MICROBIOLOGY AMP-6000® AUTOMATED MICROBIOLOGICAL PLATFORM Microbiological Counting System rapid results simple documentation earlier product release reduced workload simple testing rapid process intervention MICROBIOLOGY AMP-6000® AUTOMATED MPN PLATFORM More than 80% of routine examinations in microbiological laboratories involve enumeration of hygiene indicators. These include e.g. determination of the total mesophilic aerobic germ count and the quantification of Enterobacteriaceae as well as E. coli. The conventional or standard methods used to date are laborious to perform, time-intensive in terms of testing and documentation, and require sufficient expertise in result interpretation. The innovative AMP-6000® system permits these tasks to be automated and thus enables sample throughput in the laboratory to be significantly increased. This automated, miniaturized platform combines the well-known MPN technique for determining the number of microbes ( MPN = Most Probable Number) on microtiter plates. The precision of this statistical method is comparable with that of direct plate counting, thanks to the automated preparation of a series of serial dilutions and the simultaneous examination of up to 32 replicates per dilution. AMP-6000® APS – HIGH-PRECISION WORKSTATION WITH FULL VARIABILITY With the AMP-6000® APS pipetting robot, AmpMedia special nutrient media are placed in sterile 96-well microtiter plates and samples are automatically applied and diluted. Up to 8 samples can be processed per test for 1 parameter, or up to 4 samples for the combined test for 2 parameters for each. The throughput times are coordinated so that additional samples can be prepared in parallel for the next pass. All protocols for the various applications are stored in the software and are easily assignable. Following sample application, the microtiter plates are sealed with a sterile lid and incubated in standard incubators for 24 to 48 hours. Samples and microtiter plates are linked with each other via a barcode system that prevents mixups. SPECIFICATION AMP-6000® APS • Highly flexible and compact liquid handling • If needed, highly effective decontamination by optionally benchtop system available UV lamp • Closed, sturdy Plexiglas housing with front sliding door • Footprint 650 x 610 mm (L x D) • Processing of up to 8 samples in parallel possible • Weight ~ 40 kg • 8 channel pipette volume up to 1000 μl • Fast and quiet operation thanks to the use of modern servomotors • Reproducibility and high-precision pipetting and dispensing results AMP-6000® uv-imager The uv-Imager is used for fluorescence detection when applying fluorescent substrates. It can be used in addition to color and turbidity detection in the LabImager TR, as well as exclusively just for fluorescence detection. This offers the capability to employ various fluorescence substrates for the selective detection of microorganisms. This makes the UV Imager an optional detection system for special applications and consequently broadens the application spectrum. As a result, the simultaneous examination of up to 2 microbiological parameters in just one sample run can be performed. • Highly sensitive, camera-based UV detection system • Transilluminator with 4 UV tubes for excitation (power: 6W) • Excitation wavelength 312nm • Contrast-optimized filter plate • Service display • Compatible with LabImage evaluation software HOW YOU BENEFIT • RELIABLE • FAST - Proven MPN technology with up to 32 replicates - Shortened product release times per dilution - Shorter reaction times - Robust and reliable robotics system - Barcode system - LIMS integration • SIMPLE - Predefined analysis protocols • SAFE - Ready-to-use reagents - Complete data traceability - Optimized workflow - Highly accurate and comparable results - Automated data entry - Internationally validated detection system - Germ count without calibrationn - Short introductory training AMP-6000® LabImager TR AND LabImage SPECIFICATION LabImager TR AND EVALUATION SOFTWARE LabImage EVALUATION SOFTWARE Together with LabImage evaluation software, the AMP • Scanner system for the detection of color changes LabImager TR evaluation unit forms the core of the AMP-6000® platform. • Option for combination with turbidity detection Using a modern scanner system, the LabImager TR detects • Simultaneous analysis of up to 4 samples the bidirectional change of any color. Both pH-indicator • Artificial Intelligence based projection tool for faster systems as well as all chromogenic substrates can thus be results by shortening incubation time used for the selective detection of individual microbial groups. In addition, the system can also be combined with • Calibration tool for self-calibration turbidity detection, which can further increase detection • Barcode system efficiency. • LIMS integration The range of capabilities for detecting color changes, in • Automated diagnosis and result qualification with combination with the unique evaluation software, permits traffic light system the system to benefit from additional application development, as well new applications in the area of microbiological • Ability to visually inspect results diagnostics. • Automated photo-documentation of original results non conform acceptable conform MICROBES DETECTABLE • Total Mesophilic Aerobic Counts • Enterobacteriaceae • Cheese spoiling Clostridia (Patent pending) • Bacillus cereus • Escherichia coli • Staphylococcus aureus (coming soon) • Enterococci (coming soon) • Yeast and Moulds (coming soon) AMP-6000® WORKFLOW 1 SAMPLE PREPARATION 2 AUTOMATIC MEDIA DISPENSING AND SAMPLE DILUTION WITH THE AMP-6000® APS PIPETTING ROBOT 3 INCUBATION IN STANDARD INCUBATORS 4 AUTOMATIC EVALUATION AND DIAGNOSIS USING THE AMP LabImager TR OR AMP uv-imager AND LabImage EVALUATION SOFTWARE ready to AMP up microbial safety VALIDATION AND STANDARDIZATION AmpMedia In cooperation with national and international standardization A wide range of AmpMedia products are available for the bodies, we are working on the standardization of alternative detection and quantification of various microorganisms. microbiological test systems. Our methods are validated All AmpMedia products are available ready to use in liquid according to the specifications of IS0 16140. In addition, we form. Various indicator systems are used, depending on the provide support for specific in-house validation require-application. The formulas have been optimized to meet the ments and also will cooperate with lab service providers of requirements of the AMP-6000® technology, and their your choice for product specific validations. composition is appropriately protected. AmpMedia is exclusively available from SY-LAB or the listed international distributors. Currently available AmpMedia products are listed in the media catalog or on the website. MICROBIOLOGY SUPPORT HELPDESK, EQUIPMENT INSPECTION, TRAINING Future-proof research and development guarantee our We offer a comprehensive service package in order to meet customers permanent advances in micro- and molecular the regular inspection requirements for measuring biology detection methods. Our application lab supports instruments. The package includes periodic testing and, if customers in their daily routine as well as in the creation of necessary, recalibration of devices by means of calibrated new applications and in the execution of method validations. measuring instruments according to ISO and IFS standards, By testing your specific samples, you can personally verify including the preparation of the required documentation. the suitability of the method for your application in advance Verification of the databases and the performance of and with no obligation. required software updates are also included. A training package tailored to your company’s needs enables efficient Our service package includes on-site service, as well as the initial training of staff or refresher training during personnel possibility of remote training and remote maintenance. changes. Distributor: WE DEVELOP SOLUTIONS FOR A SAFER FUTURE SY-LAB Geräte GmbH Tullnerbachstraße 61-65 3011 Neupurkersdorf, Austria www.sylab.com . sales@sylab.com Version 1.0 en