For high throughput, high accuracy applications Refractometer Selection Guide Meeting the needs of your industry and application • Food and Beverage • Sugar Milling, Refining, Processing • Chemical • Pharmaceutical and Toxicology Testing • Petroleum • Flavor, Fragrance, Cosmetics Rudolph Research Analytical, serving its customers TECHNICAL BULLETIN 929 with Integrity, Quality, and Innovation for over fifty years. Choosing A Refractometer 2 A Refractometer that’s right for your industry and application “Just wanted to let you know how pleased our company is with Every industry has its unique application requirements, environmental the J57HA Automatic Refractometers. We currently have two of constraints and operator handling issues with which to contend. It the instruments in service in our sugar testing laboratories and is for this reason, that Rudolph has more than 10 different model are in the process of ordering three additional refractometers. variations to ensure that we have the right solution for your situation. Before the decision was made to switch our laboratories Maybe you are a pharmaceutical company looking for an instrument which can measure below the standard food refractometer range to the J57HA Refractometers, rigorous testing was done on of 1.33 - 1.53 to comply with the USP monograph for Sevoflurane the instrument over the past year in our Quality/Research (refractive index range of 1.2745 - 1.2760) or other halogenated Laboratory. ethers and pharmaceuticals measuring below 1.3 RI. Maybe you’re a flavor, fragrance or essential oil manufacturer or blender dealing It has been our policy when doing research type work, using our with Cinnamic Aldehyde or the many products in this industry having old refractometers, that we place a sample on the prism, set a Refractive Indices greater than 1.60 RI. timer for two minutes, then press the “Read” button until we get Possibly your main concern is not the range of the refractometer but the three readings in a row that are identical (this could take up to reproducibility of results – just listen to what one of our customers has 12 readings). With the J57HA instrument, we place the sample to say after switching to Rudolph after years with another brand: on the prism, press the “Measure” button and in about 15 seconds we have a stable number. The instrument is so stable in fact, that I can honestly say after using the instrument for over a year, we have never had a different reading from the original J357-MMC-CP measurement, no matter how many times we repeatedly press the “Measure” button.” – R.R., Senior Process Chemist, Western Sugar Cooperative J57HA How to use this guide Although there are many common problems that are similar across all industry and then call us to help solidify your model selection. Our industries: like sample cleaning, sample cross contamination, dirty prism, technical sales representatives understand that the initial price is an improper water zero, some problems are unique or have a different important part of the purchasing decision but only part of that decision; level of importance to a particular industry. This model selection guide equally, if not more important is purchasing an instrument that works allows you to see which models are the most popular in your industry and as intended for the application and meets all relevant standards, why. Just select the category that best reflects your regulations and requirements in the area in which you work. Food and Beverage .............................................4 Petroleum ...........................................................8 Sugar Milling, Refining, Processing .....................5 Flavor, Fragrance, Cosmetics ...............................9 Chemical .............................................................6 Model Comparison Charts ........................ 