For Budget Critical, General Purpose and GLP/GMP Laboratories The Autopol®I, II, and III Automatic Polarimeters United States Department of Commerce National Institute of Standards and Technology NVLAP LAB CODE: 200898-0 Accreditation to ISO/IEC 17025:2005 *The polarimeter brand used in more labs than any other. Meeting the needs of your industry and application • University Education and Research • Flavor, Fragrance and Essential Oil • Food T E C H N I C A L B U L L E T I N 9 3 2 • Chemical *Emmes Survey • Pharmaceutical Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Rudolph Research Analytical serving its customers with Integrity, Quality, and Innovation for over fifty years. Simple Solutions Set up a Method cGMP/GLP Printing Measurement reports can be saved as an Excel or PDF file and edited quickly and easily. You can import logos and print your company’s customized “C of A” directly. Rudolph Research Analytical Tuesday. January 27, 2009 This sample was measured on an Autopol VI serial number 80179, manufactured by Rudolph Research Analytical,Hackettstown, NJ. Set Temperature : 20.0 Temp Corr : OFF n Average Std.Dev. Maximum Minimum 5 34.467 0.0000 34.467 34.467 S.No Time Result Scale OR °Arc WLG Lg.mm Temp. Comment 1 4:32:05 PM 34.467 OR 34.467 589 100.00 20.0 2 4:32:08 PM 34.467 OR 34.467 589 100.00 20.0 3 4:32:10 PM 34.467 OR 34.467 589 100.00 20.0 4 4:32:13 PM 34.467 OR 34.467 589 100.00 20.0 5 4:32:16 PM 34.467 OR 34.467 589 100.00 20.0 Print your customized Certificate of Analysis including your Select a Method company logo directly from the Autopol® touch screen Rudolph Research Analytical Tuesday, January 27, 2009 This sample was measured on an Autopol VI, serial number 80179, manufactured by Rudolph Research Analytical,Hackettstown, NJ. Set Temperature : 20.0 Temp Corr : OFF n Average Std.Dev. Maximum Minimum 5 34.467 0.0000 34.467 34.467 S.No Time Result Scale OR °Arc WLG Lg.mm Temp. Comment 1 4:32:05 PM 34.467 OR 34.467 589 100.00 20.0 2 4:32:08 PM 34.467 OR 34.467 589 100.00 20.0 3 4:32:10 PM 34.467 OR 34.467 589 100.00 20.0 4 4:32:13 PM 34.467 OR 34.467 589 100.00 20.0 5 4:32:16 PM 34.467 OR 34.467 589 100.00 20.0 Capable of making multiple measurements on a single sample and reporting complete statistical data and all measurement results Select a Temperature Versatile Communication Capability • Connect directly to Rudolph’s service department for remote testing and diagnostics via Internet connection. • Connect to any Windows® based printer via USB or direct to the server via Windows® Print Library • Save measurement data direct to your Network/Server Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Select the Model that Best Suits your Application and Budget Autopol I The Autopol I is our entry-level polarimeter model designed for: • University Education • Natural Product Research • Starch Analysis • Invert Sugar • Lactose in Milk • Vitamins • Flavors • Fragrance • Chemicals Standard Features: 0.01° Arc Accuracy, 589nm fixed wavelength, built in thermoprobe for temperature measurement, Windows Embedded 7 for direct connection to the network server and flexible USB printing. Optional Features: • TempTrol™ heating and cooling: 15°C – 40°C ±.2°C • AP Accuracy Option: 0.004° Arc Optical Rotation • AP Resolution Option: 0.01, 0.001°Arc Selectable Autopol II The Autopol II offers the same standard and optional features as the Autopol I, but allows greater wavelength flexibility. Standard Wavelengths: 589nm and 546nm Optional Wavelengths: 365nm, 405nm, 436nm, 578nm, 633nm A total of 2-4 extra wavelengths may be ordered at time of purchase or added later when needed. Optional Features: • 100mm or 200mm TempTrol™ heating and cooling: 15°C – 40°C ±.2°C • AP Accuracy Option: 0.004° Arc Optical Rotation • AP Resolution Option: 0.01, 0.001°Arc Selectable Autopol III The Autopol III is Rudolph’s entry level pharmaceutical solution: Accuracy: 0.002°C, 0.2% above 1° Standard Wavelengths: 589nm and 546nm Complete Accessory Package with IQOQPQ documentation, 2 user selectable cells and 1 NIST traceable