compact Titrosampler is ready for immediate use. 862 Salt Compact Titrosampler The 862 Salt Compact Titrosampler is comprised of a complete package for the analysis of chloride in a very wide variety of samples. The accessories included are tailored precisely to this application, thus enabling not only simple and rapid installation but also clearly organized documentation of the results with the USB printer that is included. Ordering Information 2.862.1010 862 Food/Beverage Compact Titrosampler 2.862.1110 862 Food/Beverage Compact Titrosampler with printer 2.862.2010 862 Salt Compact Titrosampler 2.862.2110 862 Salt Compact Titrosampler with 862 Food/Beverage Compact Titrosampler with accessories and printer printer Automation in titration 75 Robotic Analyzer packages Robotic Chloride Analyzer (2.855.1010) The complete package for the determination of chloride contains al the components for a ful y automatic chloride titration in the smallest possible space in a mini-Robotic mum of time. Chloride Instruments, Analyzer accessories, software and application know-how – simply everything is included. Robotic Acid-Base Analyzer (2.855.1020) The complete package for the determination of acids and/or bases contains all the components for a fully automatic acid-base titration in the smallest possible Robotic space in a Acid-Base minimum of time. Analy Instruments, - accessories, software and application know-how – simply everything zer is included. Robotic TAN/TBN Analyzer (2.855.2010) The complete package for the determination of TAN and/ or TBN contains all the components for a fully automatic TAN/TBN titration in the smallest possible space in a mini-Robotic mum of time. TAN/TBN Instruments, Analy accessories, softwar -e and application know-how – simply everything is included. zer Robotic Fluoride Analyzer (2.855.2020) The complete package for the determination of fluoride contains all the components for a fully automatic fluoride titration in the smallest possible space in a minimum of Robotic time. Fluoride Instruments, accessories, Analyzer software and application know-how – simply everything is included. 76 Automation in titration Robotic Transfer Analyzer (2.855.3020) The complete package for the determination of acid and base contents in very high numbers of samples contains all the components for a fully automatic acid/base Robotic titration in the Transfer smallest possible Analyzer space in a minimum of time. Instruments, accessories, software and application know-how – simply everything is included. Automation in titration 77 Sample preparation systems An overview of sample preparation with tip exchange unbeatable racks for flexibility any requirements pipetting freely programmable sequence high mechanical precision general max. 999 open vessel positioning transferring freely definable sealed vessel extended Liquid Handling sample volume max. 250 mL dosing dispensing diluting dissolving efficient spray nozzles simple dipping rod stirrer Robot-like carryover-free aspiration Rinsing sample stirring magnetic stirrer processing time proven diaphragm pumps externally solvent-resistant peristaltic pump heating cooling ICP Sample preparation degassing AAS high-frequency dilutions homogenizer IC homogenizing rod stirrer VA magnetic stirrer volumetric Karl Fischer titration filtering with filter exchange coulometric Applications potentiometric extracting titration parallel titrations direct measurement ion measurement standard addition 78 Automation in titration Robotic Soliprep The Metrohm automation program has long offered you cleaned in the external rinsing station. After the homoge-the opportunity of transferring your titration applications nization, an aliquot of the sample is aspirated and subse-to a completely automated system. The Robotic Soliprep quently filtered through a commercially available syringe is a new version of the proven 815 Robotic USB Sample filter (Luer connector). The Dosino used for the sample Processor that makes everyday routine work easier. The transport doses the sample at uniform speed onto the main area of utilization for the Robotic Soliprep systems filter, thus ensuring optimum filtration results. Needles is professional sample preparation. The Robotic Soliprep and filters are replaced for each sample and disposed of family is comprised of four packages that cover the dif-safely in the collection container after use. ferent standard sample preparation steps. All Soliprep systems offer the possibility of homogenizing solid sam-Up to 10 samples can be placed on the rack of the ples quickly and conveniently. Robotic Flexible Soliprep. Further steps proceed as already described for the Robotic Filtration Soliprep. The Up to 59 samples can be processed in a single run with filtrate can subsequently be pipetted, either directly or the Robotic Titration Soliprep. The sample needs only after additional dilution, in septum-sealed vials be weighed into the beaker and placed on the sample (11.6 mm). After completion of the series, the prepared rack. The reduction of the sample takes place subse-sam-ples can be easily removed from the sample rack in quently with the Polytron 1300 D. After homogenization, order to set the samples on the analyzer (e.g., IC or the sample is titrated at the other workstation. HPLC). Up to 24 samples can be placed on the rack of the Up to 24 samples can be placed on the Robotic Robotic Filtration Soliprep. The reduction of the sam-Flexible Soliprep for LC. After homogenization, an ple takes place with the Polytron 1300 D. During the aliquot of the sample is aspirated using a metal-free plas-following preparation steps, the Polytron aggregate is tic needle and subsequently transported through a commercially available syringe filter (Luer connector) and the Luer connector directly into the sample loop of the liquid chromatograph (LC). The control of this preparation system takes place com- pletely using the proven and flexible tiamo™ titration software or the MagIC Net chromatography software that can also document the individual preparation steps for each sample in a database. Ordering Information 2.815.1110 815 Robotic Titration Soliprep 2.815.2110 815 Robotic Flexible Soliprep 2.815.3110 815 Robotic Filtration Soliprep 2.815.4110 815 Robotic Soliprep for LC Options 6.9012.000 Dispersing aggregate for Polytron, 125 mm 6.9012.010 Dispersing aggregate for Polytron, 157 815 Robotic Filtration Soliprep mm Automation in titration 79 Automation peripheral devices Membrane pumps Liquids must frequently be pumped during titrations. The The 843 Pump Station (membrane) has two built-in aspiration of the titered-out sample solution is particularly membrane pumps. These can be controlled either via the convenient with automation. Following automatic run-interface either directly using remote signals or manually through of the preprogrammed rinsing and aspiration at the press of a button. cycles, the cleaned sample beakers and the electrodes that were used are available immediately for the next The two instruments are available in different versions determination. The waste is transferred to canisters stan-that differ primarily with respect to the accessories sup- ding by for convenient disposal. plied with them. The 823 Membrane Pump is a pump that can be used for many different applications. It was designed especially for operations and laboratory application and can be used for a broad spectrum of applications. It is suita- ble for pumping liquid media of any type and opens up a wide spectrum of applications with a flow rate of at least 450 mL/min. Ordering Information 2.823.0010 823 Membrane Pump Unit 2.823.0020 823 Membrane Pump Unit «aspirate» 2.823.0030 823 Membrane Pump Unit «rinse» 2.843.0020 843 Pump Station (membrane) 2.843.0030 843 Pump Station (membrane) - rinse/ aspirate for Compact Sample Changer 2.843.0050 843 Pump Station (membrane) - rinse/ 843 Pump Station Membrane aspirate for Sample Processors 80 Automation in titration Peristaltic pumps Liquids must frequently be pumped during titrations. The The 843 Pump Station (peristaltic) has two built-in aspiration of the titered-out sample solution is particularly peristaltic pumps. These can be controlled either via the convenient with automation. Following automatic run-interface either directly using remote signals or manually through of the preprogrammed rinsing and aspiration at the press of a button. The two instruments are availa-cycles, the cleaned sample beakers and the electrodes ble in various versions that differ primarily with respect to that were used are available immediately for the next the accessories supplied with them. determination. The waste is transferred to canisters stan- ding by for convenient disposal. A membrane pump can no longer be used with liquids that contain solids such as silver chloride precipitates. A peristaltic pump such as the 772 Pump Unit is to be preferred in such cases. Here, the user has the opportunity of using pump tubing made of a wide variety of materials and thus to adjust the resistance of the tubing to the medium to be pumped in optimal fashion. One tubing for aqueous applications and one for organic solvents are shipped as standard equipment along with the Pump Unit. Ordering Information 2.843.0120 843 Pump Station (peristaltic) 2.843.0130 843 Pump Station (peristaltic) - rinse/ aspirate for Compact Sample Changer 2.843.0150 843 Pump Station (peristaltic) - rinse/ aspirate for Sample Processors 2.772.0110 772 Pump Unit 2.772.0120 772 Pump Unit – aspirate 843 Pump Station Peristaltic 2.772.0130 772 Pump Unit – rinse Automation in titration 81 849 Level Control Additional equipment for Sample Processors for monitor- ing the filling level of rinsing or waste canisters via Remote. It prevents pumps from running dry and/or canisters from overflowing and is suitable for use with aqueous solutions, solvents and suspensions. The 849 Level Control can register both high liquid levels (e.g. warning that a waste container is about to overflow) and low liquid levels (e.g. storage container is about to run dry). Thanks to the conductivity measurement technique the level sensors can be used in different media. The sensor signal is registered by the Level Control and transmitted as a signal level to a remote connection of an automated system. This means that the 849 Level Control can be used in all Metrohm systems in which it is possible to scan remote lines. Ordering Information 2.849.0010 849 Level Control 2.849.0020 849 Level Control metal-free (for canisters) 849 Level Control with canister 2.849.0030 849 Level Control MF (for bottles) 82 Automation in titration 731 Relay Box • Two 115/230 V AC outputs The Relay Box provides four voltage outputs. Two • Two DC outputs 115/230 V AC outputs are used for switching the mains • One standard cable is sufficient for communication voltage. The maximum power delivery per output is with all Metrohm instruments 1‘150 W, so that the instrument can also be used for providing power to high-consumption devices such as Additional device for controlling up to four external heating baths or thermostats. devices such as pumps or valves with mains connection or direct current consumers via TTL signals, including In addition, the Relay Box has two DC outputs, whose connection cable for devices with a 25-pin «remote» voltages can be set to 5, 10, 18 or 24V. interface. Various Metrohm devices can be connected to the Relay Automated systems require the switching of heaters, Box via their remote interfaces. Regardless of the type of pumps, valves, thermostats or other external devices. device, a single standard cable is all that is required for This requires the use of relays to switch mains or low-communication. The Relay Box scans the 14 input lines voltage supplies on and off as necessary. The switching and switches the assigned voltage outputs accordingly. should take place via remote lines from a Titrino, Titrando, sample changer or other Metrohm instrument. The Relay Box meets all these requirements on a very small footprint. Ordering Information 731 Relay Box 2.731.0010 731 Relay Box Automation in titration 83 786 Swing Head Additional equipment for the Robotic Sample Processor XL for transferring / pipetting from smaller sample vessels into larger titration vessels on a rack or into an external titration cell that can be attached to the side of the work station. With a Swing Head, the number of samples and their sizes can be varied within a wide range. This increased flexibility results from the considerable extension of the range of positions that can be reached on the Sample Processor. The Swing Head works with highest accuracy: it moves pipette / transfer tips from one position to the next, millimetre by millimetre. Even sample transfer into an external titration cell is carried out fully automatically, thus greatly increasing the flexibility of the Sample Processor. While the transferred sample is analyzed in the cell, the next sample is already being prepared; this means an additional gain in time. In addition, the Swing Head can also be equipped with Robotic Arms that can take up and eject tools or serve as a holder for a homog- enizer for comminuting tablets. Ordering Information 2.786.0010 786 Swing Head with transfer head left 2.786.0020 786 Swing Head with transfer head right 2.786.0030 786 Swing Head with titration swing arm, left- or right-swinging 2.786.0040 786 Swing Head 2.786.0240 786 Swing Head, right-swinging, Reinforced 786 Swing Head reinforced 84 Automation in titration Stirrer 741 Magnetic Stirrer (2.741.0010) Magnetic stirrer for sample changers. The magnetic stirrer is located beneath the sample rack. 741 Magnetic Stirrer 802 Stirrer (2.802.0020) Rod stirrer for sample changer and Sample Processor. With 6.1909.020 Propeller stirrer 104 mm and fixed cable. 802 Stirrer Automation in titration 85 Polarography, voltammetry and CVS Polarography, voltammetry and CVS 87 88 Polarography, voltammetry and CVS Polarography, voltammetry and CVS Trace analysis with voltammetry 90 Determination of total metal and metal species 90 797 VA Computrace for trace analysis 91 797 VA Computrace with automatic standard addition for trace analysis 92 797 VA Computrace fully automated for trace analysis 93 Electrode kits for trace analysis 94 Sample preparation for trace analysis 95 909 UV Digester (230 V) 95 CVS – Cyclic Voltammetric Stripping 96 Introduction CVS 96 894 Professional CVS manual 97 894 Professional CVS semiautomated 98 894 Professional CVS fully automated for small sample series 99 894 Professional CVS fully and flexibly automated for large sample series 100 Electrode kits for CVS 101 Portable potentiostat 103 910 PSTAT mini 103 Polarography, voltammetry and CVS 89 Trace analysis with voltammetry Determination of total metal and metal species Voltammetry instruments from Metrohm are modest in Specific analysis of organics terms of servicing requirements, procurement price and It is not only metals that can be determined, but also dimensions, but nonetheless great in their detection various organic compounds. The technology is used in capabilities. organic chemistry, e.g. for the analysis of contaminations, or in pharmaceutical chemistry for the determina- Traces of toxic heavy metals can be analyzed in extremely tion of active ingredient concentrations. low concentrations without great effort. The detection limits are to be found without exception in the ppt Examples of interesting determinations: range, which means that the necessary sensitivity can be achieved in all cases. Voltammetry is one of the few • 4-carboxybenzaldehyde in terephthalic acid methods in existence for the speciation of analytes. • Free styrol in polystyrene • Vitamins in juices, vitamin preparations Metal analyses can be carried out with equivalent or better sensitivity, at a fraction of the procurement price Determination of anions of an AAS or ICP instrument. An additional plus for Some anions can also be determined with voltammetry. voltammetry are the low costs of ownership. Except for Of particular interest is the analysis of the species cya-small quantities of reagents, only tiny amounts of high- nide, sulfide, nitrite, nitrate and iodide.- purity nitrogen are required. No expensive flammable gases, no conversion of the laboratory with special gas supply and flue gas outlets, no expensive lamps and no time-consuming calibration of the analysis system. SbIII / SbV 200 ppt AsIII / AsV 100 ppt Applications that convince Bi 500 ppt Analysis of traces of metals Cd 50 ppt In addition to the determination of total concentrations, CrIII / CrVI 25 ppt as is usual with spectroscopic methods, with voltammetry Co 50 ppt it is also possible to specify between the different oxida-Cu 50 ppt tion stages of metal ions or the biological availability of FeII / FeIII 50 ppt heavy metals. A distinction can be made between free Pb 50 ppt and bound metal ions. This makes voltammetry an indis- Hg 100 ppt pensable element of environmental analysis. It is not Mo 50 ppt possible for spectroscopy to yield comparable statements Ni 50 ppt except after tedious separation of the metal species. Pt 0.1 ppt Thanks to its compact dimensions, the instrument can Rh 0.1 ppt also be used in mobile laboratories. SeIV / SeVI 300 ppt Tl 50 ppt Samples with high ion concentrations present no prob- W 200 ppt lem for voltammetry. Voltammetry is predestined for the U 25 ppt analysis of: Zn 50 ppt 1 ppt = part per trillion = 1 ng/kg • Water, waste water and sea water • Foods Typical detection limits in voltammetric trace analysis • Salts, pure chemicals • Galvanic baths 90 Polarography, voltammetry and CVS 797 VA Computrace for trace analysis The 10 most important benefits The 797 VA Computrace is a modern voltammetric • Voltammetric trace analysis and additive determination measuring stand that is connected to a PC via a USB port. in galvanics with a single instrument The computer software provided controls the measure- • Maximum sensitivity thanks to the combination of the ment, records the measured data and evaluates it. Oper-unique Multi-Mode Electrode pro with the installed ation is most straightforward due to the well-laid-out potentiostat structure of the program. The integrated potentiostat • Automation with the 863 Compact VA Autosampler or with galvanostat guarantees the highest sensitivity with the 838 Advanced VA Sample Processor reduced noise. • Archiving of the data in the Autodatabase program with report generator Voltammetry system for trace analysis and education. • More than 220 important analysis methods are in- Complete accessories with VA Computrace software and cluded in the scope of delivery all electrodes for a complete measurement system: Multi- • Output of the result in an unlimited number of formats Mode Electrode pro (MME pro), Ag/AgCl reference elec- • Unique EXPLORATORY mode, specially designed for trode and Pt auxiliary electrode. education at schools and universities • Metrohm monographs „Introduction to Polarography 797 VA Computrace – Manual or automated and Voltammetry“ and „Practical Voltammetry“ The 797 VA Computrace is a completely functional analy- • Built-in quality assurance with GLP mode, access rights sis system for meeting the highest expectations in terms for each user and automatic electrode test of accuracy and sensitivity. All solutions are added manu- • Simple operation using the clearly organized user interally. The various extension options, e.g., Dosinos or the face oriented to the Windows operating concept additions of auxiliary and standard solutions, sample • Connection to the USB port of the PC changer and automatic rinsing provide greater convenience. Ordering Information 797 VA Computrace 2.797.0010 797 VA Computrace for trace analysis Polarography, voltammetry and CVS 91 797 VA Computrace with automatic standard addition for trace analysis Easy to operate, partially automated analysis system for The sample is handled manually. The sample is added in voltammetric trace analysis and education, comprised of the measuring vessel by using a pipette and the analysis 797 VA Computrace with two 800 Dosinos for the auto-is started. This system is intended for users who value matic addition of auxiliary solutions. The computer soft-elegant and convenient operation at an attractive price ware provided controls the measurement, records the without having to use a sample changer. measured data and evaluates it. Operation is most straightforward due to the well-laid-out structure of the Complete accessories in the scope of delivery with VA program. The integrated potentiostat with galvanostat Computrace software and all electrodes for a complete guarantees the highest sensitivity with reduced noise. measurement system: Multi-Mode Electrode pro (MME pro), Ag/AgCl reference electrode and Pt auxiliary elec-Partially automated voltammetry system for inex- trode. pensive convenience Two auxiliary solutions can be added automatically to the measuring vessel. Calibration in voltammetry is accomplished by means of standard addition or calibration curve and is carried out automatically by one of the 800 Dosinos. The second 800 Dosino adds the electrolytes or buffer automatically. The Dosinos are completely con- trolled by the 797 VA Computrace. One additional 800 Dosino can be connected directly, as can four addi- tional ones by using an 846 Dosing Interface. A maximum of seven 800 Dosinos can thus be used. Ordering Information MVA-02 MVA-02 797 VA Computrace with automatic standard addition for trace analysis 92 Polarography, voltammetry and CVS 797 VA Computrace fully automated for trace analysis Fully automated analysis system for voltammetric trace enhances the accuracy of the determinations. In order to analysis and education, comprised of 797 VA Computrace increase the number of auxiliary solutions, one additional with 863 Compact VA Autosampler and two 800 800 Dosino can be connected directly, as can four addi-Dosinos for the automatic addition of auxiliary solutions. tional ones by using an 846 Dosing Interface. A maxi-The computer software provided controls the measure- mum of seven 800 Dosinos can thus be used. ment, records the measured data and evaluates it. Oper- ation is most straightforward due to the well-laid-out This system is the optimum solution for the automatic structure of the program. The integrated potentiostat analysis of small sample series that must be analyzed for with galvanostat guarantees the highest sensitivity with one or two analytes in a single analysis run. reduced noise. Complete accessories in the scope of delivery with VA Fully automated voltammetry system Computrace software and all electrodes for a complete Up to 18 samples can be investigated automatically, pre- measurement system: Multi-Mode Electrode pro (MME cisely and reproducibly. The software of the 797 VA pro), Ag/AgCl reference electrode and Pt auxiliary elec-Computrace controls the complete analysis sequence. trode. The samples are placed on the sample rack of the 863 Compact VA Autosampler, and the rest takes place auto- matically: the transfer of the samples into the measuring vessel with the built-in peristaltic pump, the voltammetric determination with the automatic addition of all of the auxiliary solutions by using two 800 Dosinos and the automatic rinsing with the 843 Pump Station. The reproducible and efficient rinse minimizes carry-overs and thus Ordering Information MVA-03 MVA-03 797 VA Computrace fully automated for trace analysis Polarography, voltammetry and CVS 93 Electrode kits for trace analysis MVA-Hg, equipment for mercury determination (6.5327.000) Complete set of accessories for the determination of mercury as per Application Bulletin 96. Contains rotat-M ing VA gold -Hg, working equipment electrode, reference electr for ode, glassy- carbon auxiliary electrode and other accessories. mercury determination scTRACE Gold equipment (6.5340.000) Complete accessories kit for the determination of arsenic with the scTRACE Gold as described in Application Bulletin 416. Contains electrode holder, scTRACE Gold (4 scTRA pieces), CE measuring Gold vessel, stirr equipment er and additional accesso- ries. 94 Polarography, voltammetry and CVS Sample preparation for trace analysis 909 UV Digester (230 V) • Control unit and wet end in a single housing Digestion is indispensable for the reliable determination • Digital input of digestion temperature and digestion of traces and ultratraces of metals in natural samples, as time organic sample components are generally disruptive to • Microprocessor-controlled regulation of digestion tem- analysis. The 909 UV Digester was designed for the perature and digestion time digestion of suspended particle-free water samples con- • Air cooling taining low to medium contents of organic material, e.g., • Digestion of up to 12 samples simultaneously natural surface waters. As a result of its low heavy metal • Short digestion times content, contaminations can very easily lead to dis- • Largely blank value-free, as only very small amounts of ruptions during determination. Liquid biological samples reagents are required such as urine or some foodstuffs such as fruit juices and • Also suitable for elements that form highly volatile alcoholic beverages can however also be digested with a compounds, e.g., mercury, arsenic and selenium modified procedure. A great advantage of the UV diges- tion is that only small amounts of digestion reagents Digestion instrument for UV photolysis of water samples need to be used and therefore the blank values can be with low to medium organic load. For sample preparation kept low. in trace element determination by means of voltammetry, ion chromatography and spectroscopy (AAS, ICP). Inte-12 samples can be radiated simultaneously in the 909 UV grated instrument with operating unit and wet end. With Digester. air cooling and automatic control of digestion tempera- ture and time. For 12 samples with a maximum of 12 mL sample volume each. Instrument for 220 - 240 V and 50 - 60 Hz. Ordering Information 909 UV Digester 2.909.0014 909 UV Digester (230 V) Polarography, voltammetry and CVS 95 CVS – Cyclic Voltammetric Stripping Introduction CVS Cyclic Voltammetric Stripping Analysis (CVS) and Cyclic Approximation Technique (LAT) or the Modified Linear Pulse Voltammetric Stripping Analysis (CPVS) are Approximation Technique (MLAT). Dilution Titration methods widely used in the electroplating industry for (DT) is used for the determination of the suppressors the determination of organic additives in electroplating while levelers are determined via Response Curve (RC). baths. A robust, inexpensive rotating disk electrode of simple construction made of platinum is installed in the The concentrations of the additives can be determined VA stand for these analyses in place of the Multi-Mode exactly with CVS or CPVS. The effective concentration of electrode that is otherwise used. This method is an indis-the respective additive in the bath sample is displayed pensable part of production control for many types of and printed out directly in mL of additive per L of bath. technical coatings and particularly in the manufacturing Topping-up to achieve nominal concentration thus can of printed circuit boards for electronic equipment. The be carried out very precisely as a result. This guarantees most important fields of application are acidic copper a continuous, malfunction-free production process. The baths and tin-lead baths. Quantitative determination of accuracy of the analysis results in particular have led to the additives takes place indirectly via their influence on the general acceptance of the method in the electro-the plating of the main component of the electroplating plating industry. bath. As the measurement utilizes a procedure that cor- responds to the production process, the activity of the Other methods, e.g., the classical Hull cell method, do additives and thus their effectiveness in the electroplating not allow the concentration to be determined, but only process is measured directly. provide an assessment of the quality of the deposited metal layer. The quantification of the various types of additives requires special calibration techniques, all of which are One of the pre-installed methods is loaded to perform available in Metrohm CVS systems. The so-cal ed the determination. The analysis can be started once a brighteners are determined with the aid of the Linear few parameters have been adjusted. Pre-finished methods that have been formulated in our Applications Laboratory for the most important bath types of leading manufacturers are supplied along with the instrument. 