10 & 11 Pharmaceutical and Toxicology Testing ...............7 Calibration and Documentation ........................12 Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com The Rudolph Advantage 3 Below are a few of the reasons customers replaced their old refractometer with a J-Series from Rudolph Problem Solution You are tired of arguments over shadowline interpretation J-Series Internal Reflection Refractometers use scratch proof on your Abbe Refractometer. One person says the material is on artificial sapphire prisms that measure the reflected light not the specification, one person says it’s not. In addition, scratches on the transmitted light, like the Abbe, so dark samples measure as easily as glass prism make visual interpretation even more difficult. clear samples. Just put a drop of sample on the prism, press measure and walk away. No shadow line, no manual balancing or interpretation. Waterbath maintenance is costly and time consuming. Theoretically it should be easy – just top it off with water every week, The J-Series has an electronic peltier temperature control clean it out and add new algaecide once a month. So why does the solution that is right for you. Select your temperature through the bath always seem to be low on water and covered with green slime? touch screen and watch the instrument quickly come to temperature and make a measurement all in one easy step. Our customers say it best: “This instrument has greatly reduced our sample time and improved our accuracy. Calibration of the instrument is easy and Your old refractometer was great when you bought it but now it rarely required. We have had no problems or issues with the two is being repaired more and more often while measurement instruments that we currently have in service... instability wastes time and money. I would highly recommend the Rudolph J57HA Refractometer over any other brand of refractometer that I have used or tested throughout my many years working in the sugar industry.” Why switch to a Rudolph Research Refractometer? Superior temperature control and easy to clean prism For semi-solid and highly evaporative For samples close to ambient For most samples 10° from ambient select samples more than 10° from ambient select select a model without a presser J Series standard temperature controlled a model with a contact presser (CP option) sample cover (CC option) Contact Presser option (CP) Temperature controlled sample cover (CC) Contact Concave Shallow Sample Sample sample Sample sample sample well presser cover with no Shallow presser Shallow Prism Prism sample well Temperature controlled prism sample well Rudolph’s dual temperature control system Measuring RI or Brix far from ambient air temperature Rudolph Research Analytical is the only refractometer manufacturer to The J157/257/357 shallow well with temperature control from the offer electronic temperature control from both prism and presser sample presser and prism surface offers superior temperature control surfaces. The requirements of an electronically temperature controlled while still maintaining ease of cleaning. Rudolph’s temperature refractometer operating close to ambient air temperature are very different controlled presser creates a mini temperature controlled environment from the temperature control requirements of a refractometer operating where the entire sample is held at the measurement temperature. This more than 10°C from ambient air temperature. Only the Rudolph J Series design minimizes the inaccuracies created by temperature gradients is designed to be the perfect refractometer for both applications. across the sample as deep well prisms fight to control temperature from the prism surface while the air and upper part of the sample have widely Measuring RI or Brix close to ambient air temperature divergent temperatures. (See Figure lower left) The J57’s shallow sample well and presserless design makes cleaning easier than deep well prism designs while still maintaining Other manufacturer’s compromise accuracy. The deep sample well of competing refractometers is not From the pictures below one can see that other manufacturers have needed when there is less than a 10°C difference between the prism to make a compromise with the depth and angle of sample well. temperature and air temperature because the temperature gradient Since these manufacturers use one sample well and cover design for both across the sample is small. temperature applications, they end up with a sample well that is too narrow and deep. The deep sample well makes cleaning needlessly Other manufacturers at all temperatures hard at ambient temperature while failing to provide ideal temperature Presser lid with no temperature control function control when the sample