calibration standard with NIST Certificate. Optional Features: • 100mm or 200mm TempTrol™ heating and cooling: 15°C – 40°C ±.2°C • Optional Wavelengths: 365nm, 405nm, 436nm, 578nm, 633nm, (up to 4 wavelengths may be selected or added later. • AP Accuracy Option: ±0.002ůp to 10° Arc, ±0.004° 10° - 89°Arc • AP Resolution Option: 0.01, 0.001, 0.0001°, Arc Selectable Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Select a Temperature Solution 1. Temperature Measurement Only As shown in Figure A, the Autopol I, II, and III come with a Temperature Probe so that sample temperature can be measured, displayed, and printed. However, if your product requires Temperature control, then we recommend a temperature control solution shown below. For university education and research, starch analysis, invert sugar, flavors, fragrances temperature control is not required and temperature measurement is normally sufficient for these applications. Figure A 2. Temperature Control With Water Bath Glass Stopper Rudolph Research Analytical jacketed cells come standard with quick release fittings which allow cells to be easily removed from the sample chamber. Tubing is held in place by rubber gasketing on top of the trough and the door. Optional stopper (choose “S” after the Figure B cell part no.) for evaporative samples (Figure B). Temperature control is obtained through the use of an external water bath and a jacketed cell (Figure C). This temperature control solution is popular for very high temperature applications. Figure C 3. Patented TempTrol™ Technology Eliminates the Need for a Water Bath. Here’s how the TempTrol Sysytem works: Temperature Place the TempTrol Measurement Port cell in your TempTrol equipped Autopol® sample chamber to measure to within ±0.2°C of the USP, EP, JP or BP specified temperature TempTrol Peltier TempTrol (normally 20°C or 25°C Active Surface Temperature Passive Surface Measurement Probe ±0.5°C) TempTrol heating and cooling TempTrol cell with mating heating Peltier transfer surface and cooling transfer surface Water Inlet Rudolph provides a temperature validation cell with every TempTrol Temperature is selected via touch system. The temperature screen. Temperature selection of validation cell along 20°C shown at left. with an optional NIST traceable thermometer Select temperature up to 40°C NIST is designed to validate Thermometer Probe the temperature control performance of the polarimeter and cell to ±0.2°C. Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Select the Accessories to meet your application Selection With over 50 cells to choose from, Rudolph Research Analytical has a cell to meet every application. Rudolph offers cells with volumes as small as 100 micro liters and cell lengths from 10 mm to 200 mm. Rudolph 40T and 316 stainless steel cells come with lifetime warranty against accidental breakage. Autopol I and II The Autopol I and II come standard with Package A, which includes: Package A 2 lamps and a Type 14 center fill glass cell with a 100 mm length and a 6 ml volume. For validation purposes Rudolph recommends a NIST Traceable Calibration Standard with NIST Certificate to ensure your polarimeter is operating according to specification. (Choose Package B) Package B Autopol III The Autopol III comes standard with 2 lamps, 2 user selectable cells and a calibration standard. Although the user may select from any of our 60 plus cells, popular packages (C, D, and E) are shown below. If TempTrol is selected, Package F is supplied. TempTrolTM Validation NIST Cell Traceable Certificate TempTrolTM Measurement Cell TempTrolTM NIST Traceable Package C Package D Package E Package F Quartz Callibration Standard Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Specifications Markets Education Food Pharmaceutical QC SPECIFICATIONS Autopol I Autopol II Autopol III Optical Rotation, Specific Rotation, Optical Rotation, Specific Rotation, Optical Rotation, Specific Rotation, Measuring Mode Concentration, Sugar Degrees, °Z (ISS) Concentration, Sugar Degrees, °Z (ISS) Concentration, Sugar Degrees, °Z (ISS) Measuring Scale Degrees Arc Optical Rotation Degrees Arc Optical Rotation Degrees Arc Optical Rotation 0.01° Arc Optical Rotation, 0.01% 0.01° Arc Optical Rotation, 0.01% 0.001° Arc Optical Rotation,0.001% Resolution Concentration. 