ERWEKA systems Dissolution Offline System Semi-automated dissolution system Semi-automated dissolution testing Dissolution Offline System DT 820 Series As the main control device, the dissolution tester of the DT 820 series is cen-The ERWEKA Dissolution Offline System is the ideal semi-automatic tral to the ERWEKA Dissolution Offline System. By default the Offline System solution for dissolution testing with automated sampling and sub-is equipped with a DT 820 in low-head mode. Optionally, the system can also be operated in high-head mode. sequent sample storage for later analysis. The system is controlled by a DT 820 series dissolution tester with advanced intelligence. The DT 820 series equipped with i-Version comes with integrated IPC 8 Pump intelligence for controlling the offline sampling system, which con-sists of an auto sampling station ASS-8 connected to the DT, a pump The peristaltic pump IPC 8 is the basic pump in the ERWEKA dissolution (peristaltic or piston) and the sample collector of the FRL series for systems and transports the test medium via eight channels to the compact storing the samples in glass tubes or sealed HPLC vials. sample collector of the FRL 854 series. Alternatively, ERWEKA offers the practically maintenance-free PVP 820 within the Dissolution Offline System. This configuration does not require an additional PC or any software and therefore saves space, money and last but not least software validation work. FRL 854 Series The sample collector FRL 6/7/854 offers a space-saving footprint and can store up to 26 samples per vessel. Highlights 100% USP/EP/JP USP methods compliant 1, 2, 5 and 6 Direct control of the complete Sample collector system by DT 820 FRL 6/7/854 NEW 2 3 Overview Dissolution Offline System Comprehensively configurable Dissolution Tester ERWEKA Dissolution Offline Systems DT 820 Series Our semi-automated Dissolution Offline Systems distinguish themselves in partic-ERWEKAs DT 820 series offers advanced intelli-Technical Data ular through a high degree of flexibility. Specify your Offline System tailored to your gence and features for stand-alone operation or individual needs. for control of a complete dissolution offline sam-USP methods 1, 2, 5 and 6 with 6, 7 or Appliance details 8 test stations (826, 827, 828) pling system. It allows storage of up to 60 product in 2 rows test methods. Device control LED display with function keys The DT 820 series can be equipped with 6, 7 or Rotation speed 20 - 220 rpm 8 test stations and be used in high-head or low-Product memory 60 test methods head mode. It offers a traffic light to display the OQ/PQ status, a low evaporation cover as well as Vessel 1000 ml, 2000 ml (optional) an external temperature sensor for checking the Power: 1500 Watt Heating water bath temperature (System Suitability Test). Temperature: 30-50 ° C Water bath 20 l The water bath is designed for easy access and Parallel printer interface, cleaning and made of non-leaking PET. Centering Interface USB printer interface possible rings ensure correct position of vessels and the via adapter USP/EP compliant reinstallation of the vessels at Weight 47 kg any time. The following system configurations are our space-saving solutions and per-Dimensions: 830 mm (including heater) fectly suited for testing of smaller tablet batches: width / depth / height / 640 mm / 940 mm Voltage ± 10 % 115 - 250 VAC; 50 / 60 Hz ■ Dissolution Offline System with DT 820 series, PVP 820 series and FRL 854 series (see picture) Highlights ■ Dissolution Offline System with DT 820 series, IPC 8 and FRL 854 series ■ 100 % USP/JP/EP compliant ■ Automated sample collection ■ Integrated intelligence (i-Version) for controlling the whole system without a computer ■ Temperature measurement in each vessel (optional) ■ Automated tablet drop magazine (optional) ■ Password-protected access control ■ High-head and low-head mode ■ Easy cleaning of the complete system The following system configurations are perfectly suited for testing of larger quantities: ■ Dissolution Offline System with DT 1610 series, PVP 1420 series and FRL 854/2 series (see picture) ■ Dissolution Offline System with DT 1610 series, IPC 16 and FRL 854/2 series 4 5 Dissolution Offline System ERWEKA Dissolution Offline Systems | DT 820 Series ERWEKAs compact sample collector Overview FRL 6/7/854 Pumps for Dissolution Systems The FRL 6/7/854 combines a space-saving foot-Technical Data print with all the familiar functions of the large FRL generation. The legs have been moved inwards, so Channels 6, 7 or 8 that the shortened FRL can be placed crossways Max. capacity 26 sample intervals on the laboratory table. It can be tested with 6, 7 (not for 25 ml test tubes) or 8 channels and, depending on the application, Valve Integrated 3 way valves equipped with different racks for different test tubes or HPLC vials. 26 x 8 / 1.5 ml HPLC vials 26 x 8 / 4.0 ml HPLC vials Peristaltic pumps ERWEKA piston pumps FRL racks 26 x 8 / 10 ml test tubes 18 x 8 / 25 ml test tubes Highlights Weight 25 kg Pumps IPC 8 / 16 PVP 620 / 720 / 820 PVP 1220 / 1420 ■ Dimensions: 6.5 cm shorter and 5 cm lower than predecessor 700 mm / 515 mm / 585 mm Channels 8 or 16 6, 7 or 8 12 or 14 series, which saves 25 cm when rotated by 90° width / depth / hight ■ Works with IPC and PVP pumps Voltage ± 10 % 115 - 250 VAC; 50 / 60 Hz Accuracy +/− 0.5 ml +/− 0.5 ml +/− 0.5 ml ■ Easy cleaning and access to sample tubes ■ Up to 26 rows for extended release formulation testing Media replacement Standard Standard Standard ■ Special procedure for foaming media handling ■ Only when first filtration with Automated flush routine between sampling inter-Double filtration poroplast filters. No media Media replacement possible Media replacement possible vals (optional) replacement possible when when double filtration when double filtration ■ Different racks available double filtration. (interchangeable with FRL x24 series racks) Required type of sample collector FRL 654 / 754 / 854 FRL 654 / 754 / 854 FRL 654 / 754 / 854 System compatibility DT Offline / DT Online DT Offline / DT Online DT Offline / DT Online DT On-/Offline DT On-/Offline DT On-/Offline Filtration down to 0.22 μm for flat Filtration down to 0.22 μm for flat FRL x24 Series Basic pump membrane filters, low maintenance membrane filters, low maintenance Advantages possible with DT 14x/16x, even at high throughput. even at high throughput. needs regular replacement of tubing Best choice for Best choice for dissolution systems dissolution systems 6 7 Dissolution Offline System FRL 6/7/854 | Pumps for Dissolution Systems Contact Are you curious and want to find out more? Head over to our website and download our product brochures, watch videos of our equipment in action or find the ERWEKA dealer of your country. E-Mail: sales@erweka.com Phone: +49 6103 92426-200 Fax: +49 6103 92426-999 support@erweka.com www.erweka.com spareparts@erweka.com www.facebook.com/erweka.gmbh ERWEKA GmbH Pittlerstr. 45 E-Mail: sales@erweka.com Technical specifications of products described are 63225 Langen Phone: +49 6103 92426-200 stated without warranty and subject to change at Germany Fax: +49 6103 92426-999 any time without further notice. v.1.2.4.19