96 Polarography, voltammetry and CVS 894 Professional CVS manual The most important benefits The viva software is required for control, data recording • Compact instrument with small installation area and evaluation. • Measuring head that can be replaced with a single hand movement The 894 Professional CVS manual is supplied with exten- • Built-in certified calibrator for automatic instrument sive accessories and measuring head for rotating disk adjustment before each measurement electrodes. Electrode set and viva license are to be or- • Flexible Liquid Handling with 800 Dosinos dered separately. • Flexible automation options with 858 Professional Sample Processor, 919 IC Autosampler plus and 843 Manual system with versatile extension options Pump Station With the appropriate electrode set, the 894 Professional • Connection to the USB port of the PC CVS manual is a completely functional analysis system for meeting the highest expectations in terms of accuracy 894 Professional CVS manual is the introductory instru-and sensitivity. The measurement system offers maxi- ment for the high-end determinations of organic addi-mum flexibility through modular extension options and tives in electroplating baths with „Cyclic Voltammetric the practically unlimited configurability available with the Stripping“ (CVS). The proven Metrohm electrode tech-viva software. nique in combination with a completely newly designed potentiostat/galvanostat and the extremely high-perfor- viva mance viva software opens up new perspectives in CVS. The Professional CVS system is controlled with viva. The The replaceable measuring head enables rapid changes new software for CVS offers previously unachieved flexi-between various applications with different electrodes. bility with respect to method adjustment and automation The potentiostat with certified calibrator readjusts itself and thus sets new standards in the determination of automatically before each measurement and guarantees organic additives with CVS. viva is available in a single-a maximum in precision. user version or as a network option for one client-server installation. Ordering Information 894 Professional CVS manual 2.894.0210 894 Professional CVS manual Polarography, voltammetry and CVS 97 894 Professional CVS semiautomated The most important benefits between various applications with different electrodes. • Compact instrument with small installation area The potentiostat with certified calibrator readjusts itself • Two 800 Dosinos for the automatic addition of auxil- automatically before each measurement and guarantees iary solutions a maximum in precision. • Liquid Handling can be extended without limit with additional 800 Dosinos Two 800 Dosinos (supplied) permit the automatic addi- • Measuring head that can be replaced with a single tion of auxiliary solutions during the determination, e.g., hand movement VMS, standard solutions or samples for the Dilution Titra- • Built-in certified calibrator for automatic instrument tion technique (DT). adjustment before each measurement • Flexible automation options with 858 Professional The viva software is required for control, data recording Sample Processor, 919 IC Autosampler plus and 843 and evaluation. Pump Station • Connection to the USB port of the PC The 894 Professional CVS semiautomated is supplied with extensive accessories and measuring head for rotat- 894 Professional CVS semiautomated is a convenient ing disk electrodes. Electrode set and viva license are to high-end routine analyzer for determinations of organic be ordered separately. additives in electroplating baths with „Cyclic Voltammetric Stripping“ (CVS). The proven Metrohm electrode tech-Convenient routine measurements nique in combination with a completely newly designed With the appropriate electrode set, the 894 Professional potentiostat/galvanostat and the extremely high-perfor-CVS semiautomated enables the determination of sup- mance viva software opens up new perspectives in CVS. pressors with Dilution Titration (DT). All solutions are The replaceable measuring head enables rapid changes added automatically during the determination by the two supplied 800 Dosinos, e.g., VMS, standard solutions or samples for the Dilution Titration technique (DT). The determination proceeds automatically, from the prepara- tion of the sample to the calculation of the final result. The performance capability can be further increased through modular extension options and the practically unlimited configurability available with the viva software. viva The Professional CVS system is controlled with viva. The new software for CVS offers previously unachieved flexibility with respect to method adjustment and automation and thus sets new standards in the determination of organic additives with CVS. viva is available in a single-user version or as a network option for one client-server installation. Ordering Information 894 Professional CVS semiautomated with 800 Dosino 2.894.1210 894 Professional CVS semiautomated 98 Polarography, voltammetry and CVS 894 Professional CVS fully automated for small sample series Automated analysis system for the determination of of accuracy. And different methods can be combined in organic additives in electroplating baths using the CVS a single measurement sequence. technique („Cyclic Voltammetric Stripping“). Comprised of 894 Professional CVS, 919 IC Autosampler plus, four The system is based on the 894 Professional CVS with 800 Dosinos, 843 Pump Station, measuring head for four 800 Dosinos for the automatic addition of auxiliary rotating disk electrodes and extensive accessories. For solutions. VMS and the electroplating bath sample are small sample series of up to 14 samples. added by using 800 Dosinos in cases of suppressor deter- mination. For the determination of brighteners, the The viva software is required for control, data recording intercept solution and brightener standard solution are and evaluation. PC, electrode set and viva license are to added by 800 Dosino dosing systems; the peristaltic be ordered separately. pump of the 919 IC Autosampler plus is used for trans- ferring the sample automatically from the sample vessel Fully automated analysis system for the determi- on the sample rack into the measuring vessel on the 894 nation of organic additives with CVS in routine Professional CVS. The attached 843 Pump Station emp-laboratory work ties and rinses the measuring vessel automatically after MVA-20 is the version in our top system for fully auto-each sample. mated additive determination in electroplating baths with CVS (Cyclic Voltammetric Stripping) for small sample viva series. Up to 27 samples can be investigated with respect The Professional CVS system is controlled with viva. The to suppressor content with the 919 IC Autosampler plus. new software for CVS offers previously unachieved flexi-Up to 14 samples can be analyzed automatically during bility with respect to method adjustment and automation brightener determination. The possibility of recalibrating and thus sets new standards in the determination of methods during a sample series guarantees the highest organic additives with CVS. viva is available in a single-user version or as a network option for one client-server installation. Ordering Information MVA-20 MVA-20 894 Professional CVS fully automated for small sample series Polarography, voltammetry and CVS 99 894 Professional CVS fully and flexibly automated for large sample series Automated analysis system for high-performance, flexible of recalibrating methods during a sample series guaran-determination of organic additives in electroplating baths tees the highest of accuracy. And different methods can using the CVS technique („Cyclic Voltammetric Strip-be combined in a single measurement sequence. ping“). Comprised of 894 Professional CVS, 858 Professional Sample Processor, four 800 Dosinos, 843 The system is based on the 894 Professional CVS with Pump Station, measuring head for rotating disk elec-four 800 Dosinos for the automatic addition of auxiliary trodes and extensive accessories. For sample series of up solutions. VMS and the electroplating bath sample are to 56 samples. added by using 800 Dosinos in cases of suppressor deter- mination. For the determination of brighteners, the The viva software is required for control, data recording intercept solution and brightener standard solution are and evaluation. PC, electrode set and viva license are to added by 800 Dosino dosing systems; the peristaltic be ordered separately. pump of the 858 Professional Sample Processor is used for transferring the sample automatically from the sam- Fully automated analysis system for the determi- ple vessel on the sample rack into the measuring vessel nation of organic additives with CVS in routine on the 894 Professional CVS. The attached 843 Pump laboratory work Station empties and rinses the measuring vessel auto-MVA-21 is the version in our top system for fully auto- matically after each sample. mated additive determination in electroplating baths with CVS (Cyclic Voltammetric Stripping) for large sample viva series. Up to 56 samples can be investigated with respect The Professional CVS system is controlled with viva. The to suppressor content with the 858 Professional Sample new software for CVS offers previously unachieved flexi-Processor. Up to 28 samples can also be analyzed auto- bility with respect to method adjustment and automation matically during brightener determination. The possibility and thus sets new standards in the determination of organic additives with CVS. viva is available in a single-user version or as a network option for one client-server installation. Ordering Information MVA-21 MVA-21 894 Professional CVS fully and flexibly automated for large sample series 100 Polarography, voltammetry and CVS Electrode kits for CVS CVS electrode equipment with 1 mm platinum electrode for Professional CVS instruments (6.5339.000) Complete electrode set for the determination of organic CVS additives electr in electr ode oplating equipment baths with CVS (Cyclic Voltam- metric Stripping). Contains rotating platinum working with electrode 1 mm (electrode platinum diameter: 1 mm), r elec eference - elec- trode, platinum auxiliary electrode and electrolyte solu-trode tions. for Professional CVS instruments CVS electrode equipment with 2 mm platinum electrode for Professional CVS instruments (6.5339.010) Complete electrode set for the determination of organic CVS additives electr in electr ode oplating equipment baths with CVS (Cyclic Voltam- metric Stripping). Contains rotating platinum working with electrode 2 mm (electrode platinum diameter: 2 mm), r elec eference - elec- trode, platinum auxiliary electrode and electrolyte solu-trode tions. for Professional CVS instruments CVS electrode equipment with 3 mm platinum electrode for Professional CVS instruments (6.5339.020) Complete electrode set for the determination of organic CVS additives electr in electr ode oplating equipment baths with CVS (Cyclic Voltam- metric Stripping). Contains rotating platinum working with electrode 3 mm (electrode platinum diameter: 3 mm), r elec eference - elec- trode, platinum auxiliary electrode and electrolyte solu-trode tions. for Professional CVS instruments Polarography, voltammetry and CVS 101 viva – Software for CVS Modern, user-friendly software for the performance of for example, standard addition volumes can be calculated CVS determinations. Thanks to its easy operation and autonomously. maximum flexibility, viva enables individual and problem-oriented method programming for CVS measuring tech- All determinations are stored in a database for conven- nology for the first time. ient data management where they can be viewed along with all of the determination, method and instrument The „Workplace“ program part is the cockpit of viva. parameters. Here all of the information necessary for the determina- tion is visible at a glance. It goes without saying that the The most important features at a glance: „Workplace“ can be individually configured so that only • Freely configurable determination overview the data relevant to the user is displayed. The method • High-performance sort, search and filter functions that used and the associated evaluation parameters are logi-are simple to operate cally structured and clearly displayed in the method • Recalculation and recalibration functions window. The measured voltammograms and the associ- • Report generator for customized structuring of the ated calibration curve are displayed in the curve window. analysis report • Client-server version for the central storage of all viva is the first and only software for CVS that enables methods and determinations on a single server. All individual, problem-oriented method programming with measured data is thus available throughout the com- the aid of a graphical method editor. Numerous tempany plates simplify method development. The intelligence • Freely definable access permissions for each user functions of viva make it possible to have the run of the method be made dependent on results of the current viva is available in the viva Full single-user version with measurement that have already been calculated. Thus, 1 license for one computer. The alternative is the viva Multi client-server version with 3 licenses for three computers for company networks, which makes it possible to store all of the data on a central server. Separate licenses can be obtained for additional computers. Ordering Information 6.6065.102 viva 1.0 Full CD: 1 license viva workplace 6.6065.103 viva 1.0 Multi CD: 3 licenses 102 Polarography, voltammetry and CVS Portable potentiostat 910 PSTAT mini • Small and compact The most important applications • Mobile • Training in electrochemistry (student internships, • Inexpensive demonstration experiments) • All of the important electrochemical measurement • Electrochemical research and development (sensor techniques development, reversibility of electrochemical reactions, • Maintenance-free disposable sensors reaction kinetics) • Power supply via USB • Simple, intuitive PSTAT software PSTAT software • Monograph „Electrochemistry – A workbook for 910 As a result of its intuitive operability, PSTAT software is PSTAT mini“ particularly suitable for training in electrochemistry. Measurement is of the essence. That is why the software The ideal introductory instrument for electro- includes only those functions that are really important for chemistry measurement, i.e. measuring parameters, curves and 910 PSTAT mini is a small and compact, PC-controlled manual signal evaluation. All of the fundamental electro-potentiostat with USB connector for training purposes as chemical measurement techniques are available: Cyclic well as simple applications in research and development. Voltammetry (CV) for investigating the mechanism and The PSTAT software provided is easy and intuitive to op-kinetics of electrode reactions or for characterizing modi-erate and covers the most important electrochemical fied sensors; Differential Pulse Voltammetry (DP) and measuring techniques. Included in the scope of delivery Square Wave Voltammetry (SWV) for quantitative deter-are inexpensive disposable thick film sensors that can be mination of electrochemically active substances such as utilized directly, without preparation and conditioning. mercury, organic substances or cadmium and lead after modification. Chronoamperometric Detection (AD) for The 910 PSTAT mini is supplied with extensive accessories demonstrating the functional principle of an amperometric in a transport case. biosensor such as a glucose sensor. Screen-printed electrodes (SPE) Inexpensive disposable thick film electrodes make electrochemistry easy. The electrode is inserted into the hold-er and measurement can begin without further prepara- tion. Each sensor contains the 3 required electrodes: the working electrode, made of carbon, gold or platinum, a silver reference electrode and a carbon auxiliary electrode on a ceramic holder. Monograph „Electrochemistry – A workbook for 910 PSTAT mini“ The monograph provides an easy introduction to the field of electrochemistry. The book in its handy format includes experiments that describe fundamental phe-nomena of electrochemical analytics. These experiments can be readily carried out with the 910 PSTAT mini and the electrodes supplied. Ordering Information 910 PSTAT mini 2.910.0010 910 PSTAT mini Polarography, voltammetry and CVS 103 Stability measuring instruments Stability measuring instruments 105 106 Stability measuring instruments Stability measuring instruments Oxidation stability of fats and oils 108 892 Professional Rancimat 108 Oxidation stability of biodiesel and biodiesel blends 109 893 Professional Biodiesel Rancimat 109 Thermostability of PVC 110 895 Professional PVC Thermomat 110 Software for stability measuring instruments 111 StabNet 111 Stability measuring instruments 107 Oxidation stability of fats and oils 892 Professional Rancimat • Control of all the instrument functions from the com- Oxidation stability of fats and oils in the food puter industry • Individual start of each measuring position directly on The Rancimat method is used as a default parameter in the instrument the food industry for quality control during the manufac- • Overview of the status of all measuring positions on ture of fats and oils, or for incoming goods checks in the instrument display processing industries. In addition to vegetable oils and • Highest reliability and simple operation through unique fats, it is also possible to check animal fats such as lard, accessories tallow or fish oil. It is also possible, with the help of the • Inexpensive disposable glass components 892 Professional Rancimat, to characterize the effective- • Robust conductivity measuring cell with electrical con- ness of antioxidants that are added to foods in order to nections integrated in the lid slow down oxidative decomposition. • 2 heating blocks with 8 measuring positions per instru- ment. Up to 4 instruments can be connected to a PC Standards • Expanded gas flow range: 1 - 25 L/h • AOCS Cd 12b-92 (AOCS - American Oil Chemists‘ Soci- • USB connector ety): Sampling and analysis of commercial fats and oils: • Compact dimensions and low weight Oil Stability Index • ISO 6886: Animal and vegetable fats and oils - Deter- Analysis system for the simple and safe determination of mination of oxidative stability (accelerated oxidation the oxidation stability of natural fats and oils with the test) well-established Rancimat method. All accessories neces- • 2.4.28.2-93: Fat stability test on Autoxidation. CDM, sary for carrying out determinations are included in the Japan scope of delivery. The StabNet software is required for instrument control, data recording and evaluation and Oxidation stability of fat-containing foods for data storage. The 892 Professional Rancimat can also be used for the determination of the oxidation stability of fat-containing foods. Examples: • Instant noodle dishes • Nuts, almonds • Cookies, biscuits • Potato chips and similar snacks Oxidation stability of cosmetics In addition to foods, the oxidation stability of aliphatic cosmetics or of cosmetics additives can also be determined with the help of the 892 Professional Rancimat. Ordering Information 892 Professional Rancimat 2.892.0010 892 Professional Rancimat 108 Stability measuring instruments Oxidation stability of biodiesel and biodiesel blends 893 Professional Biodiesel Rancimat • Control of all the instrument functions from the com- Oxidation stability of biodiesel (fatty acid methyl puter esters, FAME), biodiesel blends and diesel • Individual start of each measuring position directly on Biodiesel has relatively little storage stability, as it (like the instrument natural fats and oils) is slowly oxidized by atmospheric • Overview of the status of all measuring positions on oxygen. The substances that arise thereby could lead to the instrument display damage in the motor. It is for this reason that oxidation • Highest reliability and simple operation through unique stability is an important default parameter in a series of accessories standards that define the minimum quality standards of • Inexpensive disposable glass components biodiesel. This determination can be carried out simply • Robust conductivity measuring cell with electrical con- and reliably with the 893 Professional Biodiesel Rancimat. nections integrated in the lid • 2 heating blocks with 8 measuring positions per instru- Standards ment. Up to 4 instruments can be connected to a Testing requirements computer • ASTM D 6751 (ASTM - American Society for Testing • Expanded gas flow range: 1 - 25 L/h and Materials) „Standard specification for biodiesel • USB connector fuel blend stock (B100) for middle distillate fuels“ • Compact dimensions and low weight • ASTM D 7467 „Standard Specification for Diesel Fuel Oil, Biodiesel Blend (B6 to B20)“ Analysis system for simple and safe determination of the • EN 14214 „Liquid petroleum products - Fatty acid oxidation stability of biodiesel (fatty acid methyl esters, methyl esters (FAME) for use in diesel engines and FAME) and biodiesel blends in accordance with the stan-heating applications - Requirements and test methods“ dards EN 14112, EN 15751 and EN 16568. All accesso- • EN 590 „Automotive fuels - Diesel - Requirements and ries necessary for carrying out determinations are includ- test methods“ ed in the scope of delivery. The StabNet software is required for instrument control, data recording and Test methods evaluation and for data storage. • EN 14112 „Fat and oil derivatives - Fatty acid methyl esters (FAME) - Determination of oxidation stability (accelerated oxidation test)“ • EN 15751 „Automotive fuels - Fatty acid methyl esters (FAME) fuel and blends with diesel fuel - Determination of oxidation stability by accelerated oxidation method“ • EN 16568 „Automotive fuels - Fatty acid methyl esters (FAME) fuel and blends with diesel fuel - Determination of oxidation stability by rapidly accelerated oxidation method at 120 °C“ Ordering Information 893 Professional Biodiesel Rancimat 2.893.0010 893 Professional Biodiesel Rancimat Stability measuring instruments 109 Thermostability of PVC 895 Professional PVC Thermomat • Control of all the instrument functions from the com- Thermostability of PVC puter Chlorinated plastics based on poly(vinyl chloride) (PVC) • Individual start of each measuring position directly on decompose at higher temperatures with accompanying the instrument release of gaseous HCl. The thermostability of the PVC • Overview of the status of all measuring positions on material is defined as the time until HCl is released and is the instrument display determined by the measurement of a defined conductivity • Highest reliability and simple operation through unique change in the measuring cell. accessories • Inexpensive disposable glass components Standards • Robust conductivity measuring cell with electrical con- • DIN 53381-1 „Testing of plastics; determination of nections integrated in the lid thermostability of polyvinyl chloride (PVC); dehydro- • 2 heating blocks with 8 measuring positions per instru- chlorination methods“ ment. Up to 4 instruments can be connected to a • ISO 182-3 „Plastics - Determination of the tendency of computer compounds and products based on vinyl chloride • Expanded gas flow range: 1 - 25 L/h homopolymers and copolymers to evolve hydrogen • USB connector chloride and any other acidic products at elevated • Compact dimensions and low weight temperatures - Part 3: Conductometric method“ Analysis system for the automatic determination of the thermostability of poly(vinyl chloride) (PVC) and related copolymers. All accessories necessary for carrying out determinations are included in the scope of delivery. The StabNet software is required for instrument control, data recording and evaluation and for data storage. Ordering Information 895 Professional PVC Thermomat 2.895.0010 895 Professional PVC Thermomat 110 Stability measuring instruments Software for stability measuring instruments StabNet Modern, user-friendly software for control and data • High data security due to manipulation-proof database handling of stability measuring instruments. The soft-and automatic backup functions ware permits checks, data acquisition, evaluation and • User administration with freely configurable access monitoring, as well as report generation of stability rights measurements. • In compliance with all GLP and FDA requirements Graphical user interface for routine operations, extensive StabNet is available in the StabNet Full single-user version database programs, method development, system con-with 1 license for a max. of 4 stability measuring instru- figuration, very flexible user administration, extensive ments on one computer. The alternative is the StabNet data export functions, individually configurable report Multi client-server version with 3 licenses for three com-generator. StabNet fulfills the directives pursuant to FDA puters for company networks, which makes it possible to 21 CFR Part 11. store all of the data on a central server. Separate licenses can be obtained for additional computers. All determinations are stored in a database for conven- ient data management where they can be viewed along with all of the determination, method and instrument parameters. The most important features at a glance: • Clear and structurally well-organized user interface • Database with flexible functions for filtering, sorting and statistics • High transparency of results by storage of all determi- nation, method and instrument parameter data and the history when measured data is reevaluated or recalculated Ordering Information 6.6068.102 StabNet 1.0 Full CD: 1 license StabNet workplace 6.6068.103 StabNet 1.0 Multi CD: 3 licenses Stability measuring instruments 111 Near-infrared spectroscopy Near-infrared spectroscopy 113 114 Near-infrared spectroscopy Near-infrared spectroscopy Introduction to near-infrared spectroscopy 116 Overview of NIRS instruments 116 Metrohm NIRSystems 117 Laboratory and atline for solid samples 118 Introduction 118 NIRS DS2500 Analyzer 119 NIRS XDS – the all-rounder 120 Laboratory and atline for liquid samples 121 Introduction 121 NIRS XDS RapidLiquid Analyzer 122 Fiber Optics – the flexible ones 123 Process analyzers 124 Introduction 124 NIRS XDS Process Analyzers – SingleFiber 125 NIRS XDS Process Analyzers – MicroBundle 126 NIRS XDS Process Analyzer – DirectLight/ NonContact 127 NIRS Analyzer PRO 128 Near-infrared spectroscopy 115 Introduction to near-infrared spectroscopy Overview of NIRS instruments Near-infrared spectroscopy (NIRS) is a versatile analysis procedure that has been applied successfully in the pharmaceutical and chemical industries for more than 25 years. This simple, rapid (< 30 s measuring time) and nondestructive physical measurement method offers, for practically every sample matrix, an accurate and precise analysis of chemical and physical parameters comparable to reference methods. As an additional major benefit, near-infrared (NIR) analyses require no sample preparation or the use of hazardous chemicals, solvents or reagents. The Metrohm NIR product range comprises not only the simple and intuitive NIR laboratory analyzers, but also robust, user-friendly NIR process analyzers. n Dedicated systems n Temperature controller up to 65 °C n Optional temperature controller up to 200 °C p Different fiber optic probes are available p With transflectance options Laboratory analyzer, atline analyzer XDS Rapid XDS Interactance XDS Transmission Sample type XDS Rapid XDS MultiVial XDS MasterLab XDS RapidLiquid XDS SmartProbe Content Solid OptiProbe OptiProbe DS2500 Analyzer ContentAnalyzer Analyzer Analyzer Analyzer Analyzer Analyzer Analyzer Analyzer Powders n n n n n n n Coarse solids/ n n n n n n granulates Solids/film/paper n n n n n Tablets/capsules n n n n in reflection Tablets/capsules n in transmission Opaque liquids n n p p n n n Pastes/creams p p p p n n p Viscous liquids/gels p p p p n n n n Clear liquids p p p p n p p n p 116 Near-infrared spectroscopy Metrohm NIRSystems Metrohm offers NIR applications for all process environ- and sensitivity, the duration of the process run and the ments. Metrohm NIRSystems instruments can be in- monitoring and control requirements. Below is a short stalled in the laboratory, atline or directly into a process overview of Metrohm NIRSystems instruments. A suitable stream, dryer, extruder, or reactor. The measurement analyzer is available for every sample type and processing mode and location of the analyzer depend on the optical environment. properties of the samples, the required analyte selectivity Metrohm NIRSystems Family Lab/atline Process NIRS XDS NIRS DS2500 NIRS XDS Process Analyzer Analyzer NIRS Analyzer PRO Analyzer N D X S R I S N D X S R I S D X S R I N S NIRS XDS RapidContent N S D X S R I I N X S R S D NIRS Analyzer PRO – Process Analyzer – Process Analyzer – Process Analyzer – Analyzer SmartProbe Analyzer RapidLiquid Analyzer DirectLight/NonContact Microbundle SingleFiber SinglePoint SinglePoint DirectLight/NonContact N D X S R I S N S D X S R I N D X S R I S NIRS XDS RapidContent Process Analyzer – Interactance NIRS Analyzer PRO – Process Analyzer – Analyzer – Solids ContactReflection Microbundle 4 OptiProbe Analyzer SingleFiber 4 Channels Channels N D X S R I S N S D X S R I N D X S R I S D X S R I N S Process Analyzer – Transmission NIRS Analyzer PRO – Process Analyzer – MultiVial Analyzer FiberSystem Microbundle 9 OptiProbe Analyzer SingleFiber 9 Channels Channels D X S R I N S MasterLab Analyzer Process analyzer XDS Process Analyzer NIRS Analyzer PRO Sample type SingleFiber MicroBundle DirectLight ContactReflection Fiber DirectLight Powders p n n p n Coarse solids/ p n n p n granulates Solids/film/paper p n n p n Tablets/capsules in reflection Tablets/capsules in transmission Opaque liquids p p p Pastes/creams p p n p Viscous liquids/gels p p p Clear liquids p p p Near-infrared spectroscopy 117 Laboratory and atline for solid samples Introduction Metrohm NIRSystems laboratory analyzers with their The NIRS XDS RapidContent Analyzer performs reflec-patented monochromator can be operated in all labora- tance analysis on materials in bags, vials, or sample tories: from quality control through research and devel-beakers and transflectance analysis of liquids in beakers. opment to plant laboratories. Modular sampling accesso- The NIRS XDS RapidContent Analyzer with Solids Module ries allow for analyses of powders, granules, solids, slur-provides large area sampling for nonhomogeneous pow- ries, gels, pastes, and turbid or clear liquids. Since NIR ders, fibrous materials, flakes, and pellets. analyses are performed on unmodified samples, present- ing the samples to the instrument is the most important aspect of NIR analysis. The modular design of Metrohm NIRSystems laboratory analyzers ensures that analyses are optimized for specific sample types. The NIRS DS2500 Analyzer enables simple routine ana- lyses in difficult environments and meets the standards of protection class IP65. True transmission and reflection measurements for solid dosage forms are carried out with the NIRS XDS MasterLab Analyzer. 