0.01 Specific Rotation Concentration, 0.01 Specific Rotation Concentration, 0.001 Specific Rotation 0.01° Arc Optical Rotation, 0.03°Z (ISS) 0.01° Arc Optical Rotation, 0.03°Z (ISS) 0.002° Arc up to 1°, 0.2% above 1°, Accuracy Sugar Degrees Sugar Degrees 0.01° Z (ISS) AP Accuracy Option Resolution: 0.001° Arc Optical Rotation Resolution: 0.001° Arc Optical Rotation Accuracy: ±0.002ůp to 10°, ±0.004° Reproducibility: 0.002° Arc Optical Rotation, Reproducibility: 0.002° Arc Optical Rotation, 10° - 89° Arc Optical Rotation Accuracy: ±0.004° Arc Optical Rotation Accuracy: ±0.004° Arc Optical Rotation AP Resolution Option Selectable Resolution: 0.01, 0.001, Selectable Resolution: 0.01, 0.001° Arc Selectable Resolution: 0.01, 0.001° Arc 0.0001° Arc Reproducibility 0.01° Arc Optical Rotation 0.01° Arc Optical Rotation 0.002° Arc Optical Rotation Measuring Range ± 89.9° Arc Optical Rotation, ± 999.99° Arc ± 89.9° Arc Optical Rotation, ± 999.99° Arc ± 89.9° Arc Optical Rotation, ± 999.99° Arc Specific Rotation, 0-99.9% Concentration Specific Rotation, 0-99.9% Concentration Specific Rotation, 0-99.9% Concentration Prism Glan Thompson Calcite Glan Thompson Calcite Glan Thompson Calcite 589nm, 546nm standard 589nm, 546nm standard Optical Wavelengths 589nm Optional wavelengths: 365nm, 405nm, Optional wavelengths: 365nm, 405nm, 436nm, 578nm 436nm, 578nm Wavelength Selection Fixed Touchscreen Selectable: Touchscreen Selectable: 2 standard, 4 optional 2 standard, 4 optional 21 CFR Part 11 Compliant Software Yes with optional PC software Yes with optional PC software Yes with optional PC software By external water bath (standard) By external water bath (standard) By external water bath (standard) Temperature Control TempTrolTM Automatic Electric Heating and TempTrolTM Automatic Electric Heating and TempTrolTM Automatic Electric Heating and Cooling 15°- 40°C Cooling 15°- 40°C Cooling 15°- 40°C ±0.2°C (optional) ±0.2°C (optional) ±0.2°C (optional) Temp. Probe Range 10° - 100°C 10° - 100°C 10° - 100°C Temp. Probe Accuracy ±0.1°C ±0.1°C ±0.1°C Measurement Time 5 measurements in less than 25 seconds (avg.) 5 measurements in less than 25 seconds (avg.) 5 measurements in less than 25 seconds (avg.) Tungsten-Halogen 6V, 20W, Tungsten-Halogen 6V, 20W, Tungsten-Halogen 6V, 20W, Light Source avg. 2,000 hour life avg. 2,000 hour life avg. 2,000 hour life Sample Chamber Accepts sample tubes up to 200 mm Accepts sample tubes up to 200 mm Accepts sample tubes up to 200 mm Data Storage 8 GB Non-removable Compact Flash 8 GB Non-removable Compact Flash 8 GB Non-removable Compact Flash Communication 3 – USB Ports, 2 – RS232 Ports, 3 – USB Ports, 2 – RS232 Ports, 3 – USB Ports, 2 – RS232 Ports, Interface Ethernet Port for Network Connection Ethernet Port for Network Connection Ethernet Port for Network Connection Calibration Automatic calibration via touchscreen Automatic calibration via touchscreen Automatic calibration via touchscreen 8” color, 800 x 600 pixel resolution 8” color, 800 x 600 pixel resolution 8” color, 800 x 600 pixel resolution Display with 400 nits of brightness with 400 nits of brightness with 400 nits of brightness User Interface Touchscreen Touchscreen Touchscreen Automatic Sensitivity Measures samples with transmittance Measures samples with transmittance Measures samples with transmittance Control as low as 0.01% (up to O.D. 4.0) as low as 0.01% (up to O.D. 4.0) as low as 0.01% (up to O.D. 4.0) Input Power 100 - 240V, 50/60 Hz 100 - 240V, 50/60 Hz 100 - 240 V, 50/60 Hz 24.3” W x 12.7” H x 17.5” D 24.3” W x 12.7” H x 17.5” D 24.3” W x 12.7” H x 17.5” D Operating Dimensions 617 mm W x 323 mm H x 445 mm D 617 mm W x 323 mm H x 445 mm D 617 mm W x 323 mm H x 445 mm D Operating Weight 42 lbs. (19.05 kg) 42 lbs. (19.05 kg) 42 lbs. (19.05 kg) Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com RRA13-15 4/13