and air temperature are more than 10°C from the 30°C air temperature desired measurement temperature. Sample Rudolph Manufacturer 1 Manufacturer 2 DEEP SAMPLE WELL Temperature gradient DESIGN CREATES DIFFICULT TO CLEAN AREAS Prism 20°C prism temperature Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Food and Beverage 4 • Seed oils • Juices • Teas • Soy bean oils • Juice concentrates • Sodas • Candy • Fruit products • Sauces • Syrups • Confections • Soups • Dairy products • Starch • Jams • Edible oils • Milk • Jellies • Coffee extracts • Hydrolysis products • Soft drinks • HFCS • Vegetable products Feature Highlight Flat, easy to clean prism – No matter how good the refractometer is, the results will only be right if the instrument is clean. Rudolph’s flat prism design makes cleaning easy, even with sticky syrups. The flat low profile sample well with a sample volume of less than 1ml is easily cleaned by wiping with a common paper towel. The J57 single cleaning surface with scratch-proof sapphire prism makes this a popular choice for high throughput food laboratories. Models Specifications Features and Benefits J47 J57 Brix results can only achieve accuracy in the real world if • Measurement Range: the sample area is cleaned properly. Rudolph’s shallow 1.33 - 1.53 RI; 0 - 95% Brix prism design has no corners or steep angles to trap • Accuracy: ±0.00002 RI, ±0.02 Brix sticky samples thus avoiding or reducing the problem of • Electronic Temperature Control: cross contamination between samples. The simple, easy Fixed temperature selection: 20°C to use user interface with large measure button and key lock and 25°C out feature makes it a popular choice for busy factory labs. Gloved hands and elbows like the big measure key. J157 • Measurement Range: The J157-CC-AM with non-contact cover (CC) and Auto 1.33 - 1.53 RI; 0 - 95% Brix Measure (AM) are popular option choices for food applications where the sample must be protected from • Accuracy: ±0.00002 RI, ±0.02 Brix a harsh environment and custom scales are required. • Electronic Temperature Control: Auto Measure (AM) allows for easy measurement on/off Flexible temperature selection between by just lifting the presser cover to stop a measurement and 15°C - 50°C closing the cover to start a measurement. J357-CC-AM • Measurement Range: J357-CC-AM is best for high temperature food 1.26 - 1.70 RI; 0 - 95% Brix applications where the product is more stable when measured at a high temperature. For example, the J357 • Accuracy: 0.00004 RI, 0.03 Brix temperature control system is set for 70°C and temperature • Electronic Temperature Control: correction is set for 20°C. The J357 heavy duty temperature Flexible temperature selection between control system ensures the sample stays at 70°C while the 15°C - 100°C; TB option: allows 15°C - instrument displays a temperature corrected result of what 110°C with one hour boost to 120°C the sample would read if it were 20°C. Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Sugar Milling, Refining, Processing 5 • Cane sugar milling and refining • Beet sugar milling and refining • Invert sugar • Liquid sugar • Confectionary sugar • Molasses • Brown sugar Feature Highlight Small funnel design Over-flow J157-KVP Pour through refractometers are designed for area to avoid Model measuring cane or beet juice in a sugar mill. This spillage design has two important benefits: cleaning becomes part of the sample loading process and This port is connected to measurement time is reduced because one sample tubing and flows to waste is poured in after another making the design attractive for seasonal operators. The small funnel design forces improved sample flushing by increasing Exit tubing the number of sample pours. to waste Models Specifications Features and Benefits J57 The J57HA’s simple interface and easy to clean prism • Measurement Range: surface make it one of our most popular models for 1.33 - 1.53 RI; 0 - 95% Brix the sugar industry. Temperature control to 20°C and 25°C makes it perfect for molasses and high Brix • Accuracy: ±0.00002 RI, ±0.02 Brix samples. Measurement speed can be improved by • Electronic Temperature Control: using Temperature Correction in conjunction with Fixed temperature selection: 20°C Temperature Control, allowing measurements to be and 25°C made