118 Near-infrared spectroscopy NIRS DS2500 Analyzer • Compact analyzer for reflectance measurements from very simple to sophisticated. With this high-perfor- • Maximum optical performance across the entire wave- mance instrument, you and your team can be sure that length range (400 to 2,500 nm) you are getting the highest level of quality control at all • Consistent results, even in harsh environments stages of production. • Network-capable via LAN (local) or direct PC connection • New predispersive monochromator Specially developed for this purpose • Several optional sampling accessories The NIRS DS2500 Analyzer was created as a high-perfor- mance instrument for harsh production environments. Near-infrared analyses are becoming ever better. With Robust, easy-to-use and IP65 certified, it withstands the compact NIRS DS2500 Analyzer, near-infrared analy-humidity, dust, vibrations and temperature fluctuations. sis has taken yet another step into the future of routine This solidity of its construction makes the NIRS DS2500 analysis. This dedicated analyzer offers exceptional accu- Analyzer suitable for atline use by anyone in any produc- racy across a broad wavelength range of 400 to tion plant. The NIRS DS2500 complies with pharma 2,500 nm and is designed for use in the receiving area or regulations and supports the workflows of the nutraceu-atline in the nutraceutical industry. tical industry. Unmatched optical performance The predispersive monochromator technology now being utilized in the NIRS DS2500 guarantees a high degree of versatility and stability across the entire spectral range from 400 to 2,500 nm. The NIRS DS2500 uses signal-noise ratio to perform, in less than one minute, high-precision analyses of parameters ranging Ordering Information NIRS DS2500 Analyzer 2.922.0010 NIRS DS2500 Analyzer Near-infrared spectroscopy 119 NIRS XDS – the all-rounder The NIRS XDS family guarantees more rapid analyses and NIRS XDS RapidContent Analyzer/Solids even more accurate results for quality control in the labo-Composition or material identification testing is ratory. With the NIRS XDS Analyzers, you can replace performed either in the laboratory or atline, on samples routine tests, reduce product hold time and virtually elim-contained in their original vials, bags or bottles. The inate quarantine time. Solids Module extends analysis to virtually any solid form from fine powders to coarse granular materials, pellets, The NIRS XDS Analyzer is part of a generation of dedi- and flakes. An optional variable spot-size feature enables cated NIR analysis instruments for rapid nondestructive the sample illumination to be adjusted based on the measurements of solid chemical and pharmaceutical physical properties of your samples. samples in addition to liquid samples. Special modules support optimum analysis performance. The presence of NIRS XDS MultiVial Analyzer modules that can be exchanged during operation pro-The NIRS XDS MultiVial Analyzer supports acquisition of vides great flexibility. spectra in an unattended mode, freeing the operator to prepare other samples, analyze data, etc. The versatile Identification, qualitative and quantitative methods are sampling mechanism of the NIRS XDS MultiVial Analyzer easily created with the advanced, user-friendly, network-offers a movable (X-Y) sampling platform, suitable for compatible Vision® software. Precise and accurate analy-handling a tray of multiple vials. An integrated variable sis is accomplished with the press of a key or click of the spot-size feature enables the sample illumination to be mouse. adjusted based on the diameter of the vials being used. Advantages NIRS XDS MasterLab Analyzer • Ease-of-use The NIRS XDS MasterLab Analyzer offers pharmaceutical • Robust and accurate manufacturers a rapid, reliable test method covering the • Flexible full array of solid dosage forms: layered, coated or cored • Effortless method transferability tablets, capsules, caplets, gel tabs and gel caps. The versatile sampling mechanism of the NIRS XDS MasterLab Analyzer offers an automated and unattended reflectance or transmission analysis of tablets or vials. The optional sample cell for coarse granular substances extends analysis to nonhomogeneous solid forms rang- ing from fine powders to coarse granular materials, pel- lets and flakes by averaging over a large area. Ordering Information 2.921.1110 NIRS XDS RapidContent Analyzer 2.921.1120 NIRS XDS RapidContent Analyzer – Solids 2.921.1210 NIRS XDS MultiVial Analyzer NIRS XDS RapidContent Analyzer 2.921.1310 NIRS XDS MasterLab Analyzer 120 Near-infrared spectroscopy Laboratory and atline for liquid samples Introduction Metrohm NIRSystems offers dedicated NIR analyzers for the analysis of clear or viscous liquids that can be easily used in the quality control laboratory or at the production site. Temperature monitoring during measurement is very important with temperature-dependent aqueous and liquid samples. Because many oil-based samples are in solid form at room temperature, a heater and a tem- perature controller are required for increasing sample transparency for NIR spectral consistency. It is for this reason that a temperature control feature is integrated into the Metrohm NIRS XDS RapidLiquid Analyzer for higher performance and accurate measurement. The NIRS XDS RapidLiquid Analyzer performs liquid anal- ysis in controlled temperature environments at room temperature and up to 65 °C. The optional Vial Heater Module, with which the temperature can be heated up and controlled up to as high as 200 °C, is available for the NIRS XDS Transmission OptiProbe Analyzer. Near-infrared spectroscopy 121 NIRS XDS RapidLiquid Analyzer • NIR XDS technology guarantees simple utilization and The NIRS XDS RapidLiquid Analyzer is designed to pro-effortless method transferability vide rapid quantitative and qualitative results for quality • Uses standard quartz cuvettes and disposable vials control and assurance. With this Analyzer, virtually any • Temperature controlled analysis of virtually all liquids or liquid or suspension can be analyzed in both laboratory suspensions and atline situations. Samples are effortlessly analyzed in • No sample preparation, no reagents, no waste quartz cuvettes or disposable vials for trouble-free clean • Network-capable analyzer for centralized database up. A temperature-controlled sample compartment pro-management vides the stable sample environment essential for precise • Hot-swappable modules that can be replaced in just a measurements. few minutes without performance loss. Only the XDS platform offers maximum system perfor- The NIRS XDS RapidLiquid Analyzer, based on XDS near- mance and instrument matching for decreased method infrared technology, provides the next generation of development time, and effortless method transfer. Iden-dedicated NIR systems for the rapid and nondestructive tification, qualitative and quantitative methods are easily analysis of liquid chemical and pharmaceutical formu-implemented with the user-friendly, network-capable lations. The NIRS XDS RapidLiquid Analyzer is designed to Vision® software. Precise and accurate analysis is accom-provide rapid quantitative and qualitative results for qual-plished with the press of a key or click of the mouse. ity control and assurance. Ordering Information NIRS XDS RapidLiquid Analyzer 2.921.1410 NIRS XDS RapidLiquid Analyzer 122 Near-infrared spectroscopy Fiber Optics – the flexible ones The NIRS XDS Fiber Optics Analyzer family offers fiber NIRS XDS Interactance OptiProbe Analyzer optics modules for a wide variety of customer applica-With the NIRS XDS Interactance OptiProbe Analyzer, you tions. The NIRS XDS SmartProbe Analyzer enables receive both reflectance and immersion probes for a analyses of solids and liquids to be performed directly in wide variety of sample types. The reflectance probe is shipping containers. Fiber optic probes attached to the used for scanning solids, highly scattering liquids and NIRS XDS Interactance OptiProbe or to the NIRS XDS slurries. The immersion probe analyzes aqueous prod-Transmission OptiProbe Analyzer also permit the use of ucts, clear liquids and solvents. The fiber optics design of laboratory instruments for scale-up and reaction moni-the NIRS XDS Interactance OptiProbe Analyzer allows it toring. Solid or liquid samples can be analyzed using to be directly interfaced in difficult and hazardous sam-different probe types. pling environments. NIRS XDS SmartProbe Analyzer NIRS XDS Transmission OptiProbe Analyzer With the NIRS XDS SmartProbe Analyzer, you can replace With the NIRS XDS Transmission OptiProbe Analyzer, you routine tests, expedite the production process and virtu-can replace routine tests, expedite the production ally eliminate quarantine time. The NIRS XDS SmartProbe process, and minimize laboratory analysis times. The Analyzer is ruggedly manufactured for either the NIRS XDS Transmission OptiProbe Analyzer is designed warehouse or plant environments. The ergonomic, hand-for laboratory monitoring of aqueous products, clear held design is straightforward; simply place the probe in liquids and solvents, as well as viscous samples. The NIRS the sample and press the trigger. Pass/fail results are dis-XDS Transmission OptiProbe Analyzer is well-suited for played on the handle after each test. scale-up process applications and atline measurements. Determinations of viscous samples can be carried out easily with this analyzer using disposable vials, thus reducing the amount of cleanup time to a minimum. With the optional Vial Heater Module, the system also provides automatic sample temperature equilibration prior to data analysis, thus increasing laboratory efficiency. Ordering Information 2.921.1510 NIRS XDS Interactance OptiProbe Analyzer 2.921.1520 NIRS XDS Transmission OptiProbe Analyzer 2.921.1530 NIRS XDS Transmission OptiProbe Analyzer – Heated Vials 2.921.1610 NIRS XDS SmartProbe Analyzer – 2 m Fiber 2.921.1620 NIRS XDS SmartProbe Analyzer – 3 m NIRS XDS SmartProbe Analyzer Fiber Near-infrared spectroscopy 123 Process analyzers Introduction NIR process analyzers offer information about chemical The length of the fiber optic interface can be from 1 m processes practically in real time, no matter how harsh (large fiber bundle) to 150 m (single fiber optic). The use the processing conditions may be. The process sample of longer fiber optic lengths enables a process analyzer interface is dictated by the sample type and process con-to be set up outside of electrically classified or safety ditions. Contact transmission and reflectance probes are classified areas or under harsh operating conditions such used for analyzing clear to opaque liquids and solids. as those with large temperature fluctuations. Up to nine separate process streams or sampling points can be Noncontact reflectance measurements are performed on monitored using a multiplexer NIR Process Analyzer from materials transported in hoppers, transport and conveyor Metrohm NIRSystems. Multiplexing decreases both the lines. Generally, NIR light from the instrument is trans-costs per measuring point and the overall implementation ferred to the process sample interface using fiber optics. costs for an NIR process analyzer. The number of fibers used in the fiber optic bundle is increased in order to maintain analytical performance as Metrohm NIRSystems analyzers, software, application the light scattering properties of the process sample support and services meet a full range of process industry increase. needs – process development, raw materials testing, process monitoring, endpoint determination, fluid bed Single-fiber process NIR analyzers are typically employed drying, quality control and stability testing. to analyze clear liquids. Microbundle process NIR analyzers monitor slightly scattering liquid media, suspensions, and drying processes. Full-bundle process NIR analyzers are used for the most challenging of applica- tions such as monitoring the drying of hydrated media or analyzing low-level constituents. Fiber optic interface Fiber size/count Fiber length [m] Sample type Mode 600 µm, Clear liquids, thin films, Single fiber 1–150 Transmission 1 illumination/1 collection gases 200 µm, Turbid liquids and Small fiber bundles 1–75 Transmission 40 illumination/40 collection suspensions 200 µm, Small fiber bundles 1–75 Powders and films Reflectance 40 illumination/40 collection 200 µm, Pastes, slurries, pellets, Large fiber bundles 1–15 Reflectance 210 illumination/210 collection fibers Comparison of fiber optic interface, fiber bundle size, and measurement mode. To maintain analytical performance, fiber count is increased as the turbidity of process sample increases. 124 Near-infrared spectroscopy NIRS XDS Process Analyzers – SingleFiber • Direct inline measurement yields real-time analysis and The analyzer is available as a single-point or a multiplexer data availability in seconds configuration. Two multiplexer process analyzer configu- • Interface made of simple optical fiber optimized for rations offer up to either four or nine sampling points. process streams, as with clear liquids and films This economical means of performing remote measure- • Single-point or multiplex analyzer (four or nine sample ments enables the analyzer to be installed in an unre-channels) stricted area, reducing installation and operation costs. • NEMA 4X/IP65 rated, ATEX ready The patented, robust design of NIRS XDS Process Ana- • Optional upgrade to hazardous area classification lyzers supplies a new level of consistent, dependable and reliable instrument performance and analysis while oper- The NIRS XDS Process Analyzer – SingleFiber belongs to ating in harsh industrial environments. the next generation of process analyzers for real-time analysis in the pharmaceutical and chemical industries. Nondestructive, accurate measurements are performed directly in the process line or in the reaction vessel. Typical measurements include reaction monitoring and end point determination in refinery, petrochemical and polymer processes, solvent recovery in pharmaceutical API plants, and analysis of extruded polymer films and coatings. The use of single fiber optics and the associated probes and flow-through cells allows for cost-effective analysis of a wide variety of sample types ranging from clear liquids to transparent films. Ordering Information 2.928.0210 NIRS XDS Process Analyzer – SingleFiber SinglePoint 2.928.0220 NIRS XDS Process Analyzer – SingleFiber 4 Channels 2.928.0230 NIRS XDS Process Analyzer – NIRS XDS Process Analyzer SingleFiber 9 Channels Near-infrared spectroscopy 125 NIRS XDS Process Analyzers – MicroBundle • Direct inline measurement for real-time analysis and with a reflectance probe, an immersion probe or a trans-data availability in seconds mission probe pair for an optimized interface to your • MicroBundle fiber optic interface, optimized for proc- particular sample type. ess stream: clear to opaque liquids, slurries, suspensions and powders The XDS Process Analyzer – MicroBundle is available as a • One sample channel or multiplexing of up to nine single-point or a multiplexer configuration for measure-channels ment of up to either four or nine sampling points. This • Fiber to analyzer connection via SMA fittings economical means of performing remote measurements • NEMA 4X/IP65 rated, ATEX ready enables the analyzer to be installed in an unrestricted • Optional upgrade to hazardous area classification area, reducing installation and operation costs. The NIRS XDS Process Analyzer – MicroBundle belongs to The patented, robust design of NIRS XDS Process Ana-the next generation of process analyzers for real-time lyzers supplies a new level of consistent, dependable and analysis in the pharmaceutical and chemical industries. reliable instrument performance and analysis while oper-Nondestructive, accurate measurements are performed ating in harsh industrial environments. Monitoring with directly in the process line, granulator, dryer or reaction near-infrared (NIR) fits in well with Process Analytical vessel. Technology (PAT) initiatives as proposed by the FDA. Process analyzers are used throughout the process stream to ensure optimum performance for many types of samples. The multi-fiber bundles used allow for cost- effective analysis of sample types ranging from clear liquids to suspensions and solids. Configure the analyzer Ordering Information 2.928.0110 NIRS XDS Process Analyzer – MicroBundle SinglePoint 2.928.0120 NIRS XDS Process Analyzer – MicroBundle 4 Channels 2.928.0130 NIRS XDS Process Analyzer – NIRS XDS Process Analyzer MicroBundle 9 Channels 126 Near-infrared spectroscopy NIRS XDS Process Analyzer – DirectLight/NonContact • Nondestructive inline near-infrared analysis (NIR) of the papers, and textiles. The measuring head is attached at moving product the terminal end of an optical fiber. A high-intensity light • Noncontact reflectance measurements directly in the source contained in the sensor head illuminates the product line sample. Light interacts with the sample and is reflected • Utilization above conveyor belts, webs for homogene- back to the sensor head, picked up by the collection fiber ous or nonhomogeneous products bundle, and passed on to the instrument for dispersion • Wavelength range from 800 to 2,200 nm and signal detection. The patented, robust design of the • NEMA 4X/IP65 rated, measuring head IP69K stainless NIRS XDS Process Analyzers supplies a higher level of steel consistent, reliable instrument performance and analysis for operation in harsh chemical environments. Based on NIR XDS technology, the NIRS XDS Process Analyzer – DirectLight/NonContact is numbered among the next generation of noncontact process analyzers for real-time analysis. Nondestructive, accurate measure- ments are performed wherever a product is moving and accessible, for instance, above a conveyor belt, web or sheet. Noncontact reflectance measurement can provide more detailed chemical analysis for loose to densely packed, homogeneous or nonhomogeneous solid products. Noncontact measurement is used for quality control of fibers, sheets, laminates, and web-based products like plastics, Ordering Information NIRS XDS Process Analyzer 2.928.0310 NIRS XDS Process Analyzer – DirectLight/NonContact Near-infrared spectroscopy 127 NIRS Analyzer PRO The NIRS Analyzer PRO is a process analyzer based on fiber. The light interacts with the sample and the reflect-high-resolution diode array technology. It provides non- ed or transmitted light is measured by the diode array destructive analysis of products such as granules, pow-sensor. The backup lamp in the dual-lamp system secures ders, slurries, or opalescent substances directly in the uptime and analytical accuracy is unchanged even after process line without bypass. switching to a new lamp. The analyzer is housed in a robust cabinet mounted at The complete wavelength range is measured instantane-the relevant location in the production area. Measure-ously enabling measurements also on fast moving sam- ments are displayed in the control room and results can ples with high accuracy. Calibrations are transferable be fed into a regulation system for closed-loop automatic between instruments, ensuring easy expansion to other control. Additionally, the analyzer helps to optimize the measuring points. Integration to process regulations sys-use of raw materials and to run production consistently tems can be done through the Metrohm OPC interface. closer to target specifications. Accurate instrument adjustment enhances method development, minimizes ContactReflection implementation requirements and ensures calibration Inline analyses of pastes, granules, powders, etc. in pipes model transferability between analyzers. or transport systems without bypass can be performed. The products pass over the interface window. The win- The NIRS Analyzer PRO is available with dedicated inter- dow reflection interface can easily be installed into the faces based on reflectance or transmittance technology production line either by using flow-through cells or by whichever is best suited for each application area. Meas-welding an interface flange into the wall of the pipe/ urements are done directly on the moving sample in the transport system. process stream. A high-intensity dual-lamp light source illuminates the sample directly or through an optical FiberSystem Process streams of clear to opaque liquids, slurries, suspensions and powders can be measured and optimized inline with this system. Depending on the sample type, the analyzer can be configured with fiber optic MicroBundle reflection or immersion probes. DirectLight/NonContact Inline analysis of products where direct contact with the product is not a technically feasible solution, i.e., products transported on a conveyor belt. Ordering Information 2.928.1110 NIRS Analyzer PRO – ContactReflection 2.928.1120 NIRS Analyzer PRO – FiberSystem 2.928.1130 NIRS Analyzer PRO – DirectLight/ NIRS Analyzer PRO NonContact 128 Near-infrared spectroscopy Ion chromatography Ion chromatography 129 130 Ion chromatography Ion chromatography Professional IC Vario – Systems 134 Professional IC Vario – Instruments 177 940 Professional IC Vario systems – Introduction 134 940 Professional IC Vario instruments – Introduction 177 Professional IC – ProfIC Vario systems 135 940 Professional IC Vario – Overview 178 How to find the right ProfIC Vario system 136 940 Professional IC Vario ONE 179 „ProfIC Vario 1 Cation“ 137 940 Professional IC Vario ONE/Prep 1 179 „ProfIC Vario 2 Cation“ 138 940 Professional IC Vario ONE/Prep 2 179 Metrohm Inline Ultrafiltration and Dialysis 139 940 Professional IC Vario ONE/HPG 179 „ProfIC Vario 3 Cation“ 140 940 Professional IC Vario ONE/LPG 180 „ProfIC Vario 4 Cation“ 141 940 Professional IC Vario ONE/ChS 180 „ProfIC Vario 5 Cation“ 142 940 Professional IC Vario ONE/ChS/HPG 180 „ProfIC Vario 6 Cation“ 143 940 Professional IC Vario ONE/ChS/LPG 180 „ProfIC Vario 7 Cation“ 144 940 Professional IC Vario ONE/ChS/PP 181 „ProfIC Vario 8 Cation“ 145 940 Professional IC Vario ONE/ChS/PP/HPG 181 „ProfIC Vario 9 Cation“ 146 940 Professional IC Vario ONE/ChS/PP/LPG 181 „ProfIC Vario 14 Cation“ 147 940 Professional IC Vario ONE/SeS 181 „ProfIC Vario 15 Cation“ 148 940 Professional IC Vario ONE/SeS/Prep 1 182 „ProfIC Vario 1 Anion“ 149 940 Professional IC Vario ONE/SeS/Prep 2 182 „ProfIC Vario 1 Anion DR“ 150 940 Professional IC Vario ONE/SeS/Prep 3 182 Suppression repeatability 151 940 Professional IC Vario ONE/SeS/HPG 182 Sequential suppression 152 940 Professional IC Vario ONE/SeS/LPG 183 „ProfIC Vario 2 Anion“ 153 940 Professional IC Vario ONE/SeS/PP 183 „ProfIC Vario 3 Anion“ 154 940 Professional IC Vario ONE/SeS/PP/Prep 1 183 „ProfIC Vario 4 Anion“ 155 940 Professional IC Vario ONE/SeS/PP/Prep 2 183 „ProfIC Vario 5 Anion“ 156 940 Professional IC Vario ONE/SeS/PP/Prep 3 184 „ProfIC Vario 6 Anion“ 157 940 Professional IC Vario ONE/SeS/PP/HPG 184 „ProfIC Vario 7 Anion“ 158 940 Professional IC Vario ONE/SeS/PP/LPG 184 „ProfIC Vario 8 Anion“ 159 940 Professional IC Vario TWO 184 „ProfIC Vario 9 Anion“ 160 940 Professional IC Vario TWO/ChS 185 „ProfIC Vario 10 Anion“ 161 940 Professional IC Vario TWO/ChS/PP 185 „ProfIC Vario 11 Anion“ 162 940 Professional IC Vario TWO/SeS 185 „ProfIC Vario 12 Anion“ 163 940 Professional IC Vario TWO/SeS/PP 185 „ProfIC Vario 14 Anion“ 164 Professional IC Vario – Detectors 186 „ProfIC Vario 15 Anion“ 165 IC Conductivity Detector 186 „ProfIC Vario 1 Amperometry“ 166 IC Amperometric Detector 186 „ProfIC Vario 1 UV/VIS“ 167 944 Professional UV/VIS Detector Vario 186 „ProfIC Vario 1 PCR-UV/VIS“ 168 945 Professional Detector Vario – Conductivity 186 „ProfIC Vario 1 AnCat“ 169 945 Professional Detector Vario – Amperometry 187 „ProfIC Vario 2 AnCat“ 170 945 Professional Detector Vario – Conductivity & „ProfIC Vario 4 AnCat“ 171 Amperometry 187 „ProfIC Vario 5 AnCat“ 172 Inline Eluent Preparation – Introduction 188 „ProfIC Vario 6 AnCat“ 173 941 Eluent Production Module 189 „ProfIC Vario 9 AnCat“ 174 „ProfIC Vario 14 AnCat“ 175 „ProfIC Vario 15 AnCat“ 176 Ion chromatography 131 Extension Module Vario – Overview 190 Professional IC Vario – Hyphenated systems 204 942 Extension Module Vario Prep 2 191 IC Vario coupling techniques – Introduction 204 942 Extension Module Vario HPG 191 TitrIC Vario pro I 205 942 Extension Module Vario LQH 191 TitrIC Vario pro II 205 942 Extension Module Vario ChS/PP 191 TitrIC Vario pro III 205 942 Extension Module Vario SeS/PP 192 VoltIC Vario pro I 205 942 Extension Module Vario ONE/Deg 192 930 Metrohm Combustion IC 206 920 Absorber Module 206 Compact IC Flex – Instruments 193 MMS 5000 Autosampler 206 Compact IC Flex – Introduction 193 Combustion Module ( Oven + ABD ) 206 Compact IC Flex – Overview 194 Auto Boat Drive 207 930 Compact IC Flex 195 LPG/GSS Module 207 930 Compact IC Flex Deg 195 Combustion Module (Oven + LPG/GSS) 207 930 Compact IC Flex ChS 195 PILS, Particle Into Liquid Sampler 207 930 Compact IC Flex ChS/Deg 195 MARGA 208 930 Compact IC Flex ChS/PP 196 930 Compact IC Flex ChS/PP/Deg 196 Automation in ion chromatography 209 930 Compact IC Flex SeS 196 Overview of IC automation 209 930 Compact IC Flex SeS/Deg 196 858 Professional Sample Processor 210 930 Compact IC Flex SeS/PP 197 858 Professional Sample Processor – Pump 210 930 Compact IC Flex SeS/PP/Deg 197 858 Professional Sample Processor – Pump – 930 Compact IC Flex Oven 197 Injector 210 930 Compact IC Flex Oven/Deg 197 919 IC Autosampler plus 210 930 Compact IC Flex Oven/ChS 198 863 Compact IC Autosampler 211 930 Compact IC Flex Oven/ChS/Deg 198 815 Robotic Soliprep for LC 211 930 Compact IC Flex Oven/ChS/PP 198 889 IC Sample Center 211 930 Compact IC Flex Oven/ChS/PP/Deg 198 889 IC Sample Center – cool 211 930 Compact IC Flex Oven/SeS 199 Additional Sample Processors for IC 212 930 Compact IC Flex Oven/SeS/Deg 199 930 Compact IC Flex Oven/SeS/PP 199 930 Compact IC Flex Oven/SeS/PP/Deg 199 Basic IC plus – Instruments 200 883 Basic IC plus 200 883 Basic IC plus Package 200 Additional IC Vario components 201 Alternative IC components – Introduction 201 Heatable reactors and column compartments 202 943 Professional Reactor Vario 202 943 Professional Thermostat Vario 202 Data Converters 203 771 IC Compact Interface 203 771 IC Compact Interface; MagIC Net Professional 203 771 IC Compact Interface; MagIC Net Compact 203 891 Professional Analog Out 203 132 Ion chromatography Liquid Handling in ion chromatography 213 Liquid Handling in IC – Introduction 213 800 Dosino 214 846 Dosing Interface 214 IC equipment: Additional eluent on the Eluent Production Module 214 IC equipment: Inline dialysis 214 IC equipment: Inline ultrafiltration 215 IC equipment: Inline dilution 215 IC equipment: Liquid Handling Station, left 215 IC equipment: MiPCT 215 IC equipment: Dose-in Gradient 216 IC equipment: MiPCT-ME 216 IC equipment: MiPUT 216 IC equipment: MiPT 216 IC equipment: Dosino regeneration 217 IQ/OQ Kit for IC 217 IC equipment for Liquid Handling Set for PILS 217 Peristaltic pump, 8-channel 217 Professional Vario IC – Software 218 MagIC Net – Introduction 218 MagIC Net 3.0 Compact CD: 1 license 219 MagIC Net 3.0 Professional CD: 1 license 219 MagIC Net 3.0 Multi CD: 3 licenses 219 Metrohm IC Driver for Empower 219 Ion chromatography 133 Professional IC Vario – Systems 940 Professional IC Vario systems – Introduction Intelligent ion chromatography ware. Optimum operation of the 940 Professional IC The 940 Professional IC Vario is the second generation of Vario and the results are both monitored. If a parameter professional ion chromatography systems with intelligent lies outside of the specified range, then the user will be system components that are optimally coordinated with informed via e-mail or SMS. The 940 Professional IC Vario one another. The path from the sample to the precise is a complex and very high-performance system for result has become simpler, as the system itself is thinking which simple and intuitive operation is provided by the during the procedure and even making logical decisions. MagIC Net software. This applies for experienced users with complex applications and sophisticated calculations • Intelligence in the hardware of the 940 Professional IC as well as for users who value „one-button operation“. Vario: Every user level is possible. Innovation, flexibility and - iPump exceptionally simple operation result from the intelli- - iDetector gence of the 940 Professional IC Vario, the 942 Extension - iReactor Module Vario, the 858 Professional Sample Processor - iCell and the MagIC Net software. - intelligent Dosino • Intelligence in the MagIC Net software Online configurator • Intelligence in the Metrosep iColumns With just a few mouseclicks, this software tool can be used to configure any imaginable IC system down to the These are the intelligent system components that moni- last detail. The path to the tailored solution for individual tor all functions, optimize them and, if desired, also requirements in ion chromatography has thus become document them in accordance with FDA requirements. even simpler. The configuration of the system is as simple as possible, as the components log in automatically and make all It is precisely here that the new online configurator pro-relevant information available to the MagIC Net soft-vides the user with support. Starting from the analysis requirements, the user selects the necessary modules from the comprehensive ion chromatography array on offer from Metrohm and specifies a system, step by step, that optimally meets his requirements. Once the solution has been specified down to the last detail, the user can print out „his“ system as a photo-realist graph in PDF format. In addition, he receives a detailed list of the modules and components contained in the respective system along with their order numbers. Access to the new online configurator is through ic940. metrohm.com 134 Ion chromatography Professional IC – ProfIC Vario systems The „ProfIC Vario“ systems are assemblies of Professional IC instruments and accessory parts that are custom- tailored for a particular application group. These systems contain all of the components required to perform the respective application with complete automation. The main components are: • 940 Professional IC Vario • IC Conductivity Detector • IC Amperometric Detector • 944 Professional UV/VIS Detector Vario • 945 Professional Detector Vario • 858 Professional Sample Processor • 942 Extension Module Vario • 800 Dosino In the respectively required versions with the correspond- ing accessory parts. Not included in the scope of delivery are the separation column, suppressor rotor, MagIC Net, the sample rack and the sample vessels. This ensures the greatest possible flexibility of the systems. No matter whether it be determination of anions in the analytical service laboratory with very high sample throughput or the detection of cations in the ultratrace range, as is required in nuclear power plants, the ProfIC Vario systems offer customized solutions for even the most sophisticated measurements in ion chromatography. 