accurately almost as soon as the sample is placed on the prism. J157 The J157-CC-AM is also quite popular with sugar • Measurement Range: factory labs. The non contact cover (CC) with built in 1.33 - 1.53 RI; 0 - 95% Brix electronic heating and cooling improves performance in harsh conditions. The Auto Measure (AM) feature • Accuracy: ±0.00002 RI, ±0.02 Brix allows the closing and opening of the cover to start • Electronic Temperature Control: and stop the measurement eliminating the need for Flexible temperature selection between the operator to touch the interface. Very popular for 15°C - 50°C factory floors where air temperature varies dramatically: cold at night and hot during the day. J157-PTW The J157-PTW can be operated as a pour through • Measurement Range: refractometer when measuring juices and then by 1.33 - 1.53 RI; 0 - 95% Brix loosening one thumb screw and lifting the hinged presser J157-KVP the instrument can be used like a J57. This allows the J157- • Accuracy: ±0.00002 RI, ±0.02 Brix PTW to measure molasses and other high Brix samples. • Electronic Temperature Control: The J157-KVP has a vertical prism that allows KVP: Select any temperature between suspended solids to fall past the prism surface instead 15°C - 30°C of on to the prism. The small funnel volume design Thumb screw PTW: Select any temperature between with integrated over flow funnel increases sample 15°C - 40°C flushes and reduces spillage. The J157-KVP is often Feature highlight favored in applications with highly turbid samples. above Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Chemical 6 Water Based: Petroleum Based: • Resins • Glues • Oil based paints • Polymers • • • Polymers • Glycols • Fine chemicals • Resins • Coolants • Ethylene • Fluranes • Solvents • Gels • Acids • PET: polyethylene terephthalate • Plastics J257-CP-H Feature Highlight H Option suggested applications • Hydrofluoric acid at all concentrations All J Series refractometers are designed for high • HCl and similar acids at all concentrations chemical resistance from the outset with the wetted • Strong alkalis Hastelloy parts being sapphire, Tectron® and 316 stainless • Strong oxidizing agents Contact steel. However, when using HCl and other caustic Presser (CP) compounds, 316 stainless steel is not resistant enough. For plastic manufacturers who measure liquids and For these applications Rudolph offers an extended solids like PET, Rudolph has a Contact Presser (CP) Hastelloy chemical resistance option where the sample dish with extra weight. and cover are made from Hastelloy (H Option). (CP) Option suggested application • PET: polyethylene terephthalate Water-Based Chemical Models Specifications Features and Benefits J57HA A refractometer can Hastelloy • Measurement Range: only achieve real world 1.33 - 1.53 RI; 0 - 95% Brix accuracy if the prism is cleaned properly between • Accuracy: ±0.00002 RI, ±0.02 Brix samples. The flat open • Electronic Temperature Control: sample area has no corners Fixed temperature selection: to trap even sticky materials and is resistant to almost all 20°C and 25°C solvents including Acetone, Toluene and similar organics. Choose (HA) option for HFl and HCl acids. J157 DUAL TEMPERATURE CONTROL SYSTEM • Measurement Range: Unlike other temperature controlled refractometers, the 1.33 - 1.53 RI; 0 - 95% Brix J157/257/357 have temperature control from both above • Accuracy: ±0.00002 RI, ±0.02 Brix and below the sample. The Sample Cover is controlled to the same temperature as the prism and, when lowered, • Electronic Temperature Control: is designed to provide a temperature controlled micro Flexible temperature selection between environment that provides unrivaled temperature 15°C - 50°C stability, fast measurement time and minimal evaporation. Depending on options, the Sample Cover can also be used to initiate measurement. (Select AM option) Petroleum-Based Chemical Models Specifications Temperature Controlled Concave Sample Cover (CC) J257 Sample No sample contact, one surface cleaning • Measurement Range: Shallow 1.26 - 1.70 RI; 0 - 95% Brix sample well Temperature controlled prism • Accuracy: 0.0001 RI; 0.1 Brix OPTIONAL CONTACT PRESSER (CP OPTION) • Electronic Temperature Control: Flexible temperature selection between The J157/257/357 are available with an