37 systems can be called up at www.metrohm.com/ com/Produkte2/IC/ProfIC-Vario-Systems.html. Ion chromatography 135 How to find the right ProfIC Vario system Step 1 Step 2 Step 3 Step 4 Result Matrix Concentration Anions Unloaded ppt ... ppb Ultratrace ProfIC Vario 9 Anion Trace ProfIC Vario 5 Anion ppb ... ppm Ful Loop Injection ProfIC Vario 1 Anion Partial Loop Injection ProfIC Vario 15 Anion ppm ... % ProfIC Vario 4 Anion Moderately loaded with ppb ... ppm ProfIC Vario 2 Anion particles ppm ... % ProfIC Vario 6 Anion Loaded with particles ppb ... ppm ProfIC Vario 3 Anion ppm ... % ProfIC Vario 7 Anion Loaded with a dissolved ppt ... ppb ProfIC Vario 9 Anion neutral matrix ppb ... ppm ProfIC Vario 8 Anion Loaded with a dissolved ppt ... ppb ProfIC Vario 11 Anion catonic matrix ppb ... ppm ProfIC Vario 10 Anion Online monitoring ProfIC Vario 12 Anion Limited sample ProfIC Vario 14 Anion Anions and cations Unloaded ppt…ppb Ultratrace ProfIC Vario 9 AnCat Trace ProfIC Vario 5 AnCat ppb…ppm Ful Loop Injection ProfIC Vario 1 AnCat Partial Loop Injection ProfIC Vario 15 AnCat ppm…% ProfIC Vario 4 AnCat Moderately loaded with ppb…ppm ProfIC Vario 2 AnCat particles ppm…% ProfIC Vario 6 AnCat Loaded with a dissolved neutral matrix ProfIC Vario 9 AnCat Limited sample ProfIC Vario 14 AnCat Cations Unloaded ppt ... ppb Ultratrace ProfIC Vario 9 Cation Trace ProfIC Vario 5 Cation ppb ... ppm Ful Loop Injection ProfIC Vario 1 Cation Partial Loop Injection ProfIC Vario 15 Cation ppm ... % ProfIC Vario 4 Cation Moderately loaded with ppb ... ppm ProfIC Vario 2 Cation particles ppm ... % ProfIC Vario 6 Cation Loaded with particles ppb ... ppm ProfIC Vario 3 Cation ppm ... % ProfIC Vario 7 Cation Loaded with a dissolved ppt ... ppb ProfIC Vario 9 Cation neutral matrix ppb ... ppm ProfIC Vario 8 Cation Limited sample ProfIC Vario 14 Cation 136 Ion chromatography „ProfIC Vario 1 Cation“ – Professional IC Vario system for automated ion chromatography The Professional IC Vario system with direct conductiv- Technical Information ity detection enables the fully automated determination Parts of cations or anions (non-suppressed). 1 x 2.940.1100 940 Professional IC Vario ONE 1 x 2.850.9010 IC Conductivity Detector Typical areas of application: 1 x 2.858.0020 858 Professional Sample Processor • Universal application for cation analysis • Routine analysis with large numbers of samples with- out additional sample preparation • Coupling with MS or ICP/MS instruments for research and development tasks The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for The „ProfIC Vario 1 Cation“ is comprised of the 940 Pro- volumes in the range of 0.5 - 500 mL. fessional IC Vario ONE, one „iDetector“ intelligent con- ductivity detector and one 858 Professional Sample The following components must be ordered separately in Processor. accordance with the desired application: • Separation column The 940 Professional IC Vario ONE is equipped with the • Sample rack „ONE“ module. It contains automatic sample and eluent • MagIC Net degassing, „iPump“ IC high-pressure pump with intelligent pump head, pulsation absorber, six-way injection valve with Maltese cross drive, column thermostat for cooling and heating two iColumns and an external column position in the room temperature range. Ordering Information „ProfIC Vario 1 Cation“ ProfIC Vario 1 Cation Ion chromatography 137 „ProfIC Vario 2 Cation“ – Professional IC Vario system with Inline Ultrafiltration The Professional IC Vario system with Metrohm Inline Technical Information Ultrafiltration and conductivity detection enables Parts the fully automatic determination of cations or anions 1 x 2.940.1100 940 Professional IC Vario ONE (non-suppressed). 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 6.5330.110 IC equipment: Inline Ultrafiltration • Samples with slight to medium-severe loads of parti- cles, algae or bacteria • Drinking and surface water • Process and waste water The IC equipment for Inline Ultrafiltration contains all of The „ProfIC Vario 2 Cation“ is comprised of one 940 the parts needed for integrating Metrohm Inline Ultra-Professional IC Vario ONE, one „iDetector“ intelligent filtration in the system. conductivity detector, one 858 Professional Sample Proc- essor and an IC equipment for Inline Ultrafiltration. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample The 940 Professional IC Vario ONE is equipped with the Processor. A minimum of 5 mL of sample is required for „ONE“ module. It contains automatic sample and eluent the Inline Ultrafiltration. degassing, „iPump“ IC high-pressure pump with intelligent pump head, pulsation absorber, six-way injection The following components must be ordered separately in valve with Maltese cross drive, column thermostat for accordance with the desired application: cooling and heating two iColumns and an external • Separation column column position in the room temperature range. • Sample rack • MagIC Net Ordering Information „ProfIC Vario 2 Cation“ ProfIC Vario 2 Cation 138 Ion chromatography Metrohm Inline Ultrafiltration and Dialysis Metrohm Inline Ultrafiltration Metrohm Inline Dialysis In modern ion chromatography, it is recommended that More severely loaded samples require complex and al samples be filtered before injection. Separation work-intensive preparatory steps prior to their actual columns with particle sizes of less than 10 µm require determination. For this, Metrohm Inline Dialysis permits a absolutely particle-free sample solutions. Unfiltered solu-significant rationalization of the entire analysis. The only tions can lead to pressure increases on the column and condition the sample must meet: It must be present in thus to a certain extent to a massively shortened lifetime liquid form or be able to be transformed into one and be for the separation column. The usual manual filtration largely homogenous. Larger-sized particles are also to be takes place with disposable filter cartridges with pore removed with centrifuging. Afterwards, the sample solu-sizes of 0.45 µm or smaller. These become blocked very tion is dialyzed in the dialysis cell in accordance with the quickly, particularly with samples containing minuscule method patented by Metrohm (European Patent 0 820 particles. As an alternative, sample changers are also 804, US Patent 5,861,097). Practically complete dialysis used with filter caps. Here the pore size is often larger is achieved, thanks to this special „Inline Stopped Flow than it is with the disposable filters. These are expensive Dialysis“ method. That means that the acceptor solution and there is also a danger of blockage associated with exhibits the same ion concentration as the original sam-them. These problems are a thing of the past with Met- ple (equilibrium dialysis). Afterwards, the acceptor rohm Inline Ultrafiltration, a membrane separation tech- solution is injected directly into the ion chromatograph nique. The samples are placed directly on the turntable. and analyzed. In the case of ultrafiltration, a pressure The sample stream is guided into the lower chamber of differential causes the sample solution to be filtered the ultrafiltration cell and along the membrane to the through the membrane, but with dialysis it is the differ-waste container at the time the samples are processed. ence in concentration between the two sides that is the The peristaltic pump generates an underpressure in the driving force. The ions to be determined diffuse through upper chamber of the cell, thus causing the sample solu-the membrane, but no sample solution is pressed tion to be suctioned through the ultrafiltration membrane. through the membrane. Accordingly, no filter cake is The filtered sample solution reaches the injection loop formed that could block the membrane. With the aid of and is subsequently injected. Less than 20% of the origi-this technology, it is possible to determine anions and nal solution is removed as filtrate, the remainder flows cations, even in cutting oil emulsions, biodiesel, milk directly into the waste. The formation of a filter cake that products or bodily fluids such as blood and urine. If the could lead to a jamming of the membrane is largely pre-system is programmed in such a way that the next sam- vented by this and by the geometric alignment of the ple is dialyzed during the current run, then the total cell. Metrohm Inline Ultrafiltration is especially suitable analysis time corresponds to that of a direct injection. for samples with small to medium loads, e.g., drinking water, surface water, sewage, digestion solutions, extractions. «Stopped flow» method. An equilibrium is achieved between Ultrafiltration the acceptor solution and the sample solution Ion chromatography 139 „ProfIC Vario 3 Cation“ – Professional IC Vario system with Inline Dialysis The Professional IC Vario system with Metrohm inline Technical Information dialysis and conductivity detection enables the fully Parts automatic determination of cations or anions (non-sup- 1 x 2.940.1110 940 Professional IC Vario ONE/Prep 1 pressed). 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 6.5330.100 IC equipment: Inline Dialysis • Samples with severe loads of particles, algae or bacte- ria • Process, wash and waste water column thermostat for cooling and heating two iCol- • Emulsions, dispersions, cutting oils and samples con-umns and an external column position in the room tem- taining petroleum perature range. • Milk products and other samples containing protein In addition, a bidirectional two-channel peristaltic pump The „ProfIC Vario 3 Cation“ is comprised of one 940 for sample preparation or sample injection is located in Professional IC Vario ONE/Prep 1, one „iDetector“ intelli-the lower segment of the instrument („Prep 1“). The gent conductivity detector, one 858 Professional Sample position for the installation of the dialysis cell is prepared Processor and one IC equipment for Inline Dialysis. here. The 940 Professional IC Vario ONE/Prep 1 is equipped The IC equipment for Inline Dialysis contains all of the with the „ONE“ and „Prep 1“ modules. It contains auto-parts required for the Metrohm-patented „Inline Stopped matic sample and eluent degassing, „iPump“ IC high- Flow Dialysis“. pressure pump with intelligent pump head, pulsation absorber, six-way injection valve with Maltese cross drive, Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. At least 10 mL of sample are required for Inline Dialysis. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 3 Cation“ ProfIC Vario 3 Cation 140 Ion chromatography „ProfIC Vario 4 Cation“ – Professional IC Vario system with Inline Dilution The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Inline Dilution and conductivity detection Parts enables the fully automatic determination of cations or 1 x 2.940.1100 940 Professional IC Vario ONE anions (non-suppressed) in concentrated solutions. 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 2.741.0010 741 Magnetic Stirrer • Samples with high ion concentration 1 x 2.800.0010 800 Dosino • Samples from all industries 1 x 6.5330.120 IC equipment: Inline Dilution The „ProfIC Vario 4 Cation“ is comprised of one 940 Professional IC Vario ONE, one „iDetector“ intelligent conductivity detector, one 741 Magnetic Stirrer, one 800 The „ProfIC Vario 4 Cation“ offers the option of automat-Dosino and one IC equipment for Inline Dilution. ed inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Proces-The 940 Professional IC Vario ONE is equipped with the sor. The 800 Dosino aspirates the volume to be diluted „ONE“ module. It contains automatic sample and eluent into the transfer tubing, doses it into the Liquid Handling degassing, „iPump“ IC high-pressure pump with intelli-Station and adds the required volume of dilution medi- gent pump head, pulsation absorber, six-way injection um. All of the parts required are on hand with the IC valve with Maltese cross drive, column thermostat for equipment for Inline Dilution. cooling and heating two iColumns and an external column position in the room temperature range. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 4 Cation“ ProfIC Vario 4 Cation Ion chromatography 141 „ProfIC Vario 5 Cation“ – Professional IC Vario system with Metrohm‘s intelligent preconcentration technique (MiPCT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent inline sample preconcentration and conduc- Parts tivity detection enables the fully automatic determina-1 x 2.940.1100 940 Professional IC Vario ONE tion of cations or anions (non-suppressed) in solutions 1 x 2.850.9010 IC Conductivity Detector with low ion concentration. 1 x 2.858.0010 858 Professional Sample Processor 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.140 IC equipment: MiPCT • Numerous applications, ranging from ultrapure water analysis to drinking water analysis • Analyses of different samples from power plants valve with Maltese cross drive, column thermostat for • Process control and monitoring of rinsing solutions, cooling and heating two iColumns and an external e.g., in the semiconductor industry column position in the room temperature range. The „ProfIC Vario 5 Cation“ is comprised of one 940 With the 800 Dosino and the IC equipment for MiPCT, all Professional IC Vario ONE, one „iDetector“ intelligent of the parts required for Metrohm‘s intelligent precon-conductivity detector, one 800 Dosino, one 858 Profes- centration technique are on hand. sional Sample Processor and one IC equipment for MiPCT. The 858 Professional Sample Processor makes the sam- ples available. The transfer takes place with the 800 The 940 Professional IC Vario ONE is equipped with the Dosino. Numerous sample racks are available for volumes „ONE“ module. It contains automatic sample and eluent in the range of 0.5 - 500 mL. degassing, „iPump“ IC high-pressure pump with intelligent pump head, pulsation absorber, six-way injection The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 5 Cation“ ProfIC Vario 5 Cation 142 Ion chromatography „ProfIC Vario 6 Cation“ – Professional IC Vario system with Inline Dilution and Inline Ultrafiltration The Professional IC Vario system with Metrohm Inline Technical Information Dilution, Metrohm Inline Ultrafiltration and con- Parts ductivity detection enables the fully automatic deter-1 x 2.940.1100 940 Professional IC Vario ONE mination of cations or anions (non-suppressed) that are 1 x 2.850.9010 IC Conductivity Detector present in very high concentrations and that have matri- 1 x 2.858.0020 858 Professional Sample Processor ces containing particles. 1 x 2.741.0010 741 Magnetic Stirrer 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.120 IC equipment: Inline Dilution • Rinse, process and waste water 1 x 6.5330.110 IC equipment: Inline Ultrafiltration • Extractions and digestion solutions • Food samples valve with Maltese cross drive, column thermostat for The „ProfIC Vario 6 Cation“ is comprised of one 940 cooling and heating two iColumns and an external Professional IC Vario ONE, one „iDetector“ intelligent column position in the room temperature range. conductivity detector, one 741 Magnetic Stirrer, one 800 Dosino, one 858 Professional Sample Processor, an IC The „ProfIC Vario 6 Cation“ offers the option of auto-equipment for Inline Dilution and an IC equipment for mated inline dilution of every sample. This takes place at Inline Ultrafiltration. an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be The 940 Professional IC Vario ONE is equipped with the diluted into the transfer tubing, doses it into the Liquid „ONE“ module. It contains automatic sample and eluent Handling Station and adds the required volume of dilu-degassing, „iPump“ IC high-pressure pump with intelli-tion medium. All of the parts required are on hand with gent pump head, pulsation absorber, six-way injection the IC equipment for Inline Dilution. The IC equipment for Inline Ultrafiltration contains all of the parts needed for integrating the subsequent Metrohm Inline Ultrafiltration in the system. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 6 Cation“ ProfIC Vario 6 Cation Ion chromatography 143 „ProfIC Vario 7 Cation“ – Professional IC Vario system with Inline Dilution and Inline Dialysis The Professional IC Vario system with Metrohm Inline Technical Information Dilution, Inline Dialysis and conductivity detection Parts enables the fully automated determination of cations or 1 x 2.940.1110 940 Professional IC Vario ONE/Prep 1 anions (non-suppressed) that are present in high concen- 1 x 2.850.9010 IC Conductivity Detector trations and in difficult matrices. 1 x 2.858.0020 858 Professional Sample Processor 1 x 2.741.0010 741 Magnetic Stirrer Typical areas of application: 1 x 2.800.0010 800 Dosino • Process, wash and waste water 1 x 6.5330.120 IC equipment: Inline Dilution • Samples containing oil 1 x 6.5330.100 IC equipment: Inline Dialysis • Inline Extraction for biodiesel analysis The „ProfIC Vario 7 Cation“ is comprised of one 940 column thermostat for cooling and heating two iCol-Professional IC Vario ONE/Prep 1, one „iDetector“ intelli- umns and an external column position in the room tem- gent conductivity detector, one 741 Magnetic Stirrer, one perature range. 800 Dosino, one 858 Professional Sample Processor, an IC equipment for Inline Dilution and an IC equipment for In addition, a bidirectional two-channel peristaltic pump Inline Dialysis. for sample preparation or sample injection is located in the lower segment of the instrument („Prep 1“). The The 940 Professional IC Vario ONE/Prep 1 is equipped position for the installation of the dialysis cell is prepared with the „ONE“ and „Prep 1“ modules. It contains auto-here. matic sample and eluent degassing, „iPump“ IC high- pressure pump with intelligent pump head, pulsation The „ProfIC Vario 7 Cation“ offers the option of automat-absorber, six-way injection valve with Maltese cross drive, ed inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be diluted into the transfer tubing, doses it into the Liquid Handling Station and adds the required volume of dilution medium. All of the parts required are on hand with the IC equipment for Inline Dilution. The IC equipment for Inline Dialysis contains all of the parts required for the subsequent Metrohm-patented „Inline Stopped Flow Dialysis“. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 7 Cation“ ProfIC Vario 7 Cation 144 Ion chromatography „ProfIC Vario 8 Cation“ – Professional IC Vario system with Inline Matrix Elimination The Professional IC Vario system with Metrohm Inline Technical Information Matrix Elimination and conductivity detection ena-Parts bles the determination of cations or anions (non-sup-1 x 2.940.1100 940 Professional IC Vario ONE pressed) in difficult matrices. 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0030 858 Professional Sample Processor Typical areas of application: 1 x 6.1602.150 Bottle attachment / GL 45 - 3 × UNF • Trace analysis in polar solvents 1 x 6.1608.070 Eluent bottle / 2 L / GL 45 • Quality controls in fuels, fuel mixtures and biofuels 1 x 6.1825.230 PEEK sample loop 10 µL • Quality management of chemicals The „ProfIC Vario 8 Cation“ is comprised of one 940 The injector and the peristaltic pump on the 858 Profes-Professional IC Vario ONE, one „iDetector“ intelligent sional Sample Processor and the additional accessory conductivity detector and one 858 Professional Sample parts enable Inline Matrix Elimination. Numerous sample Processor. racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. The 940 Professional IC Vario ONE is equipped with the As a rule, only small volumes with a maximum of 1 mL „ONE“ module. It contains automatic sample and eluent sample are required for matrix elimination. degassing, „iPump“ IC high-pressure pump with intelligent pump head, pulsation absorber, six-way injection The following components must be ordered separately in valve with Maltese cross drive, column thermostat for accordance with the desired application: cooling and heating two iColumns and an external • Separation column column position in the room temperature range. • Preconcentration column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 8 Cation“ ProfIC Vario 8 Cation Ion chromatography 145 „ProfIC Vario 9 Cation“ – Professional IC Vario system with Metrohm‘s intelligent preconcentration technique and Inline Matrix Elimination (MiPCT-ME) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent inline preconcentration technique, Inline Parts Matrix Elimination and conductivity detection ena-1 x 2.940.1100 940 Professional IC Vario ONE bles ultratrace analysis down to the lowest ppt range 1 x 2.850.9010 IC Conductivity Detector (ng/L) of cations in complex matrices. 1 x 2.858.0010 858 Professional Sample Processor 2 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.160 IC equipment: MiPCT-ME • Ultratrace analysis in samples from nuclear power plants and conventional power plants • Trace and ultratrace analysis in extraction agents and valve with Maltese cross drive, column thermostat for organics cooling and heating two iColumns and an external • Trace analysis in snow and ice column position in the room temperature range. The „ProfIC Vario 9 Cation“ is comprised of one 940 The two 800 Dosinos and the IC equipment for MiPCT-Professional IC Vario ONE, one „iDetector“ intelligent ME enable preconcentration of the sample and subse-conductivity detector, one 858 Professional Sample quent matrix elimination. Typical preconcentration vol-Processor, two 800 Dosinos and one IC equipment for umes are 4 - 4,000 µL. MiPCT-ME. The 858 Professional Sample Processor makes the sam- The 940 Professional IC Vario ONE is equipped with the ples available. Numerous sample racks are available for „ONE“ module. It contains automatic sample and eluent volumes in the range of 0.5 - 500 mL. degassing, „iPump“ IC high-pressure pump with intelligent pump head, pulsation absorber, six-way injection The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 9 Cation“ ProfIC Vario 9 Cation 146 Ion chromatography „ProfIC Vario 14 Cation“ – Professional IC Vario system with Metrohm‘s intelligent Pick-up-Injection Technique (MiPuT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Pick-up Injection Technique (MiPuT) and con- Parts ductivity detection enables the determination of 1 x 2.940.1100 940 Professional IC Vario ONE cations or anions (non-suppressed) from the smallest of 1 x 2.850.9010 IC Conductivity Detector sample volumes. 1 x 2.858.0020 858 Professional Sample Processor 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.170 IC equipment: MiPuT • For universal application for all types of samples when only small sample quantities are available • Investigation of biochemical processes cooling and heating two iColumns and an external • Environmental sample extracts column position in the room temperature range. The „ProfIC Vario 14 Cation“ is comprised of one 940 The 800 Dosino and the IC equipment for MiPuT enable Professional IC Vario ONE, one „iDetector“ intelligent Metrohm‘s intel igent Pick-up Injection Technique. conductivity detector, one 858 Professional Sample Proc- 2 - 50 µL of the samples can be removed and injected essor, one 800 Dosino and one IC equipment for MiPuT. directly. The 940 Professional IC Vario ONE is equipped with the Numerous sample racks are available for volumes in the „ONE“ module. It contains automatic sample and eluent range of 0.5 - 500 mL for the 858 Professional Sample degassing, „iPump“ IC high-pressure pump with intelli-Processor. gent pump head, pulsation absorber, six-way injection valve with Maltese cross drive, column thermostat for The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack (recommended 6.2041.480 Sample rack 159 x 2 mL + 3 x 300 mL) • MagIC Net Ordering Information „ProfIC Vario 14 Cation“ ProfIC Vario 14 Cation Ion chromatography 147 „ProfIC Vario 15 Cation“ – Professional IC Vario system with Metrohm‘s intelligent Partial Loop Injection Technique (MiPT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Partial Loop Injection Technique and con- Parts ductivity detection enables the fully automatic deter-1 x 2.940.1100 940 Professional IC Vario ONE mination of cations or anions (non-suppressed). „Partial 1 x 2.850.9010 IC Conductivity Detector Loop Injection“ enables the injection of various sample 1 x 2.858.0010 858 Professional Sample Processor volumes. 1 x 2.800.0010 800 Dosino 1 x 6.5330.180 IC equipment: MiPT Typical areas of application: • For universal application for all types of samples • From trace analysis to waste water analysis cooling and heating two iColumns and an external • Great differences in concentration in a single sample column position in the room temperature range. series The 800 Dosino and the IC equipment for MiPT enable The „ProfIC Vario 15 Cation“ is comprised of one 940 Metrohm‘s intelligent Partial Loop Injection Technique. Professional IC Vario ONE, one „iDetector“ intelligent 2 - 200 µL can be injected. conductivity detector, one 858 Professional Sample Proc- essor, one 800 Dosino and the IC equipment for MiPT. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample The 940 Professional IC Vario ONE is equipped with the Processor. „ONE“ module. It contains automatic sample and eluent degassing, „iPump“ IC high-pressure pump with intelli-The following components must be ordered separately in gent pump head, pulsation absorber, six-way injection accordance with the desired application: valve with Maltese cross drive, column thermostat for • Separation column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 15 Cation“ ProfIC Vario 15 Cation 148 Ion chromatography „ProfIC Vario 1 Anion“ – Professional IC Vario system for automated ion chromatography The Professional IC Vario system with sequential sup- Technical Information pression and conductivity detection enables the fully Parts automatic determination of anions. 1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP 1 x 2.850.9010 IC Conductivity Detector Typical areas of application: 1 x 2.858.0020 858 Professional Sample Processor • Universally applicable anion analysis • Routine analysis with large numbers of samples with- out additional sample preparation ture range and a bidirectional two-channel peristaltic • Coupling with MS or ICP/MS instruments for research pump. and development tasks The instrument is equipped with the drive for the „MSM, The „ProfIC Vario 1 Anion“ is comprised of one 940 Pro- MSM-HC and MSM-LC“ Metrohm Suppressor Module for fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent chemical suppression and the „MCS“ Metrohm CO Sup-2 conductivity detector and one 858 Professional Sample pressor for CO suppression. The combination of the two 2 Processor. suppressors represents a sequential suppression and per- mits very sensitive analyses, thanks to the extremely low The 940 Professional IC Vario ONE/SeS/PP is equipped background conductivity. The suppressor rotor is not pre-with the „ONE“ and „SeS/PP“ modules. It contains auto- mounted. This gives the customer different options to matic sample and eluent degassing, „iPump“ IC high-choose from and the suppressor rotor can be used in pressure pump with intelligent pump head, pulsation accordance with the respective application. absorber, six-way injection valve with Maltese cross drive, column thermostat for cooling and heating two iCol-The 858 Professional Sample Processor takes care of the umns, an external column position in the room tempera- sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 1 Anion“ ProfIC Vario 1 Anion Ion chromatography 149 „ProfIC Vario 1 Anion DR“ – Professional IC Vario system for automated ion chromatography with Dosino Regeneration of the suppressor The Professional IC Vario system with sequential sup- Technical Information pression with Dosino Regeneration of the suppressor Parts and conductivity detection enables the fully automatic 1 x 2.940.1400 940 Professional IC Vario ONE/SeS determination of anions. 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 2.800.0010 800 Dosino • Universally applicable anion analysis 1 x 6.5330.190 IC equipment: Dosino Regeneration • Routine analysis with large numbers of samples with- out additional sample preparation • Coupling with MS or ICP/MS instruments for research thermostat for cooling and heating two iColumns and an and development tasks external column position in the room temperature range. The „ProfIC Vario 1 Anion DR“ is comprised of one 940 The instrument is equipped with the drive for the „MSM, Professional IC Vario ONE/SeS, one „iDetector“ intelligent MSM-HC and MSM-LC“ Metrohm Suppressor Module for conductivity detector, one 800 Dosino, the 858 Profes-chemical suppression and the „MCS“ Metrohm CO Sup- 2 sional Sample Processor and the IC equipment for Dosino pressor for CO suppression. The combination of the two 2 Regeneration. suppressors represents a sequential suppression and per- mits very sensitive analyses, thanks to the extremely low The 940 Professional IC Vario ONE/SeS is equipped with background conductivity. The suppressor rotor is not pre-the „ONE“ and „SeS“ modules. It contains automatic mounted. This gives the customer different options to sample and eluent degassing, „iPump“ IC high-pressure choose from and the suppressor rotor can be used in pump with intelligent pump head, pulsation absorber, accordance with the respective application. The regener-six-way injection valve with Maltese cross drive, column ation of the MSM is performed with one Dosino. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 1 Anion DR“ ProfIC Vario 1 Anion DR 150 Ion chromatography Suppression repeatability A fresh suppressor cartridge is used for each measurement with the „MSM“ Metrohm Suppressor Module. This ensures that one is always working with a cation exchanger that provides full performance: uninterrupted use today, tomorrow and for years into the future. The suppressor is distinguished by its pressure stability, it is 100% solvent-resistant and captivates by the length of its lifetime. Because no sensitive membranes are used, the suppressor achieves equilibrium and is ready for use in no time at all. It is only this way that a 10-year guarantee can be provided for the „MSM“. The Metrohm Suppressor Module is inexpensive and robust. The fact that repeatability of the measurements with the „MSM“ is excellent is shown in the chromato- grams: 1 2 3 4 5 7 6 30 injections, separation of standard anions on the 1 Fluoride Metrosep A Supp 5 - 100/4.0, eluent 3.2 mmol/L 2 Chloride Na CO , 1.0 mmol/L NaHCO , flow 0.7 mL/min, 3 Nitrite 2 3 3 loop 20 µL, 45 °C, sequential suppression. 