optional Temperature 15°C - 70°C Controlled Sample Presser (CP option) that touches the sample. Compared with the standard temperature controlled cover, the optional CP Presser reduces the empty volume of the measurement area thereby decreasing evaporation and at J357-CP-AM • Measurement Range: the same time helping to evenly spread semi solid materials 1.26 - 1.70 RI; 0 - 95% Brix over the measurement prism. This feature offers improved performance on many samples such as PET and Glycerine. • Accuracy: 0.00004 RI; 0.03 Brix Temperature Controlled Contact Presser (CP) • Electronic Temperature Control: Flexible temperature selection between Sample Shallow 15°C - 100°C; TB option: allows 15°C - sample well 110°C with one hour boost to 120°C Prism Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Pharmaceutical and Toxicology Testing 7 • Total Parenteral Nutrition (TPN) • USP <831> • Toxicology testing (Urine SG) • EP 2.2.6 • Pharmacy compounding • Enflurane and drug diversion • Sevoflurane Feature Highlight F Official Monographs, USP 31 / Sevoflurane 3867 Enflurane, Sevoflurane and similar halogenated ethers are •Sevoflurane O used extensively for the induction and maintenance of F F general anesthesia. Their manufacture must comply with F F F F C4H3F7O 200.05 specifications from the USP/EP or relevant pharmacopeias. Propane, 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)- Many of these pharmacopeias require the measurement of Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether refractive index. For example, the US Pharmacopeia requires [ 28523-86-6]. that sevoflurane has a refractive index of 1.2745 - 1.2760 at Refractive index (831): between 1.2745 and 1.2760, at 20°C 20°C. For 21CFR Part 11 compliance choose MMC option. Pharmaceutical Models Specifications Features and Benefits J357 • Measurement Range: 1.26 - 1.70 RI; USP General Subchapter <831> Refractive Index States: 0 - 95% Brix ...Although the standard temperature for Pharmacopeial • Accuracy: 0.0001 RI; 0.1 Brix measurements is 25°C, many of the refractive index specifications in the individual monographs call for • Electronic Temperature Control: determining this value at 20°C. The temperature should Flexible temperature selection between be carefully adjusted and maintained, since the refractive 15°C - 70°C index varies with the temperature... ...To achieve the theoretical accuracy of ±0.0001, it is necessary to calibrate the instrument against a standard provided by the manufacturer and to check frequently the J457 • Measurement Range: 1.26 - 1.70 RI; temperature control and cleanliness of the instrument by 0 - 95% Brix determining the refractive index of distilled water, which is 1.3330 at 20°C and 1.3325 at 25°C... • Accuracy: 0.00004 RI; 0.03 Brix The J357-MMC-CC provides the refractive index • Electronic Temperature Control: range, accuracy, performance and 21CFR Part 11 Flexible temperature selection between compliance demanded by big pharma making this our 15°C - 100°C most popular pharmaceutical model. Medical Testing and Toxicology Models Specifications Features and Benefits J57HA • Measurement Range: 1.33 - 1.53 RI; The J-Series Refractometer is chosen by more toxicology 0 - 95% Brix, 1.000 - 1.0500 Urine SG labs than any other brand. These customers know that 0.0002 • Accuracy: 0.0002 Urine SG; Urine SG accuracy must be validated regularly and Rudolph’s ±0.00002 RI, ±0.02 Brix J57 ensures that the refractive index performance and calibration requirements meet government regulations. The • Electronic Temperature Control: J57HA’s standard sample volume is 500 micro liters but this can Fixed temperature selection: 20°C and 25°C be reduced to 100 micro liters by selecting the J57HA-SV. J57HA-UF-SP • Measurement Range: 1.33 - 1.53 RI; 0 - 95% Brix, 1.000 - 1.0500 Urine SG SAMSHA labs doing hundreds of toxicology samples per • Accuracy: 0.0002 Urine SG; day prefer to eliminate the human factor and choose ±0.00002 RI, ±0.02 Brix large scale automation. The J57HA-UF-SP is combined with a custom automation solution that minimizes sample • Electronic Temperature Control: use and replaces the tested sample to the testing vial. Fixed temperature selection: 20°C and 25°C J57TPN • Measurement Range: 1.33 - 1.53 RI; For large hospitals doing their own pharmaceutical 0 - 95% Brix, 1.000 - 1.0500 Urine SG compounding, ensuring that their Total Parenteral • Accuracy: 0.0002 Urine SG; Nutrition formulas are accurate is life critical. ±0.00002 RI, ±0.02 Brix The J57TPN was specifically customized to meet • Electronic Temperature Control: USP<797>. Please contact the factory for the white Fixed temperature selection: 20°C and 25°C paper on this application. Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Petroleum 8 • ASTM D1218 • ASTM D1747 • ASTM D5006 • Oils • Fuels • Lubricants • Waxes Feature Highlight The Temperature Boost (TB) option provides two benefits: The Rudolph Research Analytical J357 is able to control 1. The maximum temperature of the refractometer is increased temperature to 100°C because it has a unique dual from 100°C to 110°C. temperature control system where heat is applied to both 2. The maximum temperature of the temperature control sides of the sample. system is increased to 120°C for a period of 60 minutes. At However, there are still applications where temperatures the end of 60 minutes the temperature control will shut off above 100°C are needed. To accommodate the need to and the instrument will cool down to ambient temperature measure above 100ºC, the Temperature Boost (TB) option for a period of 1 hour. was developed for the J357 Refractometer Series. Other manufacturers at all temperatures Rudolph J357 Presser lid with no temperature control function or liquid contact Temperature controlled sample coverConcave Sample Sample sample DEEP SAMPLE WELL cover DESIGN CREATES Temperature gradient Shallow DIFFICULT TO Temperature controlled prism sample well CLEAN AREAS Prism Models Specifications Features and Benefits J57WR-UF-SP • Measurement Range: 1.26 - 1.7 RI; 0 - 95% Brix The J57WR-UF-SP is often combined with Rudolph’s • Accuracy: 0.0001 RI; 0.1 Brix density meter for automated measure of petroleum • Electronic Temperature Control: fuels, oil and waxes. Combining a refractometer with an Fixed temperature selection: ECS autosampler eliminates the need for manual loading. 20°C and 25°C J357-NDS-CC Designation: D 1747-99 Standard Test Method for Refractive Index of Viscous Materials 1. Scope • Measurement Range: 1.1 This test method covers the measurement of 1.26 - 1.70 RI; 0 - 95% Brix refractive indexes, accurate to two units in the fourth • Accuracy: decimal place, 0.00004 RI; 0.03 Brix of transparent and light-colored viscous hydrocarbon liquids and melted solids which have • Electronic Temperature Control: refractive indexes in the range between 1.33 and 1.60, and Flexible temperature selection between at temperatures from 80 to 100°C. Temperatures lower 15°C - 100°C; TB option: allows 15°C - than 80°C can be used provided that the melting point of 110°C with one hour boost to 120°C the sample is at least 10°C below the test temperature. The J357-NDS is able to control temperature to 100°C because it has a unique dual temperature control system where heat is applied to both sides of a sample, meeting the needs of all the ASTM standards. For added flexibility for cloud points occurring closer to 120°C select the TB option. Please contact the factory for help with this option. Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Flavor, Fragrance, Cosmetics 9 • Perfumes • Cremes • Skin cleansers • Waxes • Lotions • Natural oils • Lemon, lime, orange • Sandalwood • Palm Feature Highlight YOUR CUSTOM BOTTLES Automation Flexibility AND RACK HERE • Rudolph’s AutoSampler can be loaded with up to 240 samples • Combine Refractive Index measurements with a polarimeter, density meter, and colorimeter for simultaneous measurements of: – Density/Specific Gravity – Color – Optical Rotation/Specific Rotation – Refractive Index • Up to three different rinse solvents available for use; fully programmable • Emergency samples measured at any time without stopping the AutoSampler or moving sample vials • Data can be saved in Excel or PDF formats for integration into the laboratory LIMS or SAP system Models Specifications Features and Benefits J57WR • Measurement Range: 1.26 - 1.70 RI; 0 - 95% Brix Many aromatic substances such as Cinnamic/Aldehyde • Accuracy: 0.0001 RI; 0.1 Brix have refractive indices above 1.60 RI. For this reason, • Electronic Temperature Control: most flavor/fragrance labs choose a wide RI range Fixed temperature selection: refractometer like the J57WR. 20°C and 25°C J457 OMB • Measurement Range: 1.26 - 1.70 RI; 0 - 95% Brix Excellent model for the flavor and fragrance industries. Designed to be used with automation. Not • Accuracy: 0.0001 RI; 0.1 Brix suitable for waxes or VERY high viscosity samples. Seen • Electronic Temperature Control: above in combination with optical rotation, density/SG Fixed temperature selection: and color. 