4 Bromide 5 Nitrate 6 Phosphate 7 Sulfate Ion Fluoride Chloride Nitrite Bromide Nitrate Phosphate Sulfate Concentration [mg/L] 0.25 0.25 0.25 0.25 0.25 0.25 0.25 Relative standard deviation in % (n = 30) 0.17 0.16 0.38 0.31 0.18 0.46 0.25 Ion chromatography 151 Sequential suppression Sequential suppression is the chemical suppression com- Drinking water from Herisau (Switzerland): comparison of bination using the „MSM, MSM-HC, MSM-LC“ with suppression with «MSM» (black) and with «MSM» plus Metrohm CO Suppression (MCS). This makes it possible «MCS» (red). 2 to detect anions with carbonate/hydrogen carbonate eluents at the low background conductivity of hydroxide eluents. The removal of CO prevents the carbonate equilibrium 2 from having a negative influence on the peak areas. The success: Up to 50% larger peak areas (and thus lower detection limits) result with the same concentration and the same sample volume. No carbonate peak also means no irritating interferences during the quantification of certain analyte anions. Chloride and carbonate coelute on many polystyrene-divinylbenzene columns, for example. This problem is now a thing of the past, thanks Column: Metrosep A Supp 5 - 100/4.0 (6.1006.510) to the use of the CO suppressor. Eluent: 3.2 mmol/L Na CO ; 1.0 mmol/L NaHCO 2 2 3 3 Flow rate: 0.4 mL/min The extensive absence of the injection peak improves the Nr. Ion Conz. (mg/L) determination of the rapidly eluting anions, e.g., of fluor-1 Injection peak – ide. Even though the separation of injection peak and 2 Fluoride 0.04 fluoride peak is already very good on polyalcohol columns, the detection limit can be improved even more 3 Chloride 7.79 when the CO suppressor is used. In addition, con- 4 Carbonate 2 siderably larger sample volumes can be input, as there is 5 Bromide 0.004 practically no injection peak more to be seen. 6 Nitrate 7.82 7 Sulfate 5.20 No suppressor rotor or SPM rotor has been pre-installed. The rotors can be ordered individually in accordance with the respective application. The table shows the order numbers and the respective main application. Suppressor rotor MSM 6.2832.000 Suppressor rotor for standard applications Rotor A Suppressor rotor for use with high-capacity MSM-HC 6.2842.000 columns or with long chromatogram Rotor A duration MSM-LC Suppressor rotor for use with 2 mm 6.2844.000 Rotor A separation columns SPM Rotor for inline sample preparation with 6.2835.000 Rotor A cation exchange 152 Ion chromatography „ProfIC Vario 2 Anion“ – Professional IC Vario system with Inline Ultrafiltration The Professional IC Vario system with Metrohm Inline Technical Information Ultrafiltration and conductivity detection enables Parts the fully automatic determination of anions. 1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP 1 x 2.850.9010 IC Conductivity Detector Typical areas of application: 1 x 2.858.0020 858 Professional Sample Processor • Samples with slight to medium-severe loads of parti- 1 x 6.5330.110 IC equipment: Inline Ultrafiltration cles, algae or bacteria • Drinking and surface water • Process and waste water column thermostat for cooling and heating two iCol- umns, an external column position in the room tempera- The „ProfIC Vario 2 Anion“ is comprised of one 940 Pro- ture range and a bidirectional two-channel peristaltic fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent pump. conductivity detector, one 858 Professional Sample Proc- essor and the IC equipment for Inline Ultrafiltration. The instrument is equipped with the drive for the „MSM, MSM-HC and MSM-LC“ Metrohm Suppressor Module for The 940 Professional IC Vario ONE/SeS/PP is equipped chemical suppression and the „MCS“ Metrohm CO Sup-2 with the „ONE“ and „SeS/PP“ modules. pressor for CO suppression. The combination of the two 2 suppressors represents a sequential suppression and per- The 940 Professional IC Vario ONE/SeS/PP can be used mits very sensitive analyses, thanks to the extremely low with or without chemical suppression. It contains auto-background conductivity. The suppressor rotor is not pre- matic sample and eluent degassing, „iPump“ IC high- mounted. This gives the customer different options to pressure pump with intelligent pump head, pulsation choose from and the suppressor rotor can be used in absorber, six-way injection valve with Maltese cross drive, accordance with the respective application. The IC equipment for Inline Ultrafiltration contains all of the parts needed for integrating Metrohm Inline Ultrafiltration in the system. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. A minimum of 5 mL of sample is required for the Inline Ultrafiltration. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 2 Anion“ ProfIC Vario 2 Anion Ion chromatography 153 „ProfIC Vario 3 Anion“ – Professional IC Vario system with Inline Dialysis The Professional IC Vario system with Metrohm Inline Technical Information Dialysis and conductivity detection enables the fully Parts automatic determination of anions. 1 x 2.940.1510 940 Prof. IC Vario ONE/SeS/PP/Prep 1 1 x 2.850.9010 IC Conductivity Detector Typical areas of application: 1 x 2.858.0020 858 Professional Sample Processor • Samples with severe loads of particles, algae or bacte- 1 x 6.5330.100 IC equipment: Inline Dialysis ria • Process, wash and waste water • Emulsions, dispersions, cutting oils and samples con-heating two iColumns, an external column position in taining petroleum the room temperature range and a bidirectional two- • Milk products and other samples containing protein channel peristaltic pump. The „ProfIC Vario 3 Anion“ is comprised of one 940 Pro- The instrument is equipped with the drive for the „MSM, fessional IC Vario ONE/SeS/PP/Prep 1, one „iDetector“ MSM-HC and MSM-LC“ Metrohm Suppressor Module for intelligent conductivity detector, one 858 Professional chemical suppression and the „MCS“ Metrohm CO Sup-2 Sample Processor and one IC equipment for Inline Dialy- pressor for CO suppression. The combination of the two 2 sis. suppressors represents a sequential suppression and per- mits very sensitive analyses, thanks to the extremely low The 940 Professional IC Vario ONE/SeS/PP/Prep 1 is background conductivity. The suppressor rotor is not pre-equipped with the „ONE“, „SeS/PP“ and „Prep 1“ mod- mounted. This gives the customer different options to ules. It contains automatic sample and eluent degassing, choose from and the suppressor rotor can be used in „iPump“ IC high-pressure pump with intelligent pump accordance with the respective application. head, pulsation absorber, six-way injection valve with Maltese cross drive, column thermostat for cooling and In addition, a bidirectional two-channel peristaltic pump for sample preparation or sample injection is located in the lower segment of the instrument („Prep 1“). The position for the installation of the dialysis cell is prepared here. The IC equipment for Inline Dialysis contains all of the parts required for the Metrohm-patented „Inline Stopped Flow Dialysis“. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. At least 10 mL of sample are required for Inline Dialysis. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 3 Anion“ ProfIC Vario 3 Anion 154 Ion chromatography „ProfIC Vario 4 Anion“ – Professional IC Vario system with Inline Dilution The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Inline Dilution and conductivity detection Parts enables the fully automatic determination of anions in 1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP concentrated solutions. 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 2.741.0010 741 Magnetic Stirrer • Samples with high ion concentration 1 x 2.800.0010 800 Dosino • Samples from all industries 1 x 6.5330.120 IC equipment: Inline Dilution The „ProfIC Vario 4 Anion“ is comprised of one 940 Pro- fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent conductivity detector, one 741 Magnetic Stirrer, one 800 The instrument is equipped with the drive for the „MSM, Dosino and one IC equipment for Inline Dilution. MSM-HC and MSM-LC“ Metrohm Suppressor Module for chemical suppression and the „MCS“ Metrohm CO Sup- 2 The 940 Professional IC Vario ONE/SeS/PP is equipped pressor for CO suppression. The combination of the two 2 with the „ONE“ and „SeS/PP“ modules. It contains auto- suppressors represents a sequential suppression and per- matic sample and eluent degassing, „iPump“ IC high- mits very sensitive analyses, thanks to the extremely low pressure pump with intelligent pump head, pulsation background conductivity. The suppressor rotor is not pre-absorber, six-way injection valve with Maltese cross drive, mounted. This gives the customer different options to column thermostat for cooling and heating two iCol-choose from and the suppressor rotor can be used in umns, an external column position in the room tempera-accordance with the respective application. ture range and a bidirectional two-channel peristaltic pump. The „ProfIC Vario 4 Anion“ offers the option of automatic inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be diluted into the transfer tubing, doses it into the Liquid Handling Station and adds the required volume of dilution medium. All of the parts required are on hand with the IC equipment for Inline Dilution. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 4 Anion“ ProfIC Vario 4 Anion Ion chromatography 155 „ProfIC Vario 5 Anion“ – Professional IC Vario system with Metrohm‘s intelligent preconcentration technique (MiPCT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent inline sample preconcentration and conduc- Parts tivity detection enables the fully automatic determina-1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP tion of anions in solutions with low ion concentration. 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0010 858 Professional Sample Processor Typical areas of application: 1 x 2.800.0010 800 Dosino • Numerous applications, ranging from ultrapure water 1 x 6.5330.140 IC equipment: MiPCT analysis to drinking water analysis • Analyses of different samples from power plants • Process control and monitoring of rinsing solutions, column thermostat for cooling and heating two iCol-e.g., in the semiconductor industry umns, an external column position in the room tempera- ture range and a bidirectional two-channel peristaltic The „ProfIC Vario 5 Anion“ is comprised of one 940 Pro-pump. fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent conductivity detector, one 800 Dosino, one 858 Profes-The instrument is equipped with the drive for the „MSM, sional Sample Processor and one IC equipment for MSM-HC and MSM-LC“ Metrohm Suppressor Module for MiPCT. chemical suppression and the „MCS“ Metrohm CO Sup- 2 pressor for CO suppression. The combination of the two 2 The 940 Professional IC Vario ONE/SeS/PP is equipped suppressors represents a sequential suppression and per-with the „ONE“ and „SeS/PP“ modules. It contains auto- mits very sensitive analyses, thanks to the extremely low matic sample and eluent degassing, „iPump“ IC high- background conductivity. The suppressor rotor is not pre- pressure pump with intelligent pump head, pulsation mounted. This gives the customer different options to absorber, six-way injection valve with Maltese cross drive, choose from and the suppressor rotor can be used in accordance with the respective application. With the 800 Dosino and the IC equipment for MiPCT, all of the parts required for Metrohm‘s intelligent preconcentration technique are on hand. The 858 Professional Sample Processor makes the sam- ples available. The transfer takes place with the 800 Dosino. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 5 Anion“ ProfIC Vario 5 Anion 156 Ion chromatography „ProfIC Vario 6 Anion“ – Professional IC Vario system with Inline Dilution and Inline Ultrafiltration The Professional IC Vario system with Metrohm Inline Technical Information Dilution, Metrohm Inline Ultrafiltration and con- Parts ductivity detection enables the fully automatic deter-1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP mination of anions that are present in very high concen- 1 x 2.850.9010 IC Conductivity Detector trations and that have matrices containing particles. 1 x 2.858.0020 858 Professional Sample Processor 1 x 2.741.0010 741 Magnetic Stirrer Typical areas of application: 1 x 2.800.0010 800 Dosino • Rinse, process and waste water 1 x 6.5330.120 IC equipment: Inline Dilution • Extractions and digestion solutions 1 x 6.5330.110 IC equipment: Inline Ultrafiltration • Food samples The „ProfIC Vario 6 Anion“ is comprised of one 940 Pro- column thermostat for cooling and heating two iCol- fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent umns, an external column position in the room tempera-conductivity detector, one 741 Magnetic Stirrer, one 800 ture range and a bidirectional two-channel peristaltic Dosino, one 858 Professional Sample Processor, an IC pump. The instrument is equipped with the drive for the equipment for Inline Dilution and an IC equipment for „MSM, MSM-HC and MSM-LC“ Metrohm Suppressor Inline Ultrafiltration. Module for chemical suppression and the „MCS“ Metrohm CO Suppressor for CO suppression. The com- 2 2 The 940 Professional IC Vario ONE/SeS/PP is equipped bination of the two suppressors represents a sequential with the „ONE“ and „SeS/PP“ modules. It contains auto-suppression and permits very sensitive analyses, thanks matic sample and eluent degassing, „iPump“ IC high-to the extremely low background conductivity. The sup- pressure pump with intelligent pump head, pulsation pressor rotor is not pre-mounted. This gives the customer absorber, six-way injection valve with Maltese cross drive, different options to choose from and the suppressor rotor can be used in accordance with the respective application. The „ProfIC Vario 6 Anion“ offers the option of automatic inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be diluted into the transfer tubing, doses it into the Liquid Handling Station and adds the required volume of dilution medium. All of the parts required are on hand with the IC equipment for Inline Dilution. The IC equipment for Inline Ultrafiltration contains all of the parts needed for integrating the subsequent Metrohm Inline Ultrafiltration in the system. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 6 Anion“ ProfIC Vario 6 Anion Ion chromatography 157 „ProfIC Vario 7 Anion“ – Professional IC Vario system with Inline Dilution and Inline Dialysis The Professional IC Vario system with Metrohm Inline Technical Information Dilution, Inline Dialysis and conductivity detec- Parts tion enables the fully automatic determination of anions 1 x 2.940.1510 940 Prof. IC Vario ONE/SeS/PP/Prep 1 that are present in high concentrations and in difficult 1 x 2.850.9010 IC Conductivity Detector matrices. 1 x 2.858.0020 858 Professional Sample Processor 1 x 2.741.0010 741 Magnetic Stirrer Typical areas of application: 1 x 2.800.0010 800 Dosino • Process, wash and waste water 1 x 6.5330.120 IC equipment: Inline Dilution • Samples containing oil 1 x 6.5330.100 IC equipment: Inline Dialysis • Inline Extraction for biodiesel analysis The „ProfIC Vario 7 Anion“ is comprised of one 940 Pro- Maltese cross drive, column thermostat for cooling and fessional IC Vario ONE/SeS/PP/Prep 1, one „iDetector“ heating two iColumns, an external column position in intelligent conductivity detector, one 741 Magnetic Stir-the room temperature range and a bidirectional two- rer, one 800 Dosino, one 858 Professional Sample Proc- channel peristaltic pump. The instrument is equipped essor, an IC equipment for Inline Dilution and an IC with the drive for the „MSM, MSM-HC and MSM-LC“ equipment for Inline Dialysis. Metrohm Suppressor Module for chemical suppression and the „MCS“ Metrohm CO Suppressor for CO sup- 2 2 The 940 Professional IC Vario ONE/SeS/PP/Prep 1 is pression. The combination of the two suppressors repre-equipped with the „ONE“, „SeS/PP“ and „Prep 1“ mod- sents a sequential suppression and permits very sensitive ules. It contains automatic sample and eluent degassing, analyses, thanks to the extremely low background con- „iPump“ IC high-pressure pump with intelligent pump ductivity. The suppressor rotor is not pre-mounted. This head, pulsation absorber, six-way injection valve with gives the customer different options to choose from and the suppressor rotor can be used in accordance with the respective application. The „ProfIC Vario 7 Anion“ offers the option of automatic inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be diluted into the transfer tubing, doses it into the Liquid Handling Station and adds the required volume of dilution medium. All of the parts required are on hand with the IC equipment for Inline Dilution. The IC equipment for Inline Dialysis contains all of the parts required for the subsequent Metrohm-patented „Inline Stopped Flow Dialysis“. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 7 Anion“ ProfIC Vario 7 Anion 158 Ion chromatography „ProfIC Vario 8 Anion“ – Professional IC Vario system with Inline Matrix Elimination The Professional IC Vario system with Metrohm Inline Technical Information Matrix Elimination and conductivity detection ena-Parts bles the determination of anions in difficult matrices. 1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP 1 x 2.850.9010 IC Conductivity Detector Typical areas of application: 1 x 2.858.0030 858 Professional Sample Processor • Trace analysis in polar solvents 1 x 6.1602.150 Bottle attachment / GL 45 - 3 × UNF • Quality controls in fuels, fuel mixtures and biofuels 1 x 6.1608.070 Eluent bottle / 2 L / GL 45 • Quality management of chemicals 1 x 6.1825.230 PEEK sample loop 10 µL The „ProfIC Vario 8 Anion“ is comprised of one 940 Pro- fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent conductivity detector and one 858 Professional Sample The instrument is equipped with the drive for the „MSM, Processor. MSM-HC and MSM-LC“ Metrohm Suppressor Module for chemical suppression and the „MCS“ Metrohm CO Sup- 2 The 940 Professional IC Vario ONE/SeS/PP is equipped pressor for CO suppression. The combination of the two 2 with the „ONE“ and „SeS/PP“ modules. It contains auto- suppressors represents a sequential suppression and per- matic sample and eluent degassing, „iPump“ IC high- mits very sensitive analyses, thanks to the extremely low pressure pump with intelligent pump head, pulsation background conductivity. The suppressor rotor is not pre-absorber, six-way injection valve with Maltese cross drive, mounted. This gives the customer different options to column thermostat for cooling and heating two iCol-choose from and the suppressor rotor can be used in umns, an external column position in the room tempera-accordance with the respective application. ture range and a bidirectional two-channel peristaltic pump. The injector and the peristaltic pump on the 858 Profes- sional Sample Processor and the additional accessory parts enable Inline Matrix Elimination. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. As a rule, only small volumes with a maximum of 1 mL sample are required for matrix elimination. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 8 Anion“ ProfIC Vario 8 Anion Ion chromatography 159 „ProfIC Vario 9 Anion“ – Professional IC Vario system with Metrohm‘s intelligent preconcentration technique and Inline Matrix Elimination (MiPCT-ME) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent inline preconcentration technique, Inline Parts Matrix Elimination and conductivity detection ena-1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP bles ultratrace analysis down to the lowest ppt range 1 x 2.850.9010 IC Conductivity Detector (ng/L) of anions in complex matrices. 1 x 2.858.0010 858 Professional Sample Processor 2 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.160 IC equipment: MiPCT-ME • Ultratrace analysis in samples from nuclear power plants and conventional power plants • Trace and ultratrace analysis in extraction agents and absorber, six-way injection valve with Maltese cross drive, organics column thermostat for cooling and heating two iCol- • Trace analysis in snow and ice umns, an external column position in the room tempera- ture range and a bidirectional two-channel peristaltic The „ProfIC Vario 9 Anion“ is comprised of one 940 Pro-pump. fessional IC Vario ONE/SeS/PP, one „iDetector“ intelligent conductivity detector, one 858 Professional Sample Proc-The instrument is equipped with the drive for the „MSM, essor, two 800 Dosinos and one IC equipment for MiPCT- MSM-HC and MSM-LC“ Metrohm Suppressor Module for ME. chemical suppression and the „MCS“ Metrohm CO Sup- 2 pressor for CO suppression. The combination of the two 2 The 940 Professional IC Vario ONE/SeS/PP is equipped suppressors represents a sequential suppression and per-with the „ONE“ and „SeS/PP“ modules. It contains auto- mits very sensitive analyses, thanks to the extremely low matic sample and eluent degassing, „iPump“ IC high- background conductivity. The suppressor rotor is not pre- pressure pump with intelligent pump head, pulsation mounted. This gives the customer different options to choose from and the suppressor rotor can be used in accordance with the respective application. The two 800 Dosinos and the IC equipment for MiPCT- ME enable preconcentration of the sample and subse- quent matrix elimination. Typical preconcentration volumes are 4 - 4,000 µL. The 858 Professional Sample Processor makes the sam- ples available. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 9 Anion“ ProfIC Vario 9 Anion 160 Ion chromatography „ProfIC Vario 10 Anion“ – Professional IC Vario system with Inline Neutralization The Professional IC Vario system with Metrohm Inline Technical Information Neutralization and conductivity detection enables Parts the determination of anions in extremely alkali, acidic or 1 x 2.940.1530 940 Prof. IC Vario ONE/SeS/PP/Prep 3 metal-polluted matrices. 1 x 2.850.9010 IC Conductivity Detector 1 x 6.2835.000 SPM Rotor A Typical areas of application: 1 x 2.858.0030 858 Professional Sample Processor • Trace analysis in bases and acids 1 x 6.1602.150 Bottle attachment / GL 45 - 3 × UNF • Starter substances from the electroplating industry 1 x 6.1608.070 Eluent bottle / 2 L / GL 45 • Contaminations in electroplating baths 1 x 6.1825.230 PEEK sample loop 10 µL The „ProfIC Vario 10 Anion“ is comprised of one 940 Professional IC Vario ONE/SeS/PP/Prep 3, one „iDetector“ the room temperature range and a bidirectional two-intelligent conductivity detector, one 858 Professional channel peristaltic pump. Sample Processor and additional accessory parts for In- line Neutralization. The instrument is equipped with the drive for the „MSM, MSM-HC and MSM-LC“ Metrohm Suppressor Module for The 940 Professional IC Vario ONE/SeS/PP/Prep 3 is chemical suppression and the „MCS“ Metrohm CO Sup-2 equipped with the „ONE“, „SeS/PP“ and „Prep 3“ mod- pressor for CO suppression. The combination of the two 2 ules. It contains automatic sample and eluent degassing, suppressors represents a sequential suppression and per- „iPump“ IC high-pressure pump with intelligent pump mits very sensitive analyses, thanks to the extremely low head, pulsation absorber, six-way injection valve with background conductivity. The suppressor rotor is not pre-Maltese cross drive, column thermostat for cooling and mounted. This gives the customer different options to heating two iColumns, an external column position in choose from and the suppressor rotor can be used in accordance with the respective application. In addition, the „SPM“ anion sample preparation module and a bidirectional two-channel peristaltic pump are located in the lower segment of the instrument („Prep 3“). Both of these components are used for Inline Neutralization and/or Inline Cation Removal. As a rule, only small volumes with a maximum of 1 mL sample are required for neutralization. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 10 Anion“ ProfIC Vario 10 Anion Ion chromatography 161 „ProfIC Vario 11 Anion“ – Professional IC Vario system with Inline Neutralization, intelligent precon- centration technique and Inline Matrix Elimination The Professional IC Vario system with Metrohm Inline Technical Information Neutralization, Metrohm‘s intelligent inline pre- Parts concentration technique, Inline Matrix Elimination 1 x 2.940.1530 940 Prof. IC Vario ONE/SeS/PP/Prep 3 and conductivity detection enables the analysis of 1 x 2.850.9010 IC Conductivity Detector anions in complex matrices from the ultratrace down to 1 x 2.858.0030 858 Professional Sample Processor the mg/L range. 1 x 2.800.0010 800 Dosino 1 x 6.2832.000 MSM-A Rotor (for SPM) Typical areas of application: 1 x 6.2842.020 Adapter sleeve for Suppressor Vario • Trace analysis in concentrated bases and acids 1 x 6.5330.140 IC equipment: MiPCT • Ultratrace analysis for nuclear power plants in matrices 1 x 6.1808.090 Thread adapter M8 outer / M6 inner such as lithium hydroxide/boric acid 1 x 6.1014.200 Metrosep I Trap 1 - 100/4.0 The „ProfIC Vario 11 Anion“ combines Inline Neutraliza- tion with MiPCT-ME. It is comprised of one 940 Profes- The instrument is equipped with the drive for the „MSM, sional IC Vario ONE/SeS/PP/Prep 3, one „iDetector“ MSM-HC and MSM-LC“ Metrohm Suppressor Module for intelligent conductivity detector, one 858 Professional chemical suppression and the „MCS“ Metrohm CO Sup-2 Sample Processor, one 800 Dosino and the IC equipment pressor for CO suppression. The combination of the two 2 for MiPCT. suppressors represents a sequential suppression and per- mits very sensitive analyses, thanks to the extremely low The 940 Professional IC Vario ONE/SeS/PP/Prep 3 is background conductivity. The suppressor rotor is not pre-equipped with the „ONE“, „SeS/PP“ and „Prep 3“ mod- mounted. This gives the customer different options to ules. It contains automatic sample and eluent degassing, choose from and the suppressor rotor can be used in „iPump“ IC high-pressure pump with intelligent pump accordance with the respective application. head, pulsation absorber, six-way injection valve with Maltese cross drive, column thermostat for cooling and In addition, the „SPM“ anion sample preparation module heating two iColumns, an external column position in and a bidirectional two-channel peristaltic pump are the room temperature range and a bidirectional two-located in the lower segment of the instrument („Prep channel peristaltic pump. 3“). Both components are used for the Metrohm Inline Neutralization. The package contains the 800 Dosino and accessories for Metrohm‘s intelligent preconcentration technique. To accomplish this purpose, the 800 Dosino pumps the precise sample quantity through the SPM module to the preconcentration column and then removes the matrix afterwards with ultrapure water. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 11 Anion“ ProfIC Vario 11 Anion 162 Ion chromatography „ProfIC Vario 12 Anion“ – Professional IC Vario sys- tem for online monitoring, Metrohm‘s intelligent pre- concentration technique and Inline Matrix Elimination The Professional IC Vario system with selection valve Technical Information and conductivity detection enables online determi-Parts nation with Metrohm‘s intelligent preconcentration 1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP technique and matrix elimination of anions from 1 x 2.850.9010 IC Conductivity Detector various sample flows. 1 x 2.942.0070 942 Extension Module Vario LQH 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.140 IC equipment: MiPCT • Continuous analysis of processes • Monitoring of drinking and surface water • Monitoring of cooling water umns, an external column position in the room tempera- ture range and a bidirectional two-channel peristaltic The „ProfIC Vario 12 Anion“ is comprised of one 940 pump. Professional IC Vario ONE/SeS/PP, one „iDetector“ intelli- gent conductivity detector, one 942 Extension Module The instrument is equipped with the drive for the „MSM, Vario LQH, one 800 Dosino and one IC equipment for MSM-HC and MSM-LC“ Metrohm Suppressor Module for MiPCT. chemical suppression and the „MCS“ Metrohm CO Sup- 2 pressor for CO suppression. The combination of the two 2 The 940 Professional IC Vario ONE/SeS/PP is equipped suppressors represents a sequential suppression and per-with the „ONE“ and „SeS/PP“ modules. It contains auto- mits very sensitive analyses, thanks to the extremely low matic sample and eluent degassing, „iPump“ IC high- background conductivity. The suppressor rotor is not pre- pressure pump with intelligent pump head, pulsation mounted. This gives the customer different options to absorber, six-way injection valve with Maltese cross drive, choose from and the suppressor rotor can be used in column thermostat for cooling and heating two iCol-accordance with the respective application. The 10-port valve contained in the 942 Extension Mod- ule LQH is used for selecting the various sample, standard and rinsing solutions. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net • Communication between MagIC Net and the process control software Ordering Information „ProfIC Vario 12 Anion“ ProfIC Vario 12 Anion Ion chromatography 163 „ProfIC Vario 14 Anion“ – Professional IC Vario system with Metrohm‘s intelligent Pick-up-Injection Technique (MiPuT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Pick-up Injection Technique (MiPuT) and con- Parts ductivity detection enables the determination of 1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP anions from the smallest of sample volumes. 