20°C and 25°C J357 This is our most popular stand alone model for the • Measurement Range: flavor/fragrance industry. Its wide RI range 1.2 - 1.7 1.26 - 1.70 RI; 0 - 95% Brix measures all known products. Its non-contact sample cover • Accuracy: 0.0001 RI; 0.1 Brix improves performance for evaporative samples. Presser • Electronic Temperature Control: can be upgraded to allow automation in the future. Flexible temperature selection between Sample Non-contact concave 15°C - 70°C Temperature sample cover controlled prism Shallow sample well J457 • Measurement Range: 1.26 - 1.70 RI; 0 - 95% Brix More accuracy and features generally needed by the • Accuracy: 0.00004 RI; 0.03 Brix industry. This model is sometimes chosen when the • Electronic Temperature Control: customer sells most of their product to the pharmaceutical Flexible temperature selection between industry and wants 21CFR Part 11 compliance. 15°C - 100°C Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Model Comparison Chart: Standard Food Refractive Index Range Applications 10 Models Specifications J57HA J57-HA-UF-SP J57TPN J157-CC J157PTW J157KVP Measurement Range 1.33 - 1.53 RI, 0 - 95% Brix, 1.0000 - 1.0400 Urine SG Measurement Scales Refractive Index (RI) Brix (% sucrose), Temperature Corrected Brix, Refractive Index (RI) Brix (% sucrose), Temperature Corrected Brix, Temperature Corrected RI, Urine SG Temperature Corrected RI, Urine SG and 100 User Programmable Scales Resolution 0.00001 RI, 0.01 Brix, 0.0001 Urine SG Reproducibility ±0.00002 RI, ±0.015 Brix, ±0.0001 Urine SG Accuracy ±0.00002 RI, ±0.02 Brix, 0.0001 Urine SG Control Temperature 20ºC and 25ºC 15°C to 50°C 15°C to 40°C 15°C to 30°C Ambient Temperature Limit 10ºC to 40ºC Sample Temperature Limit -20ºC to +250ºC Temperature Correction Range 18 to 95ºC (for pure sucrose) Wavelength 589.3nm (other wavelengths available) Light Source Light Emitting Diode (exp life>1,000,000 measurements) Calibration 1, 2 or 10 point using water or NIST traceable standards Communication Interface 2 RS232 ports, 1 parallel port, 1 auxiliary port and USB adaptor available Models J57HA J57-HA-UF-SP J57TPN J157-CC J157PTW J157KVP Options Concave Cover No Sample Contact CC Option Standard Contact Sample Not Available Presser CP Option Available Automeasure Feature AM Option Available Not Available Hastelloy Feature H Option Available H Option Available Not Available Small Volume Sample Well (100 µ liters) SV Option Available SV Option Available Micro Flow Cell With Sealed Prism Not Available UF-SP Option Available Not Available Pour In Options Not Available PTW Option Standard KVP Option Standard Data Storage Not Available MMC Option Available Not Available Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Model Comparison Chart: Wide Refractive Index Range Applications 11 Models Specifications J57WR J57WR-UF-SP J257-CC J357-NDS Measurement Range 1.26 - 1.70 RI, 0 - 95% Brix Measurement Scales Refractive Index (RI) Brix (% sucrose) Refractive Index (RI) Brix (% sucrose) 100 User Programmable Scales Resolution 0.0001 RI, 0.01 Brix 0.0001 RI, 0.01 Brix 0.00001 RI, 0.01 Brix Reproducibility ±0.0001 RI, ±0.1 Brix ±0.0001 RI, ±0.1 Brix ±0.00002 RI, ±0.015 Brix Accuracy 0.0001 RI, 0.1 Brix 0.0001 RI, 0.1 Brix 0.00004 RI, 0.03 Brix Control Temperature 20ºC and 25ºC 15ºC to 70ºC 15ºC to 100ºC Ambient Temperature Limit 10ºC to 40ºC Sample Temperature Limit -20ºC to +250ºC Temperature Correction Range 18 to 95ºC (for pure sucrose) Wavelength 589.3nm (other wavelengths available) Light Source Light Emitting Diode (exp life>1,000,000 measurements Calibration 1,2 or 10 point using water or NIST traceable standards Communication Interface 2 RS232 ports, 1 parallel port, 1 auxiliary port and USB adaptor available Models J57WR J57WR-UF-SP J257-CC J357-NDS Options Concave Cover No Sample Contact CC Option Standard Automeasure Feature Not Available AM Option Available Contact Sample Presser CP Option Available Hastelloy Feature Acid Resistance H Option Available H Option Available Not Available Small Volume Sample Well (100 µ liters) SV Option Available SV Option Available Temperature Boost TB Option Available Not Available 21 CFR Part 11 Compliance/Data MMC Option Available Storage Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com Calibration and Documentation 12 Office Style (parallel) Printer These come in two main styles: 1. Inkjet Printer 2. Laser Printer These office style printers have the following advantages: • Large paper size (American standard 8 1/2 x 11 inches or A4) required by cGLP/cGMP and often preferred by regulating bodies such as FDA • Multiple readings per page • Inexpensive replacement cost • Easy access to consumables Rudolph Research Analytical This sample was measured on a J357 refractometer, serial number 12129, manufactured by Rudolph Research Analytical, Hackettstown, NJ. Last Calibration : Aug 20, 2006 12:23:42 Lot Identifier : Test print Calibration Kits Operator Name : _______________________ Rudolph Research Analytical offers three different calibration fluid kits. Each fluid kit comes complete with Operator Signature : _______________________ NIST Traceable Certificates for each fluid. No Sample ID Measurement Temp. Time Date All Purpose ------------------------------------------------------------------------- 1 2712 1.57023 Refractive Index 20.0C 12:51:44 Aug 22, 2006 2 2712 1.57023 Refractive Index 20.0C 12:51:59 Aug 22, 2006 A23180 General Use NIST Traceable Calibration Fluids Kit 3 2712 1.57023 Refractive Index 20.0C 12:52:06 Aug 22, 2006 Kit consists of the following (5) NIST traceable calibration fluids ------------------------------------------------------------------------- n =3 Average =1.57023 Standard Deviation =0.000000 (1 oz. each): • A21752-1.3330-W RI Certified Water 20°C with table for 10-70°C • A21752-1.350-20/Brix 10 • A21752-1.460-20/Brix 70 • A21752-1.516-Multi Temperature Fluid (20º, 30º, 40º) Strip Impact Printer • A21752-1.650-20 nominal RI Rudolph Research Analytical Receipt printers have Measurement the following advantages: 1.60006 Refractive Index Pharmaceutical • Small footprint Temperature A23180-VLR NIST Traceable Calibration Fluids Kit 20.0C • Designed for rough industrial environments (Special version for measuring halogenated ethers and Temperature Correction • Does not use thermal paper general pharmaceuticals) off • Industrial product with long model life, Kit consists of the following (5) NIST traceable calibration fluids Time 12:25:28 so that the printer is often available for (1 oz each): many years • A21752-1.29-20 Date • A21752-1.3330-W RI Certified Water 20°C with table for 10 - 70°C Aug 22, 2006 • A21752-1.460-20/Brix 70 Last Calibration • A21752-1516-Multi Temperature Fluid (20°C, 30°C, 40°C) Aug 20, 2006 12:23:42 • A21752-1.650-20 nominal RI ----------------------- Operator Name Toxicology Testing ----------------------- A23180-USG NIST Traceable Calibration Fluids Kit Operator Signature (Special version for validating 4th decimal place Urine specific This sample was measured on a J357 gravity refractometers) refractometer, serial number 12129, manufactured by Rudolph Research Kit consists of the following (5) NIST traceable calibration fluids Analytical, Hackettstown, NJ. (1 oz each) at the major decisions points: • A21752-1.3330-W 1.0000 - Urine SG • A21752-1.0010 Urine SG Barcode Reader • A21752-1.0030 Urine SG All Rudolph refractometers can be equipped with a barcode reader. • A21752-1.0200 Urine SG The barcode reader has flexible programming enabling it to work with • Calibration fluid above 1.0300 (nominal for calibration) various barcode standards: Code 39, Codabar, Interleaved 2 of 5 , UPC-A and others. All Calibration Fluid RI values are subject to change based on availability. Many individual Refractive Index Calibration Fluids are available at various indices and temperatures. Contact a Customer Service Representative for assistance in choosing a fluid that is right for your application. Rudolph Research Analytical 55 Newburgh Road, Hackettstown, NJ 07840 USA • Phone: 973-584-1558 • Fax: 973-584-5440 • E-mail: info@rudolphresearch.com • Internet: www.rudolphresearch.com 4/11 5m