1 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 2.800.0010 800 Dosino • For universal application for all types of samples when 1 x 6.5330.170 IC equipment: MiPuT only small sample quantities are available • Investigation of biochemical processes • Environmental sample extracts umns, an external column position in the room tempera- ture range and a bidirectional two-channel peristaltic The „ProfIC Vario 14 Anion“ is comprised of one 940 pump. Professional IC Vario ONE/SeS/PP, one „iDetector“ intelli- gent conductivity detector, one 858 Professional Sample The instrument is equipped with the drive for the „MSM, Processor, one 800 Dosino and one IC equipment for MSM-HC and MSM-LC“ Metrohm Suppressor Module for MiPuT. chemical suppression and the „MCS“ Metrohm CO Sup- 2 pressor for CO suppression. The combination of the two 2 The 940 Professional IC Vario ONE/SeS/PP is equipped suppressors represents a sequential suppression and per-with the „ONE“ and „SeS/PP“ modules. It contains auto- mits very sensitive analyses, thanks to the extremely low matic sample and eluent degassing, „iPump“ IC high- background conductivity. The suppressor rotor is not pre- pressure pump with intelligent pump head, pulsation mounted. This gives the customer different options to absorber, six-way injection valve with Maltese cross drive, choose from and the suppressor rotor can be used in column thermostat for cooling and heating two iCol-accordance with the respective application. The 800 Dosino and the IC equipment for MiPuT enable Metrohm‘s intel igent Pick-up Injection Technique. 2 - 50 µL of the samples can be removed and injected directly. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack (recommended 6.2041.480 Sample rack 159 x 2 mL + 3 x 300 mL) • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 14 Anion“ ProfIC Vario 14 Anion 164 Ion chromatography „ProfIC Vario 15 Anion“ – Professional IC Vario system with Metrohm‘s intelligent Partial Loop Injection Technique (MiPT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Partial Loop Injection Technique and con- Parts ductivity detection enables the fully automated deter-1 x 2.940.1500 940 Professional IC Vario ONE/SeS/PP mination of anions. „Partial Loop Injection“ enables the 1 x 2.850.9010 IC Conductivity Detector injection of various sample volumes. 1 x 2.858.0010 858 Professional Sample Processor 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.180 IC equipment: MiPT • For universal application for all types of samples • From trace analysis to waste water analysis • Great differences in concentration in a single sample column thermostat for cooling and heating two iCol-series umns, an external column position in the room tempera- ture range and a bidirectional two-channel peristaltic The „ProfIC Vario 15 Anion“ is comprised of one 940 pump. Professional IC Vario ONE/SeS/PP, one „iDetector“ intelli- gent conductivity detector, one 858 Professional Sample The instrument is equipped with the drive for the „MSM, Processor, one 800 Dosino and one IC equipment for MSM-HC and MSM-LC“ Metrohm Suppressor Module for MiPT. chemical suppression and the „MCS“ Metrohm CO Sup- 2 pressor for CO suppression. The combination of the two 2 The 940 Professional IC Vario ONE/SeS/PP is equipped suppressors represents a sequential suppression and per-with the „ONE“ and „SeS/PP“ modules. It contains auto- mits very sensitive analyses, thanks to the extremely low matic sample and eluent degassing, „iPump“ IC high- background conductivity. The suppressor rotor is not pre- pressure pump with intelligent pump head, pulsation mounted. This gives the customer different options to absorber, six-way injection valve with Maltese cross drive, choose from and the suppressor rotor can be used in accordance with the respective application. The 800 Dosino and the IC equipment for MiPT enable Metrohm‘s intelligent Partial Loop Injection Technique. 2 - 200 µL can be injected. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 15 Anion“ ProfIC Vario 15 Anion Ion chromatography 165 „ProfIC Vario 1 Amperometry“ – Professional IC Vario system for automated ion chromatography with amperometric detection The Professional IC Vario system with amperometric Technical Information detection enables the fully automatic determination of Parts sugar, oxidizable anions and additional oxidizable and 1 x 2.940.1100 940 Professional IC Vario ONE reducible components. 1 x 2.850.9110 IC Amperometric Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: • Universally applicable analysis of oxidizable or reducible components The 940 Professional IC Vario ONE is equipped with the • Routine analysis with large numbers of samples with- „ONE“ module. It contains automatic sample and eluent out additional sample preparation degassing, „iPump“ IC high-pressure pump with intelli- • Sugar analysis with pulsed amperometric detection gent pump head, pulsation absorber, six-way injection (PAD) valve with Maltese cross drive, column thermostat for • Trace analysis of cyanide and sulfide with direct cooling and heating two iColumns and an external amperometric detection (DC) column position in the room temperature range. • Analysis of additional oxidizable or reducible anions • Determination of organic components with different The amperometric detector can be operated in four dif-potential forms (flexIPAD) ferent modes (DC, PAD, flexIPAD and CV) and thus covers the entire application field of amperometric detection. The „ProfIC Vario 1 Amperometry“ is comprised of one 940 Professional IC Vario ONE, one „iDetector“ intelli-The 858 Professional Sample Processor takes care of the gent amperometric detector and one 858 Professional sample transfer. Numerous sample racks are available for Sample Processor. volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Amperometric measuring cell with the required electrodes • Sample rack • MagIC Net Ordering Information „ProfIC Vario 1 Amperometry“ ProfIC Vario 1 Amperometry 166 Ion chromatography „ProfIC Vario 1 UV/VIS“ – Professional IC Vario sys- tem for automated ion chromatography with UV/VIS detection The Professional IC Vario system with UV/VIS detection Technical Information enables the fully automated determination of anions, Parts cations and organic compounds with optical absorption. 1 x 2.940.1100 940 Professional IC Vario ONE 1 x 2.944.0010 944 Professional UV/VIS Detector Vario Typical areas of application: 1 x 2.858.0020 858 Professional Sample Processor • Universally applicable analysis for components that absorb UV or VIS light, respectively. • Routine analysis with large numbers of samples with- The 944 UV/VIS Detector Vario enables data acquisition out additional sample preparation at up to eight random wavelengths. In addition, the UV/ VIS spectrum can be determined in the chromatogram at The „ProfIC Vario 1 UV/VIS“ is comprised of one 940 any time. Professional IC Vario ONE, one 944 Professional UV/VIS Detector Vario and one 858 Professional Sample Proces- The 858 Professional Sample Processor takes care of the sor. sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The 940 Professional IC Vario ONE is equipped with the „ONE“ module. It contains automatic sample and eluent The following components must be ordered separately in degassing, „iPump“ IC high-pressure pump with intelli-accordance with the desired application: gent pump head, pulsation absorber, six-way injection • Separation column valve with Maltese cross drive, column thermostat for • Sample rack cooling and heating two iColumns and an external • MagIC Net column position in the room temperature range. Ordering Information „ProfIC Vario 1 UV/VIS“ ProfIC Vario 1 UV-VIS Ion chromatography 167 „ProfIC Vario 1 PCR-UV/VIS“ – Professional IC Vario system for automated ion chromatography with post- column derivatization and UV/VIS detection The Professional IC Vario system with post-column Technical Information derivatization and UV/VIS detection enables the Parts fully automated determination of anions, cations and 1 x 2.940.1110 940 Professional IC Vario ONE/Prep 1 additional components that can be converted using post- 1 x 2.943.0110 943 Professional Reactor Vario column derivatization into products with optical absorp- 1 x 2.944.0010 944 Professional UV/VIS Detector Vario tion. 1 x 2.858.0020 858 Professional Sample Processor 1 x 6.1608.030 Round glass bottle / 1,000 ml / GL 45 Typical areas of application: 1 x 6.1602.150 Bottle attachment / GL 45 - 3 × UNF • Universal analysis with post-column derivatization and 1 x 6.1803.030 PTFE capillary 0.5 mm i.d. / 3 m UV/VIS detection • Analysis with large numbers of samples without additional sample preparation with intelligent pump head, pulsation absorber, six-way • Trace analysis, e.g., of chromate, bromate, transition injection valve with Maltese cross drive, column thermo-metals, etc. stat for cooling and heating two iColumns and an exter- nal column position in the room temperature range. The „ProfIC Vario 1 PCR-UV/VIS“ is comprised of one 940 Professional IC Vario ONE/Prep 1, one 944 Professional In addition, a bidirectional two-channel peristaltic pump UV/VIS Detector Vario, one 943 Professional Reactor for conveying the post-column derivatization solution is Vario and one 858 Professional Sample Processor. located in the lower segment of the instrument („Prep 1“). The 940 Professional IC Vario ONE/Prep 1 is equipped with the „ONE“ module. It contains automatic sample Post-column derivatization is performed in the 943 Pro-and eluent degassing, „iPump“ IC high-pressure pump fessional Reactor Vario at temperatures up to 120 °C (or even up to 150 °C with the HT reactor plate). The 944 Professional UV/VIS Detector Vario enables data acquisition at up to eight random wavelengths. In addi- tion, the UV/VIS spectrum can be determined in the chromatogram at any time. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation column • Sample rack • MagIC Net Ordering Information „ProfIC Vario 1 PCR-UV/VIS“ ProfIC Vario 1 PCR-UV-VIS 168 Ion chromatography „ProfIC Vario 1 AnCat“ – Professional IC Vario system for automated ion chromatography The Professional IC Vario system with conductivity Technical Information detection and two analysis channels enables the Parts fully automatic determination of anions and cations, 1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP both in parallel and also completely independent from 2 x 2.850.9010 IC Conductivity Detector one another as a time-saving feature. 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: • Universal anion and cation analysis absorbers, two six-way injection valves, a column ther- • Routine analysis with large numbers of samples with- mostat for the cooling and heating of two „iColumn“ out additional sample preparation separation columns, an external column position in the room temperature range and a bidirectional two-channel The „ProfIC Vario 1 AnCat“ is comprised of one 940 peristaltic pump. Professional IC Vario TWO/SeS/PP, two „iDetector“ intel- ligent conductivity detectors and one 858 Professional The instrument is equipped with a drive for the „MSM, Sample Processor. MSM-HC and MSM-LC“ Metrohm Suppressor Module for chemical suppression and the „MCS“ Metrohm CO Sup- 2 The 940 Professional IC Vario TWO/SeS/PP is equipped pressor for CO suppression. The combination of the two 2 with two „ONE“ modules and one „SeS/PP“ module, thus suppressors represents a sequential suppression and per-resulting in an instrument with two analysis channels. mits very sensitive analyses, thanks to the extremely low background conductivity. The suppressor rotor is not pre- The instrument comprises automatic sample and eluent mounted. This gives the customer different options to degassing for both channels, two „iPump“ IC high-pres-choose from and the suppressor rotor can be used in sure pumps with intelligent pump heads and pulsation accordance with the respective application. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation columns • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 1 AnCat“ ProfIC Vario 1 AnCat Ion chromatography 169 „ProfIC Vario 2 AnCat“ – Professional IC Vario system with Inline Ultrafiltration The Professional IC Vario system with Metrohm Inline Technical Information Ultrafiltration and conductivity detection enables Parts the fully automatic determination of anions and cations. 1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP 2 x 2.850.9010 IC Conductivity Detector Typical areas of application: 1 x 2.858.0020 858 Professional Sample Processor • Samples with slight to medium-severe loads of parti- 1 x 6.5330.110 IC equipment: Inline Ultrafiltration cles, algae or bacteria • Drinking and surface water • Process and waste water mostat for the cooling and heating of two „iColumn“ separation columns, an external column position in the The „ProfIC Vario 2 AnCat“ is comprised of one 940 room temperature range and a bidirectional two-channel Professional IC Vario TWO/SeS/PP, two intelligent con-peristaltic pump. ductivity detectors, one 858 Professional Sample Proces- sor and an IC equipment for Inline Ultrafiltration. It is equipped with a drive for the „MSM, MSM-HC and MSM-LC“ Metrohm Suppressor Module for chemical The 940 Professional IC Vario TWO/SeS/PP is equipped suppression and the „MCS“ Metrohm CO Suppressor for 2 with two „ONE“ modules and one „SeS/PP“ module, thus CO suppression. The combination of the two suppressors 2 resulting in an instrument with two analysis channels. represents a sequential suppression and permits very sensitive analyses, thanks to the extremely low back-The instrument comprises automatic sample and eluent ground conductivity. The suppressor rotor is not pre-degassing for both channels, two „iPump“ IC high-pres- mounted. This gives the customer different options to sure pumps with intelligent pump heads and pulsation choose from and the suppressor rotor can be used in absorbers, two six-way injection valves, a column ther-accordance with the respective application. The IC equipment for Inline Ultrafiltration contains all of the parts needed for integrating Metrohm Inline Ultrafiltration in the system. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL for the 858 Professional Sample Processor. A minimum of 7 - 10 mL of sample is required for the Inline Ultrafiltration. The following components must be ordered separately in accordance with the desired application: • Separation columns • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 2 AnCat“ ProfIC Vario 2 AnCat 170 Ion chromatography „ProfIC Vario 4 AnCat“ – Professional IC Vario system with Inline Dilution The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Inline Dilution and conductivity detection Parts enables the fully automated determination of anions and 1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP cations in concentrated solutions. 2 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 2.741.0010 741 Magnetic Stirrer • Samples with high ion concentration 1 x 2.800.0010 800 Dosino • Samples from all industries 1 x 6.5330.120 IC equipment: Inline Dilution The „ProfIC Vario 4 AnCat“ is comprised of one 940 Professional IC Vario TWO/SeS/PP, two „iDetector“ intel- perature range and a bidirectional two-channel peristaltic ligent conductivity detectors, one 741 Magnetic Stirrer, pump. one 800 Dosino and one IC equipment for Inline Dilution. The instrument is equipped with a drive for the „MSM, MSM-HC and MSM-LC“ Metrohm Suppressor Module for The 940 Professional IC Vario TWO/SeS/PP is equipped chemical suppression and the „MCS“ Metrohm CO Sup-2 with two „ONE“ modules and one „SeS/PP“ module, thus pressor for CO suppression. The combination of the two 2 resulting in an instrument with two analysis channels. It suppressors represents a sequential suppression and per-comprises automatic sample and eluent degassing for mits very sensitive analyses, thanks to the extremely low both channels, two „iPump“ IC high-pressure pumps background conductivity. The suppressor rotor is not pre-with intelligent pump heads and pulsation absorbers, mounted. This gives the customer different options to two six-way injection valves, a column thermostat for the choose from and the suppressor rotor can be used in cooling and heating of two „iColumn“ separation accordance with the respective application. columns, an external column position in the room tem- The „ProfIC Vario 4 AnCat“ offers the option of automated inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be diluted into the transfer tubing, doses it into the Liquid Handling Station and adds the required volume of dilution medium. All of the parts required are on hand with the IC equipment for Inline Dilution. The 858 Professional Sample Processor takes care of the sample transfer. Numerous sample racks are available for volumes in the range of 0.5 - 500 mL. The following components must be ordered separately in accordance with the desired application: • Separation columns • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 4 AnCat“ ProfIC Vario 4 AnCat Ion chromatography 171 „ProfIC Vario 5 AnCat“ – Professional IC Vario system with Metrohm‘s intelligent preconcentration technique (MiPCT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent inline sample preconcentration and conduc- Parts tivity detection enables the fully automatic determina-1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP tion of anions and cations in solutions with low ion 2 x 2.850.9010 IC Conductivity Detector concentration. 1 x 2.815.0130 815 USB Sample Processor (2T/0P) 2 x 2.800.0010 800 Dosino Typical areas of application: 2 x 6.5330.140 IC equipment: MiPCT • Numerous applications, ranging from ultrapure water and additional parts for the Sample Processor analysis to drinking water analysis • Analyses of different samples from power plants • Process control and monitoring of rinsing solutions, The instrument comprises automatic sample and eluent e.g., in the semiconductor industry degassing for both channels, two „iPump“ IC high-pres- • Trace analysis in snow and ice sure pumps with intelligent pump heads and pulsation absorbers, two six-way injection valves, a column ther-The „ProfIC Vario 5 AnCat“ is comprised of one 940 mostat for the cooling and heating of two „iColumn“ Professional IC Vario TWO/SeS/PP, two „iDetector“ intel- separation columns, an external column position in the ligent conductivity detectors, two 800 Dosinos, one 815 room temperature range and a bidirectional two-channel Robotic USB Sample Processor XL (2T/0P) with two work-peristaltic pump. The instrument is equipped with a drive stations and two IC equipments for MiPCT. for the „MSM, MSM-HC and MSM-LC“ Metrohm Sup- pressor Module for chemical suppression and the „MCS“ The 940 Professional IC Vario TWO/SeS/PP is equipped Metrohm CO Suppressor for CO suppression. The com-2 2 with two „ONE“ modules and one „SeS/PP“ module, thus bination of the two suppressors represents a sequential resulting in an instrument with two analysis channels. suppression and permits very sensitive analyses, thanks to the extremely low background conductivity. The suppressor rotor is not pre-mounted. With the two 800 Dosinos and the two IC equipments for MiPCT, all of the parts required for Metrohm‘s intelligent preconcentration technique in two-channel oper- ation are on hand. The two towers of the 814 USB Sample Processor (2T/0P) enable carry-over-free sampling for anion and cation determination through two independent sample needles. The following components must be ordered separately in accordance with the desired application: • Separation columns • Preconcentration columns • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 5 AnCat“ ProfIC Vario 5 AnCat 172 Ion chromatography „ProfIC Vario 6 AnCat“ – Professional IC Vario system with Inline Dilution and Inline Ultrafiltration The Professional IC Vario system with Metrohm Inline Technical Information Dilution, Metrohm Inline Ultrafiltration and con- Parts ductivity detection enables the fully automated deter-1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP mination of anions and cations that are present in very 2 x 2.850.9010 IC Conductivity Detector high concentrations and that have matrices containing 1 x 2.858.0020 858 Professional Sample Processor particles. 1 x 2.741.0010 741 Magnetic Stirrer 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.120 IC equipment: Inline Dilution • Rinse, process and waste water 1 x 6.5330.110 IC equipment: Inline Ultrafiltration • Extractions and digestion solutions • Food samples both channels, two „iPump“ IC high-pressure pumps The „ProfIC Vario 6 AnCat“ is comprised of one 940 with intelligent pump heads and pulsation absorbers, Professional IC Vario TWO/SeS/PP, two „iDetector“ intel-two six-way injection valves, a column thermostat for the ligent conductivity detectors, one 741 Magnetic Stirrer, cooling and heating of two „iColumn“ separation one 800 Dosino, one 858 Professional Sample Processor, columns, an external column position in the room tem-an IC equipment for Inline Dilution and an IC equipment perature range and a bidirectional two-channel peristaltic for Inline Ultrafiltration. pump. The instrument is equipped with a drive for the „MSM, MSM-HC and MSM-LC“ Metrohm Suppressor The 940 Professional IC Vario TWO/SeS/PP is equipped Module for chemical suppression and the „MCS“ with two „ONE“ modules and one „SeS/PP“ module, thus Metrohm CO Suppressor for CO suppression. The com-2 2 resulting in an instrument with two analysis channels. It bination of the two suppressors represents a sequential comprises automatic sample and eluent degassing for suppression and permits very sensitive analyses, thanks to the extremely low background conductivity. The suppressor rotor is not pre-mounted. The „ProfIC Vario 6 AnCat“ offers the option of automated inline dilution of every sample. This takes place at an external position on the 858 Professional Sample Processor. The 800 Dosino aspirates the volume to be diluted into the transfer tubing, doses it into the Liquid Handling Station and adds the required volume of dilution medium. With the IC equipment for Inline Dilution and for Inline Ultrafiltration, all of the parts needed to integrate Inline Dilution and Inline Ultrafiltration in the system are on hand. The following components must be ordered separately in accordance with the desired application: • Separation columns • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 6 AnCat“ ProfIC Vario 6 AnCat Ion chromatography 173 „ProfIC Vario 9 AnCat“ – Professional IC Vario system with Metrohm‘s intelligent preconcentration technique and Inline Matrix Elimination (MiPCT-ME) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent inline preconcentration technique, Inline Parts Matrix Elimination and conductivity detection ena-1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP bles ultratrace analysis down to the lowest ppt range 2 x 2.850.9010 IC Conductivity Detector (ng/L) of anions and cations in complex matrices. 1 x 2.815.0130 815 USB Sample Processor (2T/0P) 3 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.160 IC equipment: MiPCT-ME • Ultratrace analysis in samples from nuclear power 1 x 6.5330.140 IC equipment: MiPCT plants and conventional power plants 1 x 6.1014.200 Metrosep I Trap 1 - 100/4.0 • Trace and ultratrace analysis in extraction agents and and additional parts for the Sample Processor organics The „ProfIC Vario 9 AnCat“ is comprised of one 940 both channels, two „iPump“ IC high-pressure pumps Professional IC Vario TWO/SeS/PP, two „iDetector“ intel-with intelligent pump heads and pulsation absorbers, ligent conductivity detectors, three 800 Dosinos, one two six-way injection valves, a column thermostat for the 815 Robotic USB Sample Processor XL (2T/0P) with two cooling and heating of two „iColumn“ separation workstations and one IC equipment each for MiPCT and columns, an external column position in the room tem-MiPCT-ME. perature range and a bidirectional two-channel peristaltic pump. The 940 Professional IC Vario TWO/SeS/PP is equipped The instrument is equipped with a drive for the „MSM, with two „ONE“ modules and one „SeS/PP“ module, thus MSM-HC and MSM-LC“ Metrohm Suppressor Module for resulting in an instrument with two analysis channels. It chemical suppression and the „MCS“ Metrohm CO Sup-2 comprises automatic sample and eluent degassing for pressor for CO suppression. The combination of the two 2 suppressors represents a sequential suppression and per- mits very sensitive analyses, thanks to the extremely low background conductivity. The suppressor rotor is not pre- mounted. One 800 Dosino each per sample channel and the IC equipments for MiPCT or MiPCT-ME, respectively, enable the preconcentration of the sample and the subsequent matrix elimination. Typical preconcentration volumes are 4 - 4,000 µL. The two towers of the 815 Robotic USB Sample Processor XL (2T/0P) enable carry-over-free sam- pling for anion and cation determination through two independent sample needles. The following components must be ordered separately in accordance with the desired application: • Separation column • Preconcentration column • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 9 AnCat“ ProfIC Vario 9 AnCat 174 Ion chromatography „ProfIC Vario 14 AnCat“ – Professional IC Vario system with Metrohm‘s intelligent Pick-up Injection Technique (MiPuT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Pick-up Injection Technique (MiPuT) and con- Parts ductivity detection enables the determination of 1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP anions and cations from the smallest of sample volumes. 2 x 2.850.9010 IC Conductivity Detector 1 x 2.858.0020 858 Professional Sample Processor Typical areas of application: 1 x 2.800.0010 800 Dosino • For universal application for all types of samples when 1 x 6.5330.170 IC equipment: MiPuT only small sample quantities are available 1 x 6.1825.290 PEEK sample loop 250 µL • Investigation of biochemical processes • Environmental sample extracts two six-way injection valves, a column thermostat for the The „ProfIC Vario 14 AnCat“ is comprised of one 940 cooling and heating of two „iColumn“ separation Professional IC Vario TWO/SeS/PP, two „iDetector“ intel-columns, an external column position in the room tem- ligent conductivity detectors, one 858 Professional Sam- perature range and a bidirectional two-channel peristaltic ple Processor, one 800 Dosino and one IC equipment for pump. MiPuT. The instrument is equipped with a drive for the „MSM, The 940 Professional IC Vario TWO/SeS/PP is equipped MSM-HC and MSM-LC“ Metrohm Suppressor Module for with two „ONE“ modules and one „SeS/PP“ module, thus chemical suppression and the „MCS“ Metrohm CO Sup-2 resulting in an instrument with two analysis channels. It pressor for CO suppression. The combination of the two 2 comprises automatic sample and eluent degassing for suppressors represents a sequential suppression and per-both channels, two „iPump“ IC high-pressure pumps mits very sensitive analyses, thanks to the extremely low with intelligent pump heads and pulsation absorbers, background conductivity. The suppressor rotor is not pre-mounted. This gives the customer different options to choose from and the suppressor rotor can be used in accordance with the respective application. The 800 Dosino and the IC equipment for MiPuT enable Metrohm‘s intelligent Pick-up Injection Technique for both analysis channels. 2 - 50 µL of each of the samples can be removed and injected directly. The following components must be ordered separately in accordance with the desired application: • Separation columns • Sample rack (recommended 6.2041.480 Sample rack 159 x 2 mL + 3 x 300 mL) • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 14 AnCat“ ProfIC Vario 14 AnCat Ion chromatography 175 „ProfIC Vario 15 AnCat“ – Professional IC Vario system with Metrohm‘s intelligent Partial Loop Injection Technique (MiPT) The Professional IC Vario system with Metrohm‘s intel- Technical Information ligent Partial Loop Injection Technique and con- Parts ductivity detection enables the fully automatic deter-1 x 2.940.2500 940 Professional IC Vario TWO/SeS/PP mination of anions and cations. „Partial Loop Injection“ 2 x 2.850.9010 IC Conductivity Detector enables the injection of various sample volumes. 1 x 2.858.0010 858 Professional Sample Processor 1 x 2.800.0010 800 Dosino Typical areas of application: 1 x 6.5330.180 IC equipment: MiPT • For universal application for all types of samples 1 x 6.1825.290 PEEK sample loop 250 µL • From trace analysis to waste water analysis 1 x 6.1841.000 PEEK transfer capillary 2 mL, 5 m • Great differences in concentration in a single sample 1 x 6.2744.080 M6 thread / UNF 10/32 coupling series 1 x 6.2744.290 T connector 3 × UNF 10/32 with holder The „ProfIC Vario 15 AnCat“ is comprised of one 940 Professional IC Vario TWO/SeS/PP, two „iDetector“ intel- with intelligent pump heads and pulsation absorbers, ligent conductivity detectors, one 858 Professional Sam-two six-way injection valves, a column thermostat for the ple Processor, one 800 Dosino and the IC equipment for cooling and heating of two „iColumn“ separation MiPT. columns, an external column position in the room tem- perature range and a bidirectional two-channel peristaltic The 940 Professional IC Vario TWO/SeS/PP is equipped pump. with two „ONE“ modules and one „SeS/PP“ module, thus resulting in an instrument with two analysis channels. It The instrument is equipped with a drive for the „MSM, comprises automatic sample and eluent degassing for MSM-HC and MSM-LC“ Metrohm Suppressor Module for both channels, two „iPump“ IC high-pressure pumps chemical suppression and the „MCS“ Metrohm CO Sup-2 pressor for CO suppression. The combination of the two 2 suppressors represents a sequential suppression and per- mits very sensitive analyses, thanks to the extremely low background conductivity. The suppressor rotor is not pre- mounted. This gives the customer different options to choose from and the suppressor rotor can be used in accordance with the respective application. The 800 Dosino and the IC equipment for MiPT enable Metrohm‘s intelligent Partial Loop Injection Technique. 2 - 200 µL can be injected. The following components must be ordered separately in accordance with the desired application: • Separation columns • Sample rack • Suppressor rotor • MagIC Net Ordering Information „ProfIC Vario 15 AnCat“ ProfIC Vario 15 AnCat 176 Ion chromatography Professional IC Vario – Instruments 940 Professional IC Vario instruments – Introduction 940 Professional IC Vario – a system of innovative and intelligent components that are optimally coordinated with one another! Configuration: The configuration of the system is as sim- ple as possible, as the components log in automatically and make all relevant information available to the MagIC Net software. Monitoring: The system monitors and optimizes all func- tions and documents them in accordance with FDA requirements upon request. Optimum operation of the 940 Professional IC Vario and the results are both moni- tored. If a parameter lies outside of the specified range, then the user will be informed via e-mail or SMS. Inline Sample Preparation: The path from the sample to the precise result has become faster, as now even com- plex sample preparation steps are carried out inline and automatically. The system optimizes the sample precon- centration or the sample dilution automatical y if required. Free detector selection: The detection type can be select- ed to suit. That is the reason why no detector is included in the scope of delivery of the Professional IC Vario instruments. • Intelligent pump: iPump • Intelligent detector: iDetector • Intelligent column: iColumn • Intelligent cells: iCell • Intelligent reactors: iReactor • Intelligent Liquid Handling with Dosinos • Extension Module Ion chromatography 177 940 Professional IC Vario – Overview Suppression Sample preparation Gradient ONE Chemical Sequential MCS Prep 1 Prep 2 Prep 3 HPG LPG iPump + PP + PP + MSM MCS PP PP Inj. Inj. SPM 2.940.1100 Professional IC Vario ONE yes − − − − − − − − Professional IC Vario 2.940.1110 yes − − − yes − − − − ONE/Prep 1 Professional IC Vario 2.940.1120 yes − − − − yes − − − ONE/Prep 2 Professional IC Vario 2.940.1140 yes − − − − − − yes − ONE/HPG Professional IC Vario 2.940.1150 yes − − − − − − − yes ONE/LPG Professional IC Vario 2.940.1200 yes yes − − − − − − − ONE/ChS Professional IC Vario 2.940.1240 yes yes − − − − − − − ONE/ChS/HPG Professional IC Vario 2.940.1250 yes yes − − − − − − − ONE/ChS/LPG Professional IC Vario 2.940.1300 yes yes − yes − − − − − ONE/ChS/PP Professional IC Vario 2.940.1340 yes yes − yes − − − yes − ONE/ChS/PP/HPG Professional IC Vario 2.940.1350 yes yes − yes − − − − yes ONE/ChS/PP/LPG 2.940.1400 Professional IC Vario SeS yes yes yes − − − − − − Professional IC Vario 2.940.1410 yes yes yes − yes − − − − SeS/Prep 1 Professional IC Vario 2.940.1420 yes yes yes − − yes − − − SeS/Prep 2 Professional IC Vario 2.940.1430 yes yes yes − − − yes − − SeS/Prep 3 2.940.1440 Professional IC Vario SeS/HPG yes yes yes − − − − yes - 2.940.1450 Professional IC Vario SeS/LPG yes yes yes − − − − − yes 2.940.1500 Professional IC Vario SeS/PP yes yes yes yes − − − − − Professional IC Vario 2.940.1510 yes yes yes yes yes − − − − SeS/PP/Prep 1 Professional IC Vario 2.940.1520 yes yes yes yes − yes − − − SeS/PP/Prep 2 Professional IC Vario 2.940.1530 yes yes yes yes − − yes − − SeS/PP/Prep 3 Professional IC Vario 2.940.1540 yes yes yes yes − − − yes − SeS/PP/HPG Professional IC Vario 2.940.1550 yes yes yes yes − − − − yes SeS/PP/LPG 2.940.2100 Professional IC Vario TWO yes (2x) − − − − − − − − Professional IC Vario 2.940.2200 yes (2x) yes − − − − − − − TWO/ChS Professional IC Vario 2.940.2300 yes (2x) yes − yes − − − − − TWO/ChS/PP Professional IC Vario 2.940.2400 yes (2x) yes yes − − − − − − TWO/SeS Professional IC Vario 2.940.2500 yes (2x) yes yes yes − − − − − TWO/SeS/PP 178 Ion chromatography Professional IC Vario instruments 940 Professional IC Vario ONE (2.940.1100) The 940 Professional IC Vario ONE is the intelligent IC instrument for applications without suppression. The instrument can be used with any separation and detec-940 tion Pr methods.ofessional IC Vario ONE 940 Professional IC Vario ONE/Prep 1 (2.940.1110) The 940 Professional IC Vario ONE/Prep 1 is the intelligent IC instrument without suppression in combination with Metrohm Inline Sample Preparation, e.g., In- 940 line Ultr Professional afiltration or Inline IC Dialysis. V The ario instrument can be used with any separation and detection methods. ONE/Prep 1 940 Professional IC Vario ONE/Prep 2 (2.940.1120) The 940 Professional IC Vario ONE/Prep 2 is the intelligent IC instrument without suppression in combination with Metrohm Inline Sample Preparation, e.g., Inline 940 Matrix Professional Elimination or Inline C IC alibr V ation ario . The instru- ment can be used with any separation and detection ONE/Pr methods. ep 2 940 Professional IC Vario ONE/HPG (2.940.1140) The 940 Professional IC Vario ONE/HPG is the intelligent IC instrument without suppression with binary high- pressure gradient. It can be extended with the 942 940 Pr Extension ofessional Modules to up to a IC V quaternary grario adient sys- tem. The instrument can be used with any separation ONE/HPG and detection methods. Ion chromatography 179 940 Professional IC Vario ONE/LPG (2.940.1150) The 940 Professional IC Vario ONE/LPG is the intelligent IC instrument without suppression with low-pressure gradient. The instrument can be used with any separa-940 tion and Professional detection methods. IC Vario ONE/LPG 940 Professional IC Vario ONE/ChS (2.940.1200) The 940 Professional IC Vario ONE/ChS is the intelligent IC instrument with chemical suppression. An 800 Dosino can be used for the regeneration of the suppres- 940 sor. The Professional instrument can be used IC with any Vario separation and detection methods. ONE/ChS 940 Professional IC Vario ONE/ChS/HPG (2.940.1240) The 940 Professional IC Vario ONE/ChS/HPG is the intel- ligent IC instrument with chemical suppression and 940 binary Professional high-pressure gradient. IC It V can ario be extended with the 942 Extension Modules to up to a quaternary ONE/ChS/HPG gradient system. An 800 Dosino can be used for the regeneration of the suppressor. The instrument can be used with any separation and detection methods. 940 Professional IC Vario ONE/ChS/LPG (2.940.1250) The 940 Professional IC Vario ONE/ChS/LPG is the intelli- gent IC instrument with chemical suppression and low-pressure gradient. An 800 Dosino can be used 940 for the r Professional egeneration of the suppr IC essor. V The ario instrument can be used with any separation and detection methods. ONE/ChS/LPG 180 Ion chromatography 940 Professional IC Vario ONE/ChS/PP (2.940.1300) The 940 Professional IC Vario ONE/ChS/PP is the intelli- gent IC instrument with chemical suppression and a peristaltic pump for suppressor regeneration. The in-940 strument Pr can ofessional be used with any separIC ation Vario and detection methods. ONE/ChS/PP 940 Professional IC Vario ONE/ChS/PP/HPG (2.940.1340) The 940 Professional IC Vario ONE/ChS/PP/HPG is the intelligent IC instrument with chemical suppression, a 940 peristalt Pr ic ofessional pump for suppressor IC regeV ne ario ration and binary high-pressure gradient. It can be extended ONE/ChS/PP/HPG with the 942 Extension Modules to up to a quaternary gradient system. The instrument can be used with any separation and detection methods. 940 Professional IC Vario ONE/ChS/PP/LPG (2.940.1350) The 940 Professional IC Vario ONE/ChS/PP/LPG is the intelligent IC instrument with chemical suppression, a 940 Pr peristaltic ofessional pump for suppressor r IC egener Vario ation and low- pressure gradient. The instrument can be used with ONE/ChS/PP/LPG any separation and detection methods. 940 Professional IC Vario ONE/SeS (2.940.1400) The 940 Professional IC Vario ONE/SeS is the intelligent IC instrument for applications with sequential sup- pression. An 800 Dosino can be used for the regenera-940 tion of Pr the ofessional suppressor. The IC instrument V can ario be used with any separation and detection methods. ONE/SeS Ion chromatography 181 940 Professional IC Vario ONE/SeS/Prep 1 (2.940.1410) The 940 Professional IC Vario ONE/SeS/Prep 1 is the intel- ligent IC instrument with sequential suppression in 940 Pr combination ofessional with Metrohm Inline IC V Sample ario Preparation, e.g., Inline Ultrafiltration or Inline Dialysis. An 800 ONE/SeS/Pr Dosino can be used for ep the r 1 egeneration of the suppres- sor. The instrument can be used with any separation and detection methods. 940 Professional IC Vario ONE/SeS/Prep 2 (2.940.1420) The 940 Professional IC Vario ONE/SeS/Prep 2 is the intel- ligent IC instrument with sequential suppression in 940 Pr combination ofessional with Metrohm Inline IC V Sample ario Preparation, e.g., Inline Matrix Elimination or Inline Calibration. ONE/SeS/Pr An 800 Dosino can be ep used 2 for the regeneration of the suppressor. The instrument can be used with any separa- tion and detection methods. 940 Professional IC Vario ONE/SeS/Prep 3 (2.940.1430) The 940 Professional IC Vario ONE/SeS/Prep 3 is the intel- ligent IC instrument with sequential suppression in 940 Pr combination ofessional with Metrohm Inline IC V Sample ario Preparation, e.g., Inline Neutralization or Inline Cation Removal. ONE/SeS/Pr An 800 Dosino can be ep used 3 for the regeneration of the suppressor. The instrument can be used with any separa- tion and detection methods. 940 Professional IC Vario ONE/SeS/HPG (2.940.1440) The 940 Professional IC Vario ONE/SeS/HPG is the intelli- gent IC instrument with sequential suppression and binary high-pressure gradient. It can be extended 940 with the Pr 942 ofessional Extension Modules to IC up V to a ario quaternary gradient system. An 800 Dosino can be used for the ONE/SeS/HPG regeneration of the suppressor. The instrument can be used with any separation and detection methods. 182 Ion chromatography 940 Professional IC Vario ONE/SeS/LPG (2.940.1450) The 940 Professional IC Vario ONE/SeS/LPG is the intelli- gent IC instrument with sequential suppression and low-pressure gradient. An 800 Dosino can be used 940 for the r Professional egeneration of the suppr IC essor. V The ario instrument can be used with any separation and detection methods. ONE/SeS/LPG 940 Professional IC Vario ONE/SeS/PP (2.940.1500) The 940 Professional IC Vario ONE/SeS/PP is the intelligent IC instrument with sequential suppression and a peristaltic pump for suppressor regeneration. The in-940 strument Pr can ofessional be used with any separIC ation Vario and detection methods. ONE/SeS/PP 940 Professional IC Vario ONE/SeS/PP/Prep 1 (2.940.1510) The 940 Professional IC Vario ONE/SeS/PP/Prep 1 is the intelligent IC instrument with sequential suppression 940 and a Professional peristaltic pump for suppr IC essor r Vario egeneration in combination with Metrohm Inline Sample Preparation, ONE/SeS/PP/Pr e.g., Inline Ultrafiltration ep or 1 Inline Dialysis. The in- strument can be used with any separation and detection methods. 940 Professional IC Vario ONE/SeS/PP/Prep 2 (2.940.1520) The 940 Professional IC Vario ONE/SeS/PP/Prep 2 is the intelligent IC instrument with sequential suppression 940 and a Professional peristaltic pump for suppr IC essor r Vario egeneration in combination with Metrohm Inline Sample Preparation, ONE/SeS/PP/Pr e.g., Inline Matrix ep Elimination or 2 Inline Calibration. The instrument can be used with any separation and detection methods. Ion chromatography 183 940 Professional IC Vario ONE/SeS/PP/Prep 3 (2.940.1530) The 940 Professional IC Vario ONE/SeS/PP/Prep 3 is the intelligent IC instrument with sequential suppression 940 with a Professional peristaltic pump for suppr IC essor r Vario egeneration in combination with Metrohm Inline Sample Preparation, ONE/SeS/PP/Pr e.g., Inline Neutralization ep or 3 Inline Cation Removal. The instrument can be used with any separation and detection methods. 940 Professional IC Vario ONE/SeS/PP/HPG (2.940.1540) The 940 Professional IC Vario ONE/SeS/PP/HPG is the intelligent IC instrument with sequential suppression, 940 a Professional peristaltic pump for suppr IC essor r Vario egeneration and binary high-pressure gradient. It can be extended ONE/SeS/PP/HPG with the 942 Extension Modules to up to a quaternary gradient system. The instrument can be used with any separation and detection methods. 940 Professional IC Vario ONE/SeS/PP/LPG (2.940.1550) The 940 Professional IC Vario ONE/SeS/PP/LPG is the intelligent IC instrument with sequential suppression, 940 a Professional peristaltic pump for suppr IC essor r Vario egeneration and low-pressure gradient. The instrument can be used ONE/SeS/PP/LPG with any separation and detection methods. 940 Professional IC Vario TWO (2.940.2100) The 940 Professional IC Vario TWO is the intelligent two- channel IC instrument without suppression. The instrument can be used with any separation and detection 940 methods. Professional IC Vario TWO 184 Ion chromatography 940 Professional IC Vario TWO/ChS (2.940.2200) The 940 Professional IC Vario TWO/ChS is the intelligent two-channel IC instrument with a chemical suppres- sor. An 800 Dosino can be used for the regeneration of 940 the Pr suppr ofessional essor. The instrument IC can be Vario used with any separation and detection methods. TWO/ChS 940 Professional IC Vario TWO/ChS/PP (2.940.2300) The 940 Professional IC Vario TWO/ChS/PP is the intelli- gent two-channel IC instrument with a chemical suppressor and a peristaltic pump for suppressor 940 regener Pr ation. ofessional The instrument can be IC used Vario with any sepa- ration and detection methods. TWO/ChS/PP 940 Professional IC Vario TWO/SeS (2.940.2400) The 940 Professional IC Vario TWO/SeS is the intelligent two-channel IC instrument with sequential suppres- sion (one channel). An 800 Dosino can be used for the 940 regener Pr ation ofessional of the suppressor. IC The Vario instrument can be used with any separation and detection methods. TWO/SeS 940 Professional IC Vario TWO/SeS/PP (2.940.2500) The 940 Professional IC Vario TWO/SeS/PP is the intelli- gent two-channel IC instrument with sequential suppression (one channel) and a peristaltic pump for 940 suppr Pr essor r ofessional egeneration. The IC instrument Vario can be used with any separation and detection methods. TWO/SeS/PP Ion chromatography 185 Professional IC Vario – Detectors IC Conductivity Detector (2.850.9010) Compact and intelligent high performance conductivity detector for intelligent IC instruments. Outstanding temperature stability, the complete signal processing within IC the Conductivity protected detector block and Detector the latest generation of DSP – Digital Signal Processing – guarantee the highest precision of the measurement. No change of measuring ranges (not even automatic ones) is required, due to the dynamic working range. IC Amperometric Detector (2.850.9110) Compact and intelligent amperometric detector for intel- ligent IC instruments. Outstanding selectivity due to the four measuring modes: DC, PAD, flexIPAD and CV, as well IC as Amper the excellent ometric signal/noise ratio Detector and the very fast stabi- lization of the measuring signal guarantee the highest in measurement precision. 944 Professional UV/VIS Detector Vario (2.944.0010) The 944 Professional UV/VIS Detector Vario is the intelligent UV/VIS detector from Metrohm. It permits a secure and reliable quantification of substances active in the 944 ultr Pr aviolet or ofessional visible range. UV/VIS Detection takes place via a Diode Array. Detector Vario 945 Professional Detector Vario – Conductivity (2.945.0010) Intelligent stand-alone detector equipped with a high-performance IC Conductivity Detector. For use with 945 Pr intelligent IC ofessional instruments or as Detector independent conductivity detector. Vario – Conductivity 186 Ion chromatography 945 Professional Detector Vario – Amperometry (2.945.0020) Intelligent stand-alone detector equipped with the IC Amperometric Detector. Outstanding selectivity due to 945 the four Professional measuring modes: DC, P Detector AD, flexIPAD, CV. The excellent signal/noise ratio and the very fast start-up Vario guarantee – the Amper highest in ometry measurement precision. For use with intelligent IC instruments or as independent detec- tor. 945 Professional Detector Vario – Conductivity & Amperometry (2.945.0030) Intelligent stand-alone detector equipped with the high performance IC Conductivity Detector and the IC 945 Amper Professional ometric Detector, with the Detector four measuring modes DC, PAD, flexIPAD and CV. For use with intelligent IC Vario instruments – or Conductivity as independent detector for & conductivity and amperometric detection. Amperometry Ion chromatography 187 Inline Eluent Preparation – Introduction Inline Eluent Preparation Inline Eluent Preparation increases the duration of unat- tended operation in that with this system, the exhausted eluent is refilled fully automatically while the ion chromatograph is in operation. The eluent is diluted in por- tions with ultrapure water from an eluent concentrate for this purpose. For automatic Inline Eluent Preparation, the 940 Profes- sional IC Vario intelligent ion chromatography systems or the instruments in the Compact IC line need only be expanded to include a 941 Eluent Production Module. While the latter monitors the eluent fill level, the 800 Dosino is responsible for all dosing and Liquid Handling tasks. Tests with injections of 250 µg/L standard solutions, spread out over a time period of approximately 20 days, have demonstrated outstanding stability with respect to retention times. After more than 800 sample injections, the relative standard deviations for a series of anions and cations were less than 0.55 and 0.41 percent, respectively. During a test sequence over a 24-hour period, the precision of the retention times for anions and cations were better than 0.09 and 0.08 percent, respectively. In short, Inline Eluent Preparation with the 941 Eluent Pro- duction Module increases the reproducibility of retention times, thus permitting the exact analysis of anions and cations over extended periods, and does so without manual eluent production. 188 Ion chromatography 941 Eluent Production Module The 941 Eluent Production Module enables the auto- matic production of an eluent. It enables continuous working without manual intervention and guarantees stable retention times. It can be combined with all Metrohm IC instruments and is monitored by MagIC Net. The 941 Eluent Production Module is equipped for the production of an eluent and contains an 800 Dosino. Additional eluents can be produced and monitored when it is expanded to include an 800 Dosino with the IC equipment for additional eluents (6.5330.090). In addition, it offers the possibility of directly connecting an ultrapure water system (ELGA PURELAB® flex 5 or flex 6). • „Inline Eluent Preparation“ • Enhances laboratory safety • Protects eluents against idle running • Can be used for all types of eluents • Simple assembly and configuration • Guarantees stable retention times • Uninterrupted working without manual intervention Ordering Information 941 Eluent Production Module 2.941.0010 941 Eluent Production Module Ion chromatography 189 Extension Module Vario – Overview Suppression Sample preparation Gradient ONE LQH chemical sequential Prep 2 Prep 3 HPG iPump + PP + Inj. + PP + PP + MSM MCS PP Injector Selector Inj. SPM 2.942.0020 Extension Module Vario Prep 2 − − − − − yes − − 2.942.0040 Extension Module Vario HPG − − − − − − − yes 2.942.0070 Extension Module Vario LQH − yes − − − − − − 2.942.0300 Extension Module Vario ChS/PP − − yes − yes − yes − 2.942.0500 Extension Module Vario SeS/PP − − yes yes yes − − − 2.942.1060 Extension Module Vario ONE/Deg yes − − − − − − − 190 Ion chromatography Extension Module Vario 942 Extension Module Vario Prep 2 (2.942.0020) The 942 Extension Module Vario Prep 2 is an extension module for the Professional IC Vario line of instruments. It multiplies the possibilities of Inline Sample Prepara- 942 tion and Extension Liquid Handling in Module Professional IC Vario sys- tems. Vario Prep 2 942 Extension Module Vario HPG (2.942.0040) The 942 Extension Module Vario HPG is an extension module for the Professional IC Vario line of instruments. It permits the addition of a further eluent in a Professional 942 IC Vario Extension high-pressure gr Module adient system. Vario HPG 942 Extension Module Vario LQH (2.942.0070) The 942 Extension Module Vario LQH is an extension module for the Professional IC Vario line of instruments. It expands the possibilities of Metrohm Inline Sample Preparation „MISP“ and Liquid Handling and opens 942 a Pr Extension ofessional IC system for Module Online Monitoring. Vario LQH 942 Extension Module Vario ChS/PP (2.942.0300) The 942 Extension Module Vario ChS/PP is an extension module for the Professional IC Vario line of instruments. It permits the integration of a complete chemical sup- 942 pression Extension with a peristaltic Module pump for suppressor rege- neration or Inline Neutralization or Inline Cation Vario Removal, r ChS/PP espectively, in a Professional IC Vario system. Ion chromatography 191 942 Extension Module Vario SeS/PP (2.942.0500) The 942 Extension Module Vario SeS/PP is an extension module for the Professional IC Vario line of instruments. It permits the integration of a complete sequential 942 suppr Extension ession with Module peristaltic pump for suppressor regeneration in a Professional IC Vario system. Vario SeS/PP 942 Extension Module Vario ONE/Deg (2.942.1060) The 942 Extension Module Vario ONE/Deg is an extension module for the Professional IC Vario line of instruments. It permits the installation of an additional IC analysis 942 channel Extension in a Professional IC V Module ario system. Vario ONE/Deg 192 Ion chromatography Compact IC Flex – Instruments Compact IC Flex – Introduction The intelligent instrument generation of the trols all system components and permits the monitoring Compact ion chromatographs of all relevant parameters. 930 Compact IC Flex and 883 Basic IC plus Depending on the version selected, the 930 Compact IC Flex instruments are equipped with chemical or sequen- Intelligent. Safe. Precise. tial suppression, one column oven and eluent and sam- ple degassers. The type of detection can be selected to The top model for ion chromatography from Metrohm is suit. That is the reason why no detector is included in the the 940 Professional IC Vario. Its intelligent system com-scope of delivery of the Compact IC instruments. ponents set standards with respect to the precision of the results and operating convenience. This technology is The 883 Basic IC plus is the optimum instrument for also available in the intelligent generation of the Com-training purposes. It can be operated only with the sup- pact line of instruments. The 930 Compact IC Flex is plied IC Conductivity Detector. oriented to users from all industries that have a defined need for analysis. Determination of anions, cations and Access to the new online configurator for the 930 Com-polar substances in the µg/L to g/L range is accurate and pact IC Flex instruments is through ic930.metrohm.com securely possible. All intelligent functions of the Professional IC Vario instrument series are also integrated in the 940 Compact Flex and 883 Basic instruments: iPump, iDetector, iColumn technology. They guarantee precise results and exclude the possibility of operator errors to a maximum extent. The MagIC Net chromatography software con- Ion chromatography 193 Compact IC Flex – Overview Suppression 863 Column Automation Autosampler Software chemical sequential Degasser oven capability included included MSM MCS PP 2.930.1100 Compact IC Flex − − − − − yes − − 2.930.1160 Compact IC Flex Deg − − − − yes yes − − 2.930.1200 Compact IC Flex ChS yes − − − − yes − − 2.930.1260 Compact IC Flex ChS/Deg yes − − − yes yes − − 2.930.1300 Compact IC Flex ChS/PP yes − yes − − yes − − 2.930.1360 Compact IC Flex ChS/PP/Deg yes − yes − yes yes − − 2.930.1400 Compact IC Flex SeS yes yes − − − yes − − 2.930.1460 Compact IC Flex SeS/Deg yes yes − − yes yes − − 2.930.1500 Compact IC Flex SeS/PP yes yes yes − − yes − − 2.930.1560 Compact IC Flex SeS/PP/Deg yes yes yes − yes yes − − 2.930.2100 Compact IC Flex Oven − − − yes − yes − − 2.930.2160 Compact IC Flex Oven/Deg − − − yes yes yes − − 2.930.2200 Compact IC Flex Oven/Chs yes − − yes − yes − − 2.930.2260 Compact IC Flex Oven/ChS/Deg yes − − yes yes yes − − 2.930.2300 Compact IC Flex Oven/ChS/PP yes − yes yes − yes − − 2.930.2360 Compact IC Flex Oven/ChS/PP/Deg yes − yes yes yes yes − − 2.930.2400 Compact IC Flex Oven/SeS yes yes − yes − yes − − 2.930.2460 Compact IC Flex Oven/SeS/Deg yes yes − yes yes yes − − 2.930.2500 Compact IC Flex Oven/SeS/PP yes yes yes yes − yes − − 2.930.2560 Compact IC Flex Oven/SeS/PP/Deg yes yes yes yes yes yes − − 2.883.0020 Basic IC plus yes − yes − − yes − yes 2.883.1020 Basic IC plus Package yes − yes − − yes yes yes 194 Ion chromatography Compact IC Flex 930 Compact IC Flex (2.930.1100) The 930 Compact IC Flex is the intelligent Compact IC instrument without suppression. The instrument can be used with any separation and detection methods. 930 Compact IC Flex 930 Compact IC Flex Deg (2.930.1160) The 930 Compact IC Flex Deg is the intelligent Compact IC instrument without suppression with built-in degasser. The instrument can be used with any separa-930 tion and Compact detection methods. IC Flex Deg 930 Compact IC Flex ChS (2.930.1200) The 930 Compact IC Flex ChS is the intelligent Compact IC instrument with chemical suppression. An 800 Dosino can be used for the regeneration of the suppres- 930 sor. The Compact instrument can be IC used Flex with any ChS separation and detection methods. 930 Compact IC Flex ChS/Deg (2.930.1260) The 930 Compact IC Flex ChS/Deg is the intelligent Com- pact IC instrument with chemical suppression and built-in degasser. An 800 Dosino is used for the regen-930 eration Compact of the suppressor. IC The Flex instrument ChS/ can be used with any separation and detection methods. Deg Ion chromatography 195 930 Compact IC Flex ChS/PP (2.930.1300) The 930 Compact IC Flex ChS/PP is the intelligent Com- pact IC instrument with chemical suppression and a peristaltic pump for regeneration. The instrument can 930 be used Compact with any separation IC and Flex detection ChS/ methods. PP 930 Compact IC Flex ChS/PP/Deg (2.930.1360) The 930 Compact IC Flex ChS/PP/Deg is the intelligent Compact IC instrument with chemical suppression and a peristaltic pump for regeneration and a built-in 930 Compact degasser. The instrument IC can be Flex used with ChS/ any separa- tion and detection methods. PP/Deg 930 Compact IC Flex SeS (2.930.1400) The 930 Compact IC Flex SeS is the intelligent Compact IC instrument with sequential suppression. An 800 Dosino can be used for the regeneration of the suppres- 930 sor. The Compact instrument can be IC used Flex with any SeS separation and detection methods. 930 Compact IC Flex SeS/Deg (2.930.1460) The 930 Compact IC Flex SeS/Deg is the intelligent Com- pact IC instrument with sequential suppression and built-in degasser. An 800 Dosino can be used for the 930 regener Compact ation of the suppr IC essor. Flex The SeS/ instrument can be used with any separation and detection methods. Deg 196 Ion chromatography 930 Compact IC Flex SeS/PP (2.930.1500) The 930 Compact IC Flex SeS/PP is the intelligent Com- pact IC instrument with sequential suppression and a peristaltic pump for suppressor regeneration. The in-930 strument Compact can be used with IC any Flex separation SeS/ and detection methods. PP 930 Compact IC Flex SeS/PP/Deg (2.930.1560) The 930 Compact IC Flex SeS/PP/Deg is the intelligent Compact IC instrument with sequential suppression and a peristaltic pump for suppressor regeneration, in 930 addition Compact to a built-in IC degasser. Flex The SeS/ instrument can be used with any separation and detection methods. PP/Deg 930 Compact IC Flex Oven (2.930.2100) The 930 Compact IC Flex Oven is the intelligent Compact IC instrument with column oven and without sup- pression. The instrument can be used with any separa-930 tion and Compact detection methods. IC Flex Oven 930 Compact IC Flex Oven/Deg (2.930.2160) The 930 Compact IC Flex Oven/Deg is the intelligent Compact IC instrument with column oven, without suppression and with built-in degasser. The instru-930 ment Compact can be used with any IC separFlex ation and detection methods. Oven/Deg Ion chromatography 197 930 Compact IC Flex Oven/ChS (2.930.2200) The 930 Compact IC Flex Oven/ChS is the intelligent Compact IC instrument with column oven and chemi- cal suppression. An 800 Dosino can be used for the 930 regener Compact ation of the suppr IC essor. Flex The instrument can be used with any separation and detection methods. Oven/ChS 930 Compact IC Flex Oven/ChS/Deg (2.930.2260) The 930 Compact IC Flex Oven/ChS/Deg is the intelligent Compact IC instrument with column oven, chemical suppression and built-in degasser. An 800 Dosino can 930 be used Compact for the regeneration IC of Flex the suppressor. The in- strument can be used with any separation and detection Oven/ChS/Deg methods. 930 Compact IC Flex Oven/ChS/PP (2.930.2300) The 930 Compact IC Flex Oven/ChS/PP is the intelligent Compact IC instrument with column oven, chemical suppression and a peristaltic pump for suppressor 930 regener Compact ation. The instrument IC can Flex be used with any sepa- ration and detection methods. Oven/ChS/PP 930 Compact IC Flex Oven/ChS/PP/Deg (2.930.2360) The 930 Compact IC Flex Oven/ChS/PP/Deg is the intelli- gent Compact IC instrument with column oven, chem- ical suppression and a peristaltic pump for suppres-930 sor r Compact egeneration and built-in IC Flex degasser. The instrument can be used with any separation and detection methods. Oven/ChS/PP/Deg 198 Ion chromatography 930 Compact IC Flex Oven/SeS (2.930.2400) The 930 Compact IC Flex Oven/SeS is the intelligent Compact IC instrument with column oven and sequen- tial suppression. An 800 Dosino can be used for the 930 regener Compact ation of the suppr IC essor. Flex The instrument can be used with any separation and detection methods. Oven/SeS 930 Compact IC Flex Oven/SeS/Deg (2.930.2460) The 930 Compact IC Flex Oven/SeS/Deg is the intelligent Compact IC instrument with column oven, sequential suppression and built-in degasser. An 800 Dosino can 930 be used Compact for the regeneration IC of Flex the suppressor. The in- strument can be used with any separation and detection Oven/SeS/Deg methods. 930 Compact IC Flex Oven/SeS/PP (2.930.2500) The 930 Compact IC Flex Oven/SeS/PP is the intelligent Compact IC instrument with column oven, sequential suppression and peristaltic pump for suppressor 930 regener Compact ation. The instrument IC can Flex be used with any sepa- ration and detection methods. Oven/SeS/PP 930 Compact IC Flex Oven/SeS/PP/Deg (2.930.2560) The 930 Compact IC Flex Oven/SeS/PP/Deg is the intelli- gent Compact IC instrument with column oven, sequential suppression, a peristaltic pump for sup-930 pressor r Compact egeneration and IC built-in Flex degasser. The instru- ment can be used with any separation and detection Oven/SeS/PP/Deg methods. Ion chromatography 199 Basic IC plus – Instruments 883 Basic IC plus (2.883.0020) The 883 Basic IC plus is an intelligent, very compact ion chromatograph for education and routine analysis. For determining cations and anions with and without chemi-883 cal suppr Basic ession. IC plus Conductivity Detector, MagIC Net Basic software and textbook included. 883 Basic IC plus Package (2.883.1020) Package for automated analysis with the 883 Basic IC plus. For education and routine analysis. For determining cations and anions with and without chemical suppres- 883 sion. Basic 883 Basic IC IC plus, plus 863 P Compact ackage IC Autosampler, MagIC Net Basic software and textbook included. 200 Ion chromatography Additional IC Vario components Alternative IC components – Introduction Ion chromatography has established itself in laboratories as a high-performance and flexible method. The range of analytes that can be determined is improved with addi- tional IC components, and sensitivity and selectivity can be improved as well. Heatable modules can be used not only for Metrohm Inline Sample Preparation (MISP) but also for post- column reaction systems. Data converters enable the import of external detector signals. On the other hand, analog signals can be output to external evaluation sys- tems with the 891 Professional Analog Out. Ion chromatography 201 Heatable reactors and column compartments 943 Professional Reactor Vario (2.943.0110) The 943 Professional Reactor Vario is a heatable reactor, especially developed for pre- and post-column derivatiza- tion. It captivates by its robustness, the fast heating rate 943 and the Professional possibility of carrying out Reactor reactions at up to 150 °C. Vario 943 Professional Thermostat Vario (2.943.0210) The 943 Professional Thermostat Vario is a stand-alone column oven for up to two columns with a maximum length of 150 mm. It captivates by its fast heating rate 943 and the Professional possibility of operating two Thermo separation - columns together at up to 80 °C. stat Vario 202 Ion chromatography Data Converters 771 IC Compact Interface (2.771.0010) The universally applicable analog-digital converter with two channels and 24 Bit resolution. The data is passed along to the PC through the RS-232C interface and can 771 be pr IC ocessed Compact further there with Interface IC Net or with MagIC Net. 771 IC Compact Interface; MagIC Net Professional (2.771.0110) IC Compact Interface with the MagIC Net Professional software. The 771 Compact Interface combines the ana-771 log IC signal of Compact the existing IC Interface; instruments (Compact, Modular, Advanced) with the improved possibilities of MagIC the modern Net™ MagIC Net Pr software. ofessional 771 IC Compact Interface; MagIC Net Compact (2.771.0210) IC Compact Interface with the MagIC Net Compact soft- ware. The 771 Compact Interface combines the analog 771 signal of IC the Compact existing IC Interface; instruments (Compact, Modular, Advanced) with the improved possibilities of the modern MagIC MagIC Net Net™ software. Compact 891 Professional Analog Out (2.891.0010) The 891 Professional Analog Out is an additional module for intelligent IC instruments. It allows to transfer analog signals of different chromatographic data to external 891 data Pr systems. ofessional Analog Out Ion chromatography 203 Professional IC Vario – Hyphenated systems IC Vario coupling techniques – Introduction The world of ion chromatography is extended con- siderably when Metrohm IC is coupled with other analy- sis methods, sample preparation techniques or detection systems. The possibilities are practically unlimited. Any system that can process or supply aqueous solutions as samples can be coupled to Metrohm IC instruments. This means that ion chromatography can be combined with Metrohm titrators and measuring instruments to form hyphenated systems. These TitrIC Vario or VoltIC Vario systems enable, for example, the entire water anal- ysis, down to ion balance, simultaneously from a single sample. Additional typical examples include the coupling of the IC with MS or ICP-MS, the Combustion IC and air monitoring systems. 204 Ion chromatography Hyphenated IC systems TitrIC Vario pro I – The basic hyphenated system for IC and titration (TitrIC Vario pro I) Fully automatic system for direct measurement of temperature, conductivity and pH value; the titrimetric deter-TitrIC mination of Vp ario value, m pro value, I – calcium The and magnesium and the determination of anions by ion chromatography. basic hyphenated system for IC and titration TitrIC Vario pro II – The hyphenated IC and titration system for comprehensive anion and cation analysis (TitrIC Vario pro II) Fully automatic system for direct measurement of tem-TitrIC perature, Vario conductivity pr and o pH II value; – the The titrimetric deter- mination of p and m value, the determination of cations hyphenated including calcium and IC and magnesium, as titr well as ati- anions by ion chromatography. on system for compre- hensive anion and cation TitrIC Vario pro III – The professional hyphenated IC and titration system with lockable sample vessels (TitrIC Vario pro III) Fully automatic system for direct measurement of temperature, conductivity and pH value; the titrimetric deter-analysis TitrIC mination of V p ario and m pr value, o the III – The determination of cations professional including calcium and hyphenated magnesium, as well as anions by ion chromatography. The sample changer is equipped IC with and the titr DisCover ation function for system automatic sample vessel with cover r lockable emoval. sample ves- VoltIC Vario pro I – The hyphenated IC and voltammetry system for parallel determination of anions, cations and heavy metals (VoltIC Vario pro I) VoltIC Vario I is the perfect combination of IC and voltammetry for simultaneous determination of anions, sels VoltIC cations and Vario heavy pr metals. o I MagIC – Net The controls IC in- hyphenated struments, starts IC voltammetric and determination, and sum- marizes the results from IC and voltammetry. voltammetry system for parallel determination of anions, cations and heavy metals Ion chromatography 205 930 Metrohm Combustion IC (2.930.9010) The 930 Metrohm Combustion IC enables the analysis of halogens and sulfur in flammable samples of all types using inline combustion digestion with subsequent ion 930 chr Metr omatography ohm Combusti determination (Combustion IC). -It in- cludes all required components. If necessary, the 930 on Metr IC ohm Combustion IC package can be supplemented with an Autosampler for solid or liquid samples (MMS 5000 Autosampler). The entire analysis, including sample input and combustion, is completely controlled by MagIC Net. 920 Absorber Module (2.920.0010) The 920 Absorber Module combines the Combustion Module with the ion chromatograph. The 920 Absorber Module ensures that the gaseous compounds of the 920 analytes Absorber are dissolved and Module channeled to the IC. It is re- sponsible for the entire Liquid Handling. In addition to Combustion IC, it can also be used for gas analysis. MMS 5000 Autosampler (2.136.0800) MMS 5000 Autosampler from Analytik Jena for use with the Metrohm Combustion IC for fully automatic analysis of liquid and solid samples. In order to match the modu- MMS lar 5000 Multi-Matrix sampler Autosampler with the correct sample type, either the liquid kit (6.7303.000) or the solid kit (6.7302.000) must be used. Combustion Module ( Oven + ABD ) (2.136.0700) The Combustion Module (Oven + ABD ) enables the sample digestion of flammable samples of all types under pyrolysis and oxidation. The Combustion Module is com- Combustion prised of the combustion Module oven and the ( Auto Boat Driver (automatic sample introduction). Both are products of Oven Analytik + Jena ABD which have )been optimized specially for coupling with ion chromatographs. 206 Ion chromatography Auto Boat Drive (2.136.0710) The Auto Boat Drive (ABD) automatically guides the sam- ple scoops into the combustion oven. The sample injec- tion into the boat can proceed manually or with a corre- Auto sponding Boat sampler. Drive The Analytik Jena product has been optimized specially for coupling with ion chromato- graphs. LPG/GSS Module (2.136.0720) The LPG/GSS Module is a sample injection system for either liquefied gases or gases under enhanced pressure. The module is controlled automatically and moves the LPG/GSS respective Module amounts of gas to the combustion oven for combustion. The Analytik Jena product has been optimized specially for coupling with ion chromatographs. Combustion Module (Oven + LPG/GSS) (2.136.0730) The Combustion Module (Oven + LPG/GSS) enables sam- ple digestion during the pyrolysis of liquefied gases and gases under pressure. The Combustion Module (Oven + Combustion LPG/GSS) is comprised of Module the combustion oven and the LPG/GSS module. Both are products of Analytik Jena (Oven which have + LPG/GSS) been optimized specially for coupling with ion chromatographs. PILS, Particle Into Liquid Sampler (2.136.0400) Coupling with ion chromatographs allows automatic determination of the ionic composition of the aerosols without requiring additional sample preparation. PILS, Particle Into Liquid Sampler Ion chromatography 207 MARGA, Monitor for AeRosols and Gases in ambient Air (MARGA) MARGA is a fully automated online system that determines anions and cations in gases and aerosols. The acid MARGA, and alkali gases are Monitor absorbed in water for in a „Wet Rotating Denuder“ and the aerosols in a „Steam Jet Aerosol Col- AeRosols lector“ and and investigated with Gases two Compact in ICs for their anion and cation content. MARGA is designed for pro- ambient longed Air autonomous operation. MARGA is distributed by Applikon (www.metrohm- applikon.com). 208 Ion chromatography Automation in ion chromatography Overview of IC automation Sample changers Metrohm Inline Sample Preparation (MISP) Automation in ion chromatography ranges all the way Samples such as milk, chocolate, caustic soda, biodiesel from simple automatic sample injection to complex sam-or heavily contaminated waste waters require sample ple preparation with combined methods. It must be preparation before they can be analyzed with IC. possible to process sample quantities ranging from a few Together with the 858 Professional Sample Processor, the µL to several mL. A number of sample changers with 940 Professional IC Vario offers extensive possibilities for different areas of application are available for this pur-completely automated Inline Sample Preparation, e.g., pose. Inline Ultrafiltration, Inline Dialysis, Inline Preconcentration, Inline Matrix Elimination, Inline Matrix Neutralization and The 858 Professional Sample Processor is more than just Inline Calibration. a sample changer. Equipped with pumps, high-pressure valve and Dosinos, it makes an integral contribution to Inline Sample Preparation and Liquid Handling. In addition to the 858 Professional Sample Processor, the 889 IC Sample Center, the 919 IC Autosampler plus, the 863 Compact IC and the entire series of the 814 and 815 Sample Processors are available from the titration range. Ion chromatography 209 IC Automation – Instruments 858 Professional Sample Processor (2.858.0010) The 858 Professional Sample Processor processes sam- ples from 500 µL to 500 mL. The sample transfer takes place either by means of a peristaltic pump on the 850 858 Pr Pr ofessional ofessional IC system or with an Sample 800 Dosino. Processor 858 Professional Sample Processor – Pump (2.858.0020) The 858 Professional Sample Processor – Pump processes samples from 500 µL to 500 mL. The sample transfer 858 takes Pr place ofessional either with the Sample installed bidirectional two- channel peristaltic pump or with an 800 Dosino. Processor – Pump 858 Professional Sample Processor – Pump – Injector (2.858.0030) The 858 Professional Sample Processor – Pump – Injector processes samples from 500 µL to 500 mL. The sample 858 transfer Pr takes ofessional place either with the Sample installed bidirectional two-channel peristaltic pump or by means of an 800 Processor Dosino. In addition, – a Pump six-way injection – Injec valve is - available for the sample preparation. tor 919 IC Autosampler plus (2.919.0020) The 919 IC Autosampler plus fulfills the requirements of laboratories with medium sample numbers. It enables automation of the full range of Metrohm IC instruments. 919 IC Autosampler plus 210 Ion chromatography 863 Compact IC Autosampler (2.863.0010) The 863 Compact IC Autosampler is the ideal help for routine analysis. It enables automation of the full range of Metrohm IC instruments. 863 Compact IC Auto- sampler 815 Robotic Soliprep for LC (2.815.4110) The 815 Robotic Soliprep for LC is a complete system for the completely automatic preparation of samples which need to be dissolved, homogenized, diluted or filtered 815 prior to Robotic their Solipr determination. The ep samples ar for e conveyed directly into the injector of the chromatograph after pre- LC paration. 889 IC Sample Center (2.889.0010) The 889 IC Sample Center is a robust Autosampler for high sample throughput, optimized for the challenges of the modern analytic laboratory. It works in accordance 889 with the IC x-y-z Sample principle and a Center syringe control with high resolution for precise sample injection. A double needle system enables the penetration of vessel caps and septa. A PEEK injection valve completes the automation system of the 889 IC Sample Center. It is the appropriate auto- mation solution when you have only a very small amount of sample. 889 IC Sample Center – cool (2.889.0020) The 889 IC Sample Center – cool is the appropriate auto- mation solution when you have only a very small amount of sample. In comparison with the 889 IC Sample Center, 889 it IC possesses in Sample addition a Center cooling function and – is thus the ideal sample changer for biochemical y relevant or cool thermally unstable samples. Ion chromatography 211 Additional Sample Processors for IC Even more flexibility and choice! The system works through the prepared samples, no Even the USB Sample Processors of the titration segment matter what time of day it is. Whether it be automatic can be actuated with MagIC Net. This means that there sample preparation, Liquid Handling or sample process-are practically no limits to automation in ion chromatog- ing – this Sample Processor generation controls eve-raphy. Whether it be small or large sample vessels, rything that one previously associated only with labora-whether it be at room temperature or cooled, whether it tory robots. be automatic sample preparation with one or two sam- ple changer towers – the answer in ion chromatography Depending on preference, the USB Sample Processor can is always: be controlled not only with MagIC Net but also with Touch Control, PC Control or conveniently with the Yes, we can do it! tiamo TM titration software. The advantages of a sample changer lie not only in the time savings for the laboratory personnel: Automatic systems control operating sequences and thus improve reproducibility and accuracy. Errors can be reduced to a minimum. Ordering Information 2.814.0010 814 USB Sample Processor (1T/1P) 2.814.0020 814 USB Sample Processor (1T/2P) 2.814.0030 814 USB Sample Processor (1T/0P) 2.814.0110 814 USB Sample Processor (2T/2P) 2.814.0120 814 USB Sample Processor (2T/4P) 2.814.0130 814 USB Sample Processor (2T/0P) 2.815.0010 815 Robotic USB Sample Processor XL (1T/1P) 2.815.0020 815 Robotic USB Sample Processor XL (1T/2P) 2.815.0030 815 Robotic USB Sample Processor XL (1T/0P) 2.815.0110 815 Robotic USB Sample Processor XL (2T/2P) 2.815.0120 815 Robotic USB Sample Processor XL (2T/4P) 2.815.0130 815 Robotic USB Sample Processor XL (2T/0P) 2.815.2110 815 Robotic Flexible Soliprep 814 USB Sample Processor with sample rack for 12 x 250 mL 2.815.3110 815 Robotic Filtration Soliprep 212 Ion chromatography Liquid Handling in ion chromatography Liquid Handling in IC – Introduction Sample input – Inline Sample Preparation In the beginning was the syringe – manual sample injection continues to be used today. In most cases, however, the samples are transferred automatically into the ion chromatograph. It begins with the simple peristaltic pump that pumps the sample solution to the injector. Additional components, e.g., valves, filtration and dialy- sis cells, neutralization modules, etc. thus pave the way to Inline Sample Preparation. The use of the 800 Dosino as module for sample transfer, also and in particular for the exact dosing of several solutions and different volumes, represents yet another massive extension of these possibilities. Logical and flexible dilution – that means free selection of dilution factor and repeated dilution of the sample when the result lies outside of the calibration range – high-precision „Partial-Loop Injection“ methods and automatic calibration with variable preconcentration – enables a calibrated working range of up to six decades (e.g., 10 ppt to 10 ppm); these are only a few of the many applications that only became possible with the advent of the 800 Dosino. IC equipment for Liquid Handling MISP made simple. The IC equipments contain all of the parts required for the respective sample preparation method. This way you can be sure that the method also works. Ion chromatography 213 Liquid Handling for IC 800 Dosino (2.800.0010) Drive with write/read hardware for intelligent Dosing Units. With fixed cable (length 150 cm). 800 Dosino 846 Dosing Interface (2.846.0010) USB-capable control unit for connecting a maximum of four 800 Dosinos or 805 Dosimats for dosing and Liquid Handling tasks. A Touch Control or the connection to a 846 PC with Dosing tiamo™, MagIC Interface Net, viva or 797 VA Computrace is required for operation. IC equipment: Additional eluent on the Eluent Production Module (6.5330.090) Accessory set for Eluent Production Module. Contains all parts necessary for expansion by one eluent. The level IC equipment: sensor must be ordered in Additional accordance with the applica- tion. eluent on the Eluent Pro- duction Module IC equipment: Inline dialysis (6.5330.100) Accessory set for Inline Dialysis. For use with the 858 Professional Sample Processor and an additional 2-chan- nel peristaltic pump. IC equipment: Inline dialy- sis 214 Ion chromatography IC equipment: Inline ultrafiltration (6.5330.110) Accessory set for Inline Ultrafiltration. For use with the 858 Professional Sample Processor. IC equipment: Inline ultra- filtration IC equipment: Inline dilution (6.5330.120) Accessory set for Inline Dilution. For use with the 858 Professional Sample Processor, 800 Dosino and 741 Magnetic Stirrer. IC equipment: Inline dilu- tion IC equipment: Liquid Handling Station, left (6.5330.130) Accessory set for assembling the Liquid Handling Station on the Professional Sample Processor. The rinsing water IC equipment: supply can be accomplished Liquid by means of a peristaltic pump or a Dosino. Handling Station, left IC equipment: MiPCT (6.5330.140) Accessory set for Inline Preconcentration (MiPCT) includ- ing Liquid Handling Station, left. IC equipment: MiPCT Ion chromatography 215 IC equipment: Dose-in Gradient (6.5330.150) Accessory set for assembling the Dose-in Gradient. IC equipment: Dose-in Gradient IC equipment: MiPCT-ME (6.5330.160) Accessory set for assembling a Dosino for Metrohm intel- ligent Preconcentration Technique with Matrix Elimination (MiPCT-ME). IC equipment: MiPCT-ME IC equipment: MiPUT (6.5330.170) Accessory set for assembling a Dosino for Sample Pickup. IC equipment: MiPUT IC equipment: MiPT (6.5330.180) Accessory set for assembling a Dosino for Partial-Loop- Injection. IC equipment: MiPT 216 Ion chromatography IC equipment: Dosino regeneration (6.5330.190) Accessory set for the assembly of a Dosino for automatic regeneration of the Metrohm Suppressor Module (MSM). IC equipment: Dosino regeneration IQ/OQ Kit for IC (6.5333.000) The IQ/OQ Kit contains all parts and standard solutions required for IQ/OQ in ion chromatography. IQ/OQ Kit for IC IC equipment for Liquid Handling Set for PILS (6.5335.000) Accessories set for PILS (Particle Into Liquid Sampler). IC equipment for Liquid Handling Set for PILS Peristaltic pump, 8-channel (2.136.0500) 8-channel peristaltic pump for PILS (Particle Into Liquid sampler) for transferring any auxiliary solution. Peristaltic pump, 8-chan- nel Ion chromatography 217 Professional Vario IC – Software MagIC Net – Introduction MagIC Net software for intuitive and simple op- all of the information required is made available immedi- eration ately. It‘s MagIC! All intelligent components are recognized, monitored Clear symbols, clear presentation, intuitive operation, and actuated automatically: „One-Button IC“: This is MagIC Net. • IC Amperometric Detector Complete system monitoring, control charts for measure- • IC Conductivity Detector ments, convenient database functions: This, too, is • iCell MagIC Net, the intelligent software – Swiss Made – for • iColumns controlling and monitoring the Metrohm ion chroma- • iReactor tography systems. • 771 Compact Interface • 800 Dosinos The MagIC Net chromatography software controls all • 814/815 Robotic USB Sample Processors intelligent ion chromatographs and records all the data • 846 Dosing Interface that arises. The current version of MagIC Net is offered in • 850 Professional IC four different versions: • 858 Professional Sample Processor • 863 Compact IC Autosampler • MagIC Net Professional supports the entire range of • 872 Extension Module intelligent ion chromatographs and sample changers. • 881 Compact IC pro This means that all of the peripheral devices for Inline • 882 Compact IC plus Sample Preparation and Liquid Handling can also be • 883 Basic IC plus operated and other Metrohm instruments or third- • 886 Professional Reactor / Thermostat party devices that are already in use can be remote- • 887 Professional UV/VIS Detector controlled. • 889 IC Sample Center • MagIC Net Compact comprises the complete function- • 891 Professional Analog Out ality of the MagIC Net Professional version. However, • 896 Professional Detector only the Compact IC instruments and one sample • 919 IC Autosampler plus changer can be connected for automation purposes. • 930 Compact IC Flex • MagIC Net Multi makes MagIC Net Professional availa- • 940 Professional IC Vario ble in its entirety as a client-server installation. • 941 Eluent Production Module • MagIC Net Basic is a special version for the 883 Basic • 942 Extension Module Vario IC plus, modified for training requirements. MagIC Net • 943 Professional Reactor/Thermostat Vario Basic is contained in the instrument. • 944 Professional UV/VIS Detector Vario • 945 Professional Detector Vario All four versions are exceptional for their clearly organ- ized presentation, clear symbols and intuitive operation. Flexible programming of the sequences in the time pro-The checking and monitoring functions of the MagIC Net grams, combined with logical decisions and virtually software are unique: All system parameters, service inter-infinite calculation possibilities, open up the entire world vals or expiration data can be checked, as can also all of ion chromatography with MagIC Net. From simple measuring results of samples and standard solutions. routine applications all the way to highly complex com-When a limit value is exceeded, previously defined binations of different sample preparation techniques. actions, e.g., the sending of a message via e-mail or cellular phone or the switching off of the system, can be triggered. Thanks to the modern data management of MagIC Net, one never loses sight of the larger picture, as 218 Ion chromatography MagIC Net versions MagIC Net 3.0 Compact CD: 1 license (6.6059.301) Professional PC program for controlling an intelligent Compact IC instrument, one detector and one Autosampler, or a 771 Compact Interface. The software per- MagIC mits control, Net data 3.0 acquisition, Compact data evaluation and data monitoring as well as report generation of ion chromato- CD: graphic 1 license analyses. MagIC Net Compact complies fully with FDA Regulation 21 CFR Part 11 as well as GLP. MagIC Net is available in 14 dialog languages. MagIC Net 3.0 Professional CD: 1 license (6.6059.302) Professional PC program for controlling all of the intelligent Professional IC systems, Compact IC instruments MagIC and their Net peripherals, 3.0 such as Professio various - Autosamplers, 800 Dosino, 771 Compact Interface, etc. The software pernal mits CD: the contr 1 ol, license data acquisition, data evaluation, data monitoring and report generation of ion chromatographic analyses. MagIC Net Professional complies fully with FDA Regulation 21 CFR Part 11 as well as GLP. MagIC Net is available in 14 dialog languages. MagIC Net 3.0 Multi CD: 3 licenses (6.6059.303) Professional PC program for controlling all of the intelligent Professional IC systems, Compact IC instruments and their peripherals, such as various Autosamplers, 800 MagIC Dosino, 771 Net Compact 3.0 Multi Interface, etc. The CD: software per- mits the control, data acquisition, data evaluation, data 3 licenses monitoring and report generation of ion chromatographic analyses. MagIC Net Multi complies fully with FDA Regu- lation 21 CFR Part 11 as well as GLP. MagIC Net is availa- ble in 14 dialog languages. Client/server version with 3 licenses. Metrohm IC Driver for Empower (6.6070.000) Software driver for integrating Metrohm IC instruments in „Empower“ from Waters. Metrohm IC Driver for Empower Ion chromatography 219 Metrohm Quality Service Metrohm Quality Service 221 Metrohm Quality Service Reliable measurement results for the lifetime of Metrohm Compliance Service the instrument The variety of different laboratory instruments and analy- It makes no difference whatsoever whether you perform sis systems in use today makes compliance with statutory water analysis with the 940 Professional IC Vario or trace requirements very complicated for companies operating analysis with VA or whether you determine water con-in the regulated sector. Put your trust therefore in the tents in your pharmaceuticals laboratory with Karl Fischer Metrohm Compliance Service when the time comes for titration, our Metrohm Quality Service ensures that you the professional initial qualification of your analyzers. As can rely 100% on your measurement results for the en-an experienced and trustworthy partner, Metrohm pro- tire lifetime of the instrument. vides your customers rapidly and professionally with everything required for compliance with regulations. Our Preventive maintenance – just as important as qualification and validation documents and our services with your car provide you with support for compliance with the re-Preventive maintenance carried out on a regular basis quirements of FDA regulations, GLP/GMP standards and extends your analysis systems‘ trouble-free lifetime and GAMP directives. operational capability. Qualification training-certified service technicians perform the maintenance work world- wide. You can select between different types of service contracts. A full service contract, for example, offers you maximum security for troublefree work, while giving you complete control of costs and providing fully compliant documentation. 222 Metrohm Quality Service Metrohm Quality Service With Metrohm Quality Service you are on the safe side maintenance and – if problems arise – to quick repair, from day one. From installation to start-up, to regular we guarantee you precise and correct measuring results. Metrohm Quality Service Customer benefits • Minimizes downtime through preventative maintenance • Cost control and savings through free or discounted replacement materials Metrohm Care Contracts and consumables • Guaranteed reaction times and rapid on-site repair • Documented instrument certification as an ideal preparation for audits • High data security and maximum system performance through regular, Metrohm Software Maintenance professional software maintenance • Customized services and documentation for analytical instrument qualification (AIQ) Metrohm Compliance Service • Professional start-up (IQ/OQ or Certified Installation) and requalification or recertification by specifically trained employees Metrohm Remote Support • Quick resolution of software and application issues directly at the workplace • Calibration of burettes (e.g., dosing and exchange units) with certification • Accurate measurement results Metrohm Dosing Test • Verification documentation for compliance with regulations and efficient audits • Rapid availability of repaired instruments thanks to decentralized repair workshops around the world and a central workshop at the manufacturer site Metrohm Repair Service • Highly qualified service technicians ensure sustainable repair success • Rapid resolution of problems and minimized downtimes through on-site emergency services and express repairs • Original spare parts, made in Switzerland and available worldwide • Short delivery times through warehousing from local distributers Metrohm Spare Parts • Investment security through ten-year spare parts guarantee after discontinuation • Access to Metrohm Applications expertise (Application Bulletins, Application Notes, monographs, technical posters and specialized articles) • Rapid and professional resolution of any application issues through personal Metrohm Application Support consultations with our specialists by e-mail, telephone, or remote support • Support for the solution of complex analytical problems, as well as method optimization on-site or at our application laboratory • Basic and advanced training with local representatives, at the Metrohm Academy or directly on-site Metrohm Training Programs • Efficient and proper use of all analytical methods, as well as results reliability through competently trained users • Training documentation and certificates for trouble-free audits Metrohm Quality Service 223 General Catalog www.metrohm.com Herisau CH-9101 G, A ohm Metr by atalog 2014 witzerland S al C in Subject to modifications Printed